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Phytochemical Characterization of Vitex negundo Leaves: a Potent Antiandrogenic and Antioxidant Agent

Sharath J, Shahin Taj RA, Bhagya M

This study was conducted to characterise phytochemicals and to explore the biological activities of Vitex negundo leaves. The washed, course powder of V. negundo leaves were extracted with different solvents...
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Effect of Puffing in the Extraction of Active Ingredients from the Roots of Paeonia lactiflora and Astragalus membranaceus

Lee H, Jang KW

In Asia, the roots of Paeonia lactiflora and Astragalus membranaceus have been used as therapeutic agents for thousands of years. Once the medicinal plants are harvested, they are dried and...
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miRNA-200b Signature in the Prevention of Skin Cancer Stem Cells by Polyphenol-enriched Blueberry Preparation

Alsadi N, Mallet JF, Matar C

Exposure of the skin to solar UV radiation leads to inflammation, DNA damage, and dysregulation of cellular signaling pathways, which may cause skin cancer. Photochemoprevention with natural products is an...
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Effects of Blue Light on Eye of Zebra Fish and Protective Role of Polyphenolic Compounds

Nam S, Kim YK, Kim K, Hong HS, Yu SY, Kim ES

Purpose: To investigate the oxidative damage and changes of retinas by blue light through zebrafish and to confirm the protective effect of polyphenol on retina cells using grape seed-derived polyphenols. Methods:...
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Effects of plant-derived natural products on inflammatory bone destructive disease

Ko SY

Rheumatoid arthritis, osteoarthritis, and periodontal disease are bone destructive diseases mainly caused by inflammation. Various studies are being conducted to develop treatments for inflammatory bone destructive diseases. Many of these...
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Comparison of Biological Activities of Korean Halophytes

Lee JM, Yim MJ, Lee DS, Lee MS, Park YG, Jeon JH, Choi G

Halophytes are expected to possess abundant secondary metabolites and various biological activities because of habitat in extreme environments. In this study, we collected 14 halophytes (Asparagus oligoclonos, Calystegia soldanella, Carex...
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Histomorphometric evaluation of bone healing capacity of epigallocatechin-3-gallate-loaded β-TCP bone substitute in rabbit calvarial defects

Park JW

This study investigated the effect of epigallocatechin-3-gallate (EGCG)-loaded microporous β-tricalcium phosphate (β-TCP) bone substitute in the bone healing of rabbit calvarial defects. New bone formation induced by β-TCP incorporating two...
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Antioxidant and Anti-inflammatory Activity of Six Halophytes in Korea

Lee JM, Yim MJ, Choi G, Lee MS, Park YG, Lee DS

The aim of this study was to measure and compare polyphenol content, antioxidant, and anti-inflammatory activity of six halophytes (Limonium tetragonum, Suaeda glauca, Suaeda japonica, Salicornia europaea, Triglochin maritimum, and...
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Rice Cakes Containing Dietary Fiber Supplemented with or without Artemisia Annua and Gynura Procumbens Merr. Alleviated the Risk Factors of Metabolic Syndrome

Yoon NR, Yoon S, Lee SM

We investigated whether the consumption of Korean rice cakes enriched with dietary fiber with or without polyphenol rich plants might decrease the risk factors of metabolic syndrome (MetS). Rice cakes...
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Effects of quercetin derivatives from mulberry leaves: Improved gene expression related hepatic lipid and glucose metabolism in short-term high-fat fed mice

Sun X, Yamasaki M, Katsube T, Shiwaku K

BACKGROUND/OBJECTIVES: Mulberry leaves contain quercetin derivatives, which have the effects of reducing obesity and improving lipid and glucose metabolism in mice with obesity. It is not clear whether or not...
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The Effect of Polyphenols Isolated from Cynanchi wilfordii Radix with Anti-inflammatory, Antioxidant, and Anti-bacterial Activity

Jeong S, Lee S, Choi WJ, Sohn UD, Kim W

Recently, Cynanchi wilfordii Radix has gained wide use in Asian countries as a functional food effective for relieving fatigue, osteoporosis, and constipation, particularly in menopausal disorders. However, its anti-inflammatory and...
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Antioxidant activities and nutritional characteristics of smoked duck marinated in natural curing agent

Bark YO

PURPOSE: This study investigated the question of whether the addition of natural ingredients (pear fermented solution, celery powder, vitamin C) in curing agents may influence antioxidant activities and nutritional characteristics...
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Protective effects of green tea polyphenol against cisplatin-induced nephrotoxicity in rats

Ahn TG, Kim HK, Park SW, Kim SA, Lee BR, Han SJ

OBJECTIVE: This study is to compare the effects of green tea polyphenol (GTP) pre-treatment with those of GTP post-treatment on cisplatin (CP)-induced nephrotoxicity in rat. METHODS: Male Sprague-Dawley rats were randomly...
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Quality Characteristics of Yanggaeng Supplemented with Sanghwang Mushroom (Phellinus linteus) Mycelia

Hong SS, Jung EK, Kim AJ

  • KMID: 2332409
  • J Korean Diet Assoc.
  • 2013 Aug;19(3):253-264.
The principal objective of this study was to examine the quality characteristics of yanggaeng supplemented with powder derived from Sanghwang mushroom (Phellinus linteus) mycelia. We analyzed the potential of utilizing...
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Antiproliferation and Redifferentiation in Thyroid Cancer Cell Lines by Polyphenol Phytochemicals

Kang HJ, Youn YK, Hong MK, Kim LS

Thyroid carcinogenesis is accompanied by loss of thyroid-specific functions and refractory to radioiodine and thyroid stimulating hormone (TSH) suppression therapy. Redifferentiating agents have been shown to inhibit tumor growth and...
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Preventive Effects of Oligomerized Polyphenol on Estradiol-Induced Prostatitis in Rats

Kim DS, Lee EJ, Cho KS, Yoon SJ, Lee YH, Hong SJ

PURPOSE: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS, NIH category III) accounts for 90-95% of prostatitis cases. However, standard treatment has not yet been established. It is known that polyphenols have...
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The Antiproteinuric Effects of Green Tea Polyphenol on Cyclosporine A-Induced Acute Renal Injury in Mice

Shin BC, Kim HL, Chung JH

  • KMID: 1867694
  • Korean J Nephrol.
  • 2006 Nov;25(6):913-921.
BACKGROUND:It has been reported that there is association between cyclosporine (CsA) nephrotoxicity and proteinuria. The aim of this study was to investigate the anti-proteinuric effects of green tea polyphenol (GTP)...
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The Effect of Green Tea Polyphenol on Plasma Glucose, Lipid Levels and Antioxidant Systems in Type 2 Diabetic Patients

Suk JH, Kim MK, Ju JW, Han JS, Park JH

BACKGROUND: Green-tea polyphenol (GTP) is a well known antioxidant with favorable effect on blood glucose and lipid level in animal models. We were to investigate the effects of GTP on...
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The Effect of Green Tea Extract on Cisplatin in Cervical Cancer Cell Lines

Ahn TG, Kim DW, Lee BR, Han SJ

  • KMID: 2013153
  • Korean J Obstet Gynecol.
  • 2006 Mar;49(3):592-598.
OBJECTIVE: Green tea polyphenol (GTP) has been shown to have anti-tumor properties in a wide variety of experimental systems. In this study, we evaluated the effects of GTP on the...
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Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties

Yoon JH, Baek SJ

There is persuasive epidemiological and experimental evidence that dietary polyphenols have anti-inflammatory activity. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have long been used to combat inflammation. Recently, cyclooxygenase (COX)...
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