- Regulation of the Gene Expression of Airway MUC5AC Mucin through NF-κκB Signaling Pathway by Artesunate, an Antimalarial Agent
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Kim Ki, Hossain R, Ryu J, Lee HJ, Lee CJ
- KMID: 2545711
- Biomol Ther.
- 2023 Sep;31(5):544-549.
- doi: 10.4062/biomolther.2023.048
In this study, artesunate, an antimalarial agent, was investigated for its potential effect on the gene expression of airway MUC5AC mucin. The human pulmonary epithelial NCI-H292 cells were pretreated with... -
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- Meclofenamate Suppresses MUC5AC Mucin Gene Expression by Regulating the NF-kB Signaling Pathway in Human Pulmonary Mucoepidermoid NCI-H292 Cells
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Ryu J, Kim Ki, Hossain R, Lee M, Hong JT, Lee HJ, Lee CJ
- KMID: 2541789
- Biomol Ther.
- 2023 May;31(3):306-311.
- doi: 10.4062/biomolther.2023.035
The current study aimed to reveal the potential effect of meclofenamate, a nonsteroidal anti-inflammatory drug, on the gene expression of airway MUC5AC mucin. Human pulmonary mucoepidermoid NCI-H292 cells were pretreated... -
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- Pathologic View of Intraductal Papillary Mucinous Neoplasm
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Kang YN
- KMID: 2541909
- Korean J Pancreas Biliary Tract.
- 2023 Apr;28(2):27-31.
- doi: 10.15279/kpba.2023.28.2.27
Among pancreatic cystic lesions, mucinous cystic neoplasm (MCN) and intraductal papillary mucinous neoplasm (IPMN) of the pancreas are precursor lesions of pancreatic adenocarcinoma. IPMN is characterized by intraductal papillary proliferation... -
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- A Case of Endocrine Mucin-Producing Sweat Gland Carcinoma of the Eyelid
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Kang JE, Kim SE, Yang SW
- KMID: 2539919
- J Korean Ophthalmol Soc.
- 2023 Feb;64(2):149-153.
- doi: 10.3341/jkos.2023.64.2.149
Purpose: We report an endocrine mucin-producing sweat gland carcinoma diagnosed by biopsy in a patient who presented with an eyelid mass. Case summary: A 64-year-old male presented with a 3 ×... -
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- Betulin, an Anti-Inflammatory Triterpenoid Compound, Regulates MUC5AC Mucin Gene Expression through NF-kB Signaling in Human Airway Epithelial Cells
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Hossain R, Kim Ki, Jin F, Lee HJ, Lee CJ
- KMID: 2534703
- Biomol Ther.
- 2022 Nov;30(6):540-545.
- doi: 10.4062/biomolther.2022.093
Betulin is a triterpenoid natural product contained in several medicinal plants including Betulae Cortex. These medicinal plants have been used for controlling diverse inflammatory diseases in folk medicine and betulin... -
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- Involvement of IKK/IkBα/NF-kB p65 Signaling into the Regulative Effect of Engeletin on MUC5AC Mucin Gene Expression in Human Airway Epithelial Cells
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Hossain R, Kim Ki, Li X, Lee HJ, Lee CJ
- KMID: 2532880
- Biomol Ther.
- 2022 Sep;30(5):473-478.
- doi: 10.4062/biomolther.2022.088
In this study, we examined whether engeletin exerts an effect on the gene expression of MUC5AC mucin, in human pulmonary epithelial NCI-H292 cells. The cells were pretreated with engeletin for... -
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- Death from Malignant Transformation of Untreated Mucinous Borderline Tumor: Case Report
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Jang W, Kang TM, Kim Y, Wang AR, Yoon HR, Ko KS, Choi J
- KMID: 2533078
- Korean J Leg Med.
- 2022 Aug;46(3):90-93.
- doi: 10.7580/kjlm.2022.46.3.90
Mucinous borderline tumors (MBT) of the ovary with mild to moderately atypical epithelial cells that produce mucin rarely recur and very rarely become malignant after surgery. Due to their low... -
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- Pedunculated mucinous cystic neoplasm of the liver: a case report
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Ha SW, Hwang S, Han H, Han SI, Hong SM
- KMID: 2532079
- J Yeungnam Med Sci.
- 2022 Jul;39(3):250-255.
- doi: 10.12701/yujm.2021.01256
In 2010, the World Health Organization classified mucin-producing bile duct tumors of the liver into two distinct entities; mucinous cystic neoplasm of the liver (MCN-L) and intraductal papillary mucinous neoplasm... -
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- Interaction between Dietary Factors and Gut Microbiota in Ulcerative Colitis
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Sung MK
- KMID: 2530346
- J Dig Cancer Res.
- 2022 Jun;10(1):31-38.
- doi: 10.52927/jdcr.2022.10.1.31
Ulcerative colitis (UC) exhibits chronic intestinal inflammatory conditions with cycles of relapse and remission. The incidence is rapidly growing in Asian countries including South Korea possibly due to changes in... -
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- Evaluation of host and bacterial gene modulation during Lawsonia intracellularis infection in immunocompetent C57BL/6 mouse model
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Kirthika P, Park S, Jawalagatti V, Lee JH
- KMID: 2530435
- J Vet Sci.
- 2022 May;23(3):e41.
- doi: 10.4142/jvs.21274
Background: Proliferative enteritis caused by Lawsonia intracellularis undermines the economic stability of the swine industry worldwide. The development of cost-effective animal models to study the pathophysiology of the disease will... -
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- Prognosis in primary mucinous ovarian carcinoma: focusing on the five pathological findings indicating metastatic mucinous carcinoma to the ovary
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Lee Sw, Sung JA, Jung M, Kim H, Lee C
- KMID: 2536840
- J Gynecol Oncol.
- 2022 Mar;33(2):e18.
- doi: 10.3802/jgo.2022.33.e18
Objective Pathological features indicating metastatic mucinous carcinoma to the ovary (MMCO) have been rarely reported in primary mucinous ovarian carcinoma (PMOC). However, little is known about how often they are observed... -
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- The Effect of Formula-based Nutritional Treatment on Colitis in a Murine Model
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Jang S, Kim Y, Lee C, Kwon B, Noh J, Jee JJ, Yoon SS, Koh H, Park S
- KMID: 2523562
- J Korean Med Sci.
- 2021 Dec;36(50):e342.
- doi: 10.3346/jkms.2021.36.e342
Background: Exclusive enteral nutrition (EEN) induces remission in pediatric Crohn's disease (CD). The exact mechanism of EEN therapy in CD is unknown, but alteration of the intestinal microflora after EEN... -
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- Peroxiredoxin 2 Inhibits Lipopolysaccharide Induced Mucin Expression and Reactive Oxygen Species Production in Human Airway Epithelial Cells
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Kim JH, Jo S, Lee S, Yoo GM, Na HG, Choi YS, Bae CH, Song SY, Kim YD
- KMID: 2523398
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2021 Dec;64(12):887-895.
- doi: 10.3342/kjorl-hns.2021.00171
Background and Objectives Peroxiredoxin (Prx) is an antioxidant enzyme involved in signaling pathway. Prx2 is the most abundant in mammalian gray matter neurons and has protective role under oxidative stress.... -
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- Eriodictyol Inhibits the Production and Gene Expression of MUC5AC Mucin via the IκBα-NF-κB p65 Signaling Pathway in Airway Epithelial Cells
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Yun C, Lee HJ, Lee CJ
- KMID: 2522251
- Biomol Ther.
- 2021 Nov;29(6):637-642.
- doi: 10.4062/biomolther.2021.091
In this study, we investigated whether eriodictyol exerts an effect on the production and gene expression of MUC5AC mucin in human pulmonary epithelial NCI-H292 cells. The cells were pretreated with... -
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- Subepithelial Tumor-like Gastric Cancer
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Jung K, Park MI
- KMID: 2516629
- Korean J Helicobacter Up Gastrointest Res.
- 2021 Jun;21(2):106-114.
- doi: 10.7704/kjhugr.2021.0006
Subepithelial tumor-like gastric cancer (SET-like GC) is a special type of gastric cancer with a relatively low prevalence of approximately 1%. Diagnosing SET-like GC is challenging because the tumor is... -
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- A Case of Mucinous Cystadenocarcinoma in Labial Mucosa of Upper Lip
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Um JH, Jo DI, Kim SH
- KMID: 2516454
- Korean J Head Neck Oncol.
- 2021 May;37(1):43-46.
- doi: 10.21593/kjhno/2021.37.1.43
Mucinous cystadenocarcinoma (MCA) is a malignant tumor that mainly occurs in the breast or ovary, but MCA is internationally rarely reported in head and neck region. Especially MCA in minor... -
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- Kaempferol Regulates the Expression of Airway MUC5AC Mucin Gene via IκBα-NF-κB p65 and p38-p44/42-Sp1 Signaling Pathways
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Li X, Jin F, Lee HJ, Lee CJ
- KMID: 2515279
- Biomol Ther.
- 2021 May;29(3):303-310.
- doi: 10.4062/biomolther.2020.149
In the present study, kaempferol, a flavonoidal natural compound found in Polygonati Rhizoma, was investigated for its potential effect on the gene expression and production of airway MUC5AC mucin. A... -
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- Appendiceal Mucinous Neoplasm Detected due to the Protrusion of Mucin, in the Absence of Appendiceal Distension: A Case Report
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Park JW, Park MG, Song JS, Cho HJ, Kim YJ
- KMID: 2509980
- J Dig Cancer Res.
- 2020 Dec;8(2):109-111.
A mucocele is a cystic dilatation of the vermiform appendix that contains mucous material. The symptoms associated with it are not specific and the diagnosis is seldom made prior to... -
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- KLF4 Regulates Goblet Cell Differentiation in BMI1＋ Reserve Intestinal Stem Cell Lineage during Homeostasis
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Katano T, Bialkowska AB, Yang VW
- KMID: 2508916
- Int J Stem Cells.
- 2020 Nov;13(3):424-431.
- doi: 10.15283/ijsc20048
Krüppel-like factor 4 (KLF4) is a zinc-finger transcription factor, expressed in villus cells of the intestinal epithelium, that promotes cellular differentiation and tissue homeostasis. Previous studies suggest that BMI1＋ cells... -
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- Double Primary Mucinous Eccrine Adenocarcinomas Each Occurring Separately on the Left Eyelid and Right Eyelid with a Time Lag
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Lee SY, Kang MJ, Seo JM, Lee YB, Yu DS
- KMID: 2506588
- Korean J Dermatol.
- 2020 Sep;58(8):551-553.
A 57-year-old man presented with a tender, solitary, 0.3 cm-sized, subdermal nodule on the left periocular area for several months. He had surgery three times for recurrent primary mucinous eccrine... -
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