- Prostaglandin D2 contributes to cisplatin-induced neuropathic pain in rats via DP2 receptor in the spinal cord
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Li Y, Kim WM, Kim SH, You HE, Kang DH, Lee HG, Choi JI, Yoon MH
- KMID: 2510309
- Korean J Pain.
- 2021 Jan;34(1):27-34.
- doi: 10.3344/kjp.2021.34.1.27
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a major reason for stopping or changing anticancer therapy. Among the proposed pathomechanisms underlying CIPN, proinflammatory processes have attracted increasing attention. Here we assessed... -
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- Imperatorin Suppresses Degranulation and Eicosanoid Generation in Activated Bone Marrow-Derived Mast Cells
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Jeong KT, Lee E, Park NY, Kim SG, Park HH, Lee J, Lee YJ, Lee E
- KMID: 2380290
- Biomol Ther.
- 2015 Sep;23(5):421-427.
- doi: 10.4062/biomolther.2015.023
Imperatorin has been known to exert many biological functions including anti-inflammatory activity. In this study, we investigated the inhibitory effects of imperatorin on the production of inflammatory mediators in mouse... -
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- Curcumin Inhibits the Activation of Immunoglobulin E-Mediated Mast Cells and Passive Systemic Anaphylaxis in Mice by Reducing Serum Eicosanoid and Histamine Levels
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Li X, Lu Y, Jin Y, Son JK, Lee SH, Chang HW
- KMID: 2048327
- Biomol Ther.
- 2014 Jan;22(1):27-34.
Curcumin is naturally occurring polyphenolic compound found in turmeric and has many pharmacological activities. The present study was undertaken to evaluate anti-allergic inflammatory activity of curcumin, and to investigate its... -
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- The Influence of IgE on Cultured Human Mast Cells
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Frandsen P, Krohn IJ, Hoffmann H, Schiotz PO
- KMID: 2260286
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):409-414.
- doi: 10.4168/aair.2013.5.6.409
PURPOSE: The mast cell plays a pivotal role in the human immune response. Crosslinking of 2 IgE molecules bound to the high affinity IgE receptor (FcepsilonRI) on the surface of... -
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- Role of Prostaglandin D2 in the Pathogenesis of Asthma
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- KMID: 2299463
- Korean J Asthma Allergy Clin Immunol.
- 2012 Sep;32(3):144-149.
Prostaglandin D2 is a major lipid mediator released from activated mast cells of which metabolite 9alpha,11beta-prostaglandin F2 are used as a biomarker of mast cell activation in various type of... -
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- Possible Role of Heme Oxygenase-1 and Prostaglandins in the Pathogenesis of Cerebral Malaria: Heme Oxygenase-1 Induction by Prostaglandin D2 and Metabolite by a Human Astrocyte Cell Line
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Kuesap J, Na-Bangchang K
- KMID: 1102782
- Korean J Parasitol.
- 2010 Mar;48(1):15-21.
- doi: 10.3347/kjp.2010.48.1.15
Astrocytes are the most abundant cells in the central nervous system that play roles in maintaining the blood-brain-barrier and in neural injury, including cerebral malaria, a severe complication of Plasmodium... -
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