- Clinical Outcomes of Moderately Hypofractionated Concurrent Chemoradiotherapy for Newly Diagnosed Glioblastoma
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Kim N, Lim DH, Choi JW, Lee JI, Kong DS, Seol HJ, Nam DH
- KMID: 2538958
- Yonsei Med J.
- 2023 Feb;64(2):94-103.
- doi: 10.3349/ymj.2022.0352
Purpose: Hypofractionated radiotherapy (HypoRT) has recently been implemented in patients with glioblastoma (GBM) receiving concurrent temozolomide. Lymphopenia during treatment (LDT) is considered an important prognostic factor of clinical outcomes for... -
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- Safety and Temporal Pattern of the Lymphocyte Count During Fingolimod Therapy in Patients With Multiple Sclerosis: Real-World Korean Experience
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Huh SY, Kim SH, Kim KH, Kwon YN, Kim SM, Kim SW, Shin HY, Chung YH, Min JH, So J, Lim YM, Kim KK, Kim NH, Nam TS, Kang SY, Oh J, Oh Si, Sohn E, Kim HJ
- KMID: 2534754
- J Clin Neurol.
- 2022 Nov;18(6):663-670.
- doi: 10.3988/jcn.2022.18.6.663
Background and Purpose Fingolimod (FTY) inhibits lymphocyte egress from lymphoid organs to cause lymphopenia, but the clinical implications of FTY-induced lymphopenia are not fully understood. We aimed to determine the... -
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- Impact of hematologic toxicities during concurrent chemoradiation for cervical cancer
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Shi F, Yoder AK, Mach C, Dalwadi S, Anderson ML, Hall TR, Ludwig MS
- KMID: 2527269
- Obstet Gynecol Sci.
- 2022 Mar;65(2):176-187.
- doi: 10.5468/ogs.21308
Objective To evaluate the prognostic significance of hematological toxicities during cervical cancer treatment. Methods Patients treated for cervical carcinoma with definitive chemoradiation were identified. Toxicities were assessed during weeks 1 to... -
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- Role of Interleukin-7 in the Development of and Recovery from Radiation-Induced Lymphopenia: A Post-hoc Analysis of a Prospective Cohort
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Byun HK, Chung SY, Kim KJ, Seong J
- KMID: 2521572
- Cancer Res Treat.
- 2021 Oct;53(4):962-972.
- doi: 10.4143/crt.2020.1053
Purpose Radiation-induced lymphopenia is associated with worse outcomes in solid tumors. We assessed the impact of interleukin-7 (IL-7), a key cytokine in lymphocyte homeostasis, on radiation-induced lymphopenia. Materials and Methods A... -
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- Lymphopenia following pancreaticoduodenectomy is associated with pancreatic fistula formation
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Cohen JT, Charpentier KP, Miner TJ, Cioffi WG, Beard RE
- KMID: 2516245
- Ann Hepatobiliary Pancreat Surg.
- 2021 May;25(2):242-250.
- doi: 10.14701/ahbps.2021.25.2.242
Backgrounds/Aims: Post-operative pancreatic fistulas (POPF) are a major source of morbidity following pancreaticoduodenectomy (PD). This study aims to investigate if persistent lymphopenia, a known marker of sepsis, can act as... -
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- Characteristics of COVID-19 Patients Who Progress to Pneumonia on Follow-Up Chest Radiograph: 236 Patients from a Single Isolated Cohort in Daegu, South Korea
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Jung HK, Kim JY, Lee MS, Lee JY, Park JS, Hyun M, Kim HA, Kwon YS, Choi SW, Moon SM, Suh YJ
- KMID: 2507250
- Korean J Radiol.
- 2020 Nov;21(11):1265-1272.
- doi: 10.3348/kjr.2020.0564
Objective: We investigated the prevalence of pneumonia in novel coronavirus disease 2019 (COVID-19) patients using chest radiographs to identify the characteristics of those with initially negative chest radiographs, who were... -
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- Effect of Cumulative Dexamethasone Dose during Concomitant Chemoradiation on Lymphopenia in Patients with Newly Diagnosed Glioblastoma
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Lee C, Ahn S, Park JS, Song JH, Hong YK, Jeun SS
- KMID: 2507778
- Brain Tumor Res Treat.
- 2020 Oct;8(2):e12.
- doi: 10.14791/btrt.2020.8.e12
Background Lymphopenia frequently occurs after concomitant chemoradiation (CCRT) in patients with glioblastoma (GBM) and is associated with worse overall survival (OS). A few studies have tried to identify risk factors... -
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- The Prognostic Value of Treatment-Related Lymphopenia in Nasopharyngeal Carcinoma Patients
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Liu LT, Chen QY, Tang LQ, Guo SS, Guo L, Mo HY, Chen MY, Zhao C, Guo X, Qian CN, Zeng MS, Bei JX, Tan J, Chen S, Hong MH, Shao JY, Sun Y, Ma J, Mai HQ
- KMID: 2403471
- Cancer Res Treat.
- 2018 Jan;50(1):19-29.
- doi: 10.4143/crt.2016.595
PURPOSE: This study was conducted to evaluate the prognostic value of treatment-related lymphopenia in patients with nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: A total of 413 consecutive stage II-IVb NPC patients... -
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- Lymphopenia at 4 Days Postoperatively Is the Most Significant Laboratory Marker for Early Detection of Surgical Site Infection Following Posterior Lumbar Instrumentation Surgery
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Iwata E, Shigematsu H, Okuda A, Morimoto Y, Masuda K, Nakajima H, Koizumi M, Tanaka Y
- KMID: 2362181
- Asian Spine J.
- 2016 Dec;10(6):1042-1046.
- doi: 10.4184/asj.2016.10.6.1042
STUDY DESIGN: Case control study. PURPOSE: To identify the most significant laboratory marker for early detection of surgical site infection (SSI) using multiple logistic regression analysis. OVERVIEW OF LITERATURE: SSI is a... -
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- Pretreatment Lymphopenia, Poor Performance Status, and Early Courses of Therapy Are Risk Factors for Severe Bacterial Infection in Patients with Multiple Myeloma during Treatment with Bortezomib-based Regimens
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Hyun SY, Han SH, Kim SJ, Jang JE, Kim Y, Cho H, Lee JY, Cheong JW, Min YH, Song JW, Kim JS
- KMID: 2363688
- J Korean Med Sci.
- 2016 Apr;31(4):510-518.
- doi: 10.3346/jkms.2016.31.4.510
The aim of this study was to identify the risk factors associated with severe bacterial infection (SBI) in multiple myeloma (MM) patients during treatment with bortezomib-based regimens. A total of... -
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- Analysis of in vitro apoptosis induced by virulent Korean isolate of classical swine fever virus in peripheral blood B cell line
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Kim SM, Lim SI, Song JY, Hyun BH
- KMID: 1431986
- Korean J Vet Res.
- 2012 Dec;52(4):259-262.
Classical swine fever (CSF) is a highly contagious disease among swine that has an important economic impact on worldwide. One clinical symptom of CSF is leukopenia, in particular lymphopenia, which... -
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- The Association of Lymphopenia with the Clinical Severity in the Korean Children Admitted to the Hospital with Pandemic (H1N1) 2009 Infection
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Chun JK, Cha BH, Uh Y, Kim HY, Kim YK, Kwon W, Kim HM
- KMID: 2170331
- Infect Chemother.
- 2011 Feb;43(1):36-41.
- doi: 10.3947/ic.2011.43.1.36
BACKGROUND: Critical illness due to pandemic (H1N1) 2009 is an emerging threat to global health. In this study, lymphopenia was focused on as a major risk factor for a critical... -
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- The Analysis of Exercise on the Immune Responses
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Kwak YS, Jin YW, Paik IY, Um SY
- KMID: 2150606
- Immune Netw.
- 2005 Jun;5(2):117-123.
- doi: 10.4110/in.2005.5.2.117
The immune response to any stimulus is complex, requiring coordinated action by several types of cells in a tightly regulated sequence. Thus, a physical stress such as exercise may act... -
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- Lymphopenia after Mediastinal Irradiation in Lung Cancer
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Oh YK, Ha CS, Park HC, Lee SL, Ryu SY, Kee KH, Jeon HJ
- KMID: 1840728
- J Korean Soc Ther Radiol Oncol.
- 2002 Mar;20(1):34-40.
PURPOSE: This study was undertaken to retrospectively evaluate white blood cell kinetics, especially lymphocyte depression after different treatments, and to find the correlation between immunosuppression and large blood volume and... -
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