- Effect of pre-operative medication with paracetamol and ketorolac on the success of inferior alveolar nerve block in patients with symptomatic irreversible pulpitis: a double-blind randomized clinical trial
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Kumar U, Rajput A, Rani N, Parmar P, Kaur A, Aggarwal V
- KMID: 2520785
- J Dent Anesth Pain Med.
- 2021 Oct;21(5):441-449.
- doi: 10.17245/jdapm.2021.21.5.441
Background: The efficacy of local anesthesia decreases in patients with symptomatic irreversible pulpitis. Therefore, it was proposed that the use of premedication with an anti-inflammatory drug might increase the success... -
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- Comparison of Vitex agnus-castus Extracts with Placebo in Reducing Menopausal Symptoms: A Randomized Double-Blind Study
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Naseri R, Farnia V, Yazdchi K, Alikhani M, Basanj B, Salemi S
- KMID: 2469480
- Korean J Fam Med.
- 2019 Nov;40(6):362-367.
- doi: 10.4082/kjfm.18.0067
BACKGROUND: Menopausal symptoms have remarkable negative effects on women's quality of life, justifying the need to assess various therapeutic options. This research aimed to determine the effectiveness of Vitex agnus-castus... -
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- Inhaled Corticosteroids and Placebo Treatment Effects in Adult Patients With Cough: A Systematic Review and Meta-analysis
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Lee SE, Lee JH, Kim HJ, Lee BJ, Cho SH, Price D, Morice AH, Song WJ
- KMID: 2459189
- Allergy Asthma Immunol Res.
- 2019 Nov;11(6):856-870.
- doi: 10.4168/aair.2019.11.6.856
PURPOSE: Inhaled corticosteroids (ICSs) are often considered an empirical therapy in the management of patients with cough. However, ICS responsiveness is difficult to interpret in daily clinical practice, as the... -
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- A Randomized, Multicenter, Phase III Trial to Evaluate the Efficacy and Safety of Polmacoxib Compared with Celecoxib and Placebo for Patients with Osteoarthritis
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Lee M, Yoo J, Kim JG, Kyung HS, Bin SI, Kang SB, Choi CH, Moon YW, Kim YM, Han SB, In Y, Choi CH, Kim J, Lee BK, Cho S
- KMID: 2412245
- Clin Orthop Surg.
- 2017 Dec;9(4):439-457.
- doi: 10.4055/cios.2017.9.4.439
BACKGROUND: The aim of this study was to evaluate the safety and analgesic efficacy of polmacoxib 2 mg versus placebo in a superiority comparison or versus celecoxib 200 mg in... -
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- Efficacy and Safety of Bitopertin in Patients with Schizophrenia and Predominant Negative Symptoms: Subgroup Analysis of Japanese Patients from the Global Randomized Phase 2 Trial
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Hirayasu Y, Sato SI, Shuto N, Nakano M, Higuchi T
- KMID: 2365014
- Psychiatry Investig.
- 2017 Jan;14(1):63-73.
- doi: 10.4306/pi.2017.14.1.63
OBJECTIVE: The aim of the present study was to perform a subgroup analysis of data from a phase II global, multi-center, randomized, double-blind, placebo-controlled study to evaluate the efficacy and... -
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- Effects of cetirizine in dogs with chronic atopic dermatitis: a randomized, double blind, placebo-controlled trial
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Hsiao YH, Chen C, Willemse T
- KMID: 2412611
- J Vet Sci.
- 2016 Dec;17(4):549-554.
- doi: 10.4142/jvs.2016.17.4.549
This study was conducted to evaluate the effects of cetirizine in dogs with atopic dermatitis (AD) while fulfilling Favrot's diagnostic clinical criteria. Dogs received either 3 mg/kg cetirizine (n =... -
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- Prevalence and Clinical Impact of IgE-Mediated Food Allergy in School Children With Asthma: A Double-Blind Placebo-Controlled Food Challenge Study
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Krogulska , Dynowski J, Funkowicz , Malachowska B, Wasowska-Krolikowska K
- KMID: 2130261
- Allergy Asthma Immunol Res.
- 2015 Nov;7(6):547-556.
- doi: 10.4168/aair.2015.7.6.547
PURPOSE: Recent studies indirectly suggest a possible link between food allergy (FA) and asthma. Most of them have evaluated the occurrence of FA in asthmatic children, especially in the first... -
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- Efficacy of Probiotic Therapy on Atopic Dermatitis in Children: A Randomized, Double-blind, Placebo-controlled Trial
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Yang HJ, Min TK, Lee HW, Pyun BY
- KMID: 2260682
- Allergy Asthma Immunol Res.
- 2014 May;6(3):208-215.
- doi: 10.4168/aair.2014.6.3.208
PURPOSE: To evaluate a therapeutic efficacy of probiotics mixture (probiotics) in the treatment of children with mild-to-moderate atopic dermatitis (AD). METHODS: Randomized, double-blind, placebo-controlled, parallel trial with a washout period of... -
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- Placebo Effect in Clinical Trial Design for Irritable Bowel Syndrome
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Shah E, Pimentel M
- KMID: 2381168
- J Neurogastroenterol Motil.
- 2014 Apr;20(2):163-170.
Ongoing efforts to improve clinical trial design in irritable bowel syndrome have been hindered by high placebo response rates and ineffective outcome measures. We assessed established strategies to minimize placebo... -
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- Psychiatric Applications of Placebos
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Sohn I, Kim I
- KMID: 2287778
- Korean J Psychopharmacol.
- 2014 Apr;25(2):37-42.
As the placebo effect is inevitable in almost all types of treatment implemented in the context of the doctor-patient relationship, it would be a wise strategy to try to enhance... -
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- A Clinical Trial and Extension Study of Infliximab in Korean Patients with Active Rheumatoid Arthritis despite Methotrexate Treatment
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Kim J, Ryu H, Yoo DH, Park SH, Song GG, Park W, Cho CS, Song YW
- KMID: 1779410
- J Korean Med Sci.
- 2013 Dec;28(12):1716-1722.
- doi: 10.3346/jkms.2013.28.12.1716
Currently, infliximab is given for disease control for active rheumatoid arthritis (RA) patients despite methotrexate treatment. However, the efficacy and safety of infliximab in Korean patients has not been assessed... -
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- Evidence-Based Korean Pharmacological Treatment Guideline for Depression, Revised Edition (II) : Antidepressant Efficacy Compared with Placebo, Difference in Efficacy of Antidepressants, and Appropriate Time of Efficacy Judgment in Antidepressant Therapy
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Sung SH, Park SC, Han KM, Won ES, Lee HY, Koo JW, Paik JW, Lee KM, Jeon HJ, Lee MS, Shim SH, Ko YH, Lee KJ, Han C, Ham BJ, Choi J, Hwang TY, Oh KS, Park YC, Lee MS, Hahn SW
- KMID: 2343633
- J Korean Neuropsychiatr Assoc.
- 2013 Sep;52(5):372-385.
OBJECTIVES: The purpose of this study was to suggest recommendations of antidepressant efficacy compared with placebo, difference in efficacy of antidepressants, and appropriate time of efficacy judgment in antidepressant therapy. METHODS:... -
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- Placebo Effects and Clinical Trials of Neuropsychiatric Drugs
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Kim SW, Jang JE, Yoon JS
- KMID: 2250345
- Korean J Biol Psychiatry.
- 2012 Nov;19(4):164-171.
The placebo effect, a response observed during the placebo arm of a clinical trial, is produced by the psychobiological action of the placebo as well as by other potential contributors... -
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- The Effect of Red-Yeast-Rice Supplement on Serum Lipid Profile and Glucose Control in Subjects with Impaired Fasting Glucose or Impaired Glucose Tolerance
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Kang MR, Kim JY, Hyun YJ, Kim HJ, Yeo HY, Song YD, Lee JH
- KMID: 2261193
- Korean J Nutr.
- 2008 Jan;41(1):31-40.
This study was aimed at evaluating the effect of red-yeast-rice supplementation on cholesterol-lowering and glucose control in subjects with impaired fasting glucose (IFT) or impaired glucose tolerance (IGT). We conducted... -
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- Imaging of Dopamine Release Induced by Pharmacologic and Nonpharmacologic Stimulations
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Cho SS, Kim SE
- KMID: 2313036
- Nucl Med Mol Imaging.
- 2007 Apr;41(2):158-165.
Technological advances in molecular imaging made it possible to image synaptic neurotransmitter concentration in living human brain. The dopaminergic system has been most intensively studied because of its importance in... -
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- Diagnosis and Treatment of Food Allergy in Children
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Kim WK
- KMID: 2314419
- Pediatr Allergy Respir Dis.
- 2006 Dec;16(4):274-283.
Food allergy is a common allergic manifestation in early childhood. However, some medical practitioners remain sceptical about the role of food allergies in a number of clinical syndromes, such as... -
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- Effectiveness of aromatherapy in smoking cessation
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Kwon GI, Ha SW, Cheong YS, Park EW, Yoo SM
- KMID: 2295066
- J Korean Acad Fam Med.
- 2001 Jul;22(7):1105-1111.
BACKGROUND: The harmfulness of cigarette smoking is widely known, as a result the interest of smoking cessation is increasing. Some smoking cessation methods have tried at clinical setting, but with... -
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- Antioxidant Vitamin Supplementation and Levels of Circulating Cellular Adhesion Molecules
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Song KE, Chae SC, Jun JE, Park WH, Chun BY, Joung HJ, Choi YS, Cho SH
- KMID: 2226006
- Korean J Clin Pathol.
- 2001 Jun;21(3):176-182.
BACKGROUND: The oxidative modification of lipids and the endothelial expression of adhesion molecules are key events in the pathogenesis of atherosclerosis. The appropriate antioxidants that protected and slowed the progression... -
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- Double-Blind Placebo-Controlled Randomized Clinical Trial of Zolmitriptan in Acute Treatment of Migraine
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Lee SB, Kim YI, Choi YB, Chung SW, Yang DW, Lee KS, Kwon SU, Kim JS, Kim BS
- KMID: 1812913
- J Korean Neurol Assoc.
- 2001 Jan;19(1):29-35.
BACKGROUND: Zolmitriptan (Zomig) is a selective serotonin agonist at the 5-hydroxytryptamine (5-HT1B/1D) receptor that acts both centrally and peripherally in the trigeminal nucleus and axon terminals and at adjacent meningeal... -
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- Double-Blind Placebo-Controlled Randomized Clinical Trial of Topiramate Add-On Therapy in Medically Intractable Partial Epilepsies
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Lee BI
- KMID: 2016302
- J Korean Neurol Assoc.
- 1998 Dec;16(6):809-819.
BACKGROUND: To evaluate the efficacy and safety of topiramate (TPM) as add-on therapy in medically intractable partial epilepsies. METHODS: This study was a multicenter double-blind placebo-controlled randomized parallel group... -
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