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Cellular and Molecular Mechanisms of Intestinal Fibrosis

Wu X, Lin X, Tan J, Liu Z, He J, Hu F, Wang, Y, Chen M, Liu F, Mao R

Intestinal fibrosis associated stricture is a common complication of inflammatory bowel disease usually requiring endoscopic or surgical intervention. Effective anti-fibrotic agents aiming to control or reverse intestinal fibrosis are still...
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Evaluation of Serum Zonulin and Occludin Levels in Bipolar Disorder

Zengil S, Laloğlu E

Objective The etiology of bipolar disorder (BD) is still not fully understood. Little is currently known about the relationship between the interaction the gastrointestinal system and brain function and BD....
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Effect of Probiotics/Synbiotics on Postoperative Outcomes in Patients Undergoing Abdominal Surgery

Park IJ

Environmental factors, drugs, diet, and surgery alter the composition of the gut microbiota leading to the production of different metabolites or toxins that can cause disease or delay postoperative recovery....
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Effect of administration of synbiotics mixture containing Bifidobacterium longum and xylooligosaccharide on fecal microbiota and defecation characteristics in healthy volunteers

Lee JS, Park HS, Kyung M, Jo SE, Chang MJ

Purpose: The effect of prebiotics intake after administration of a synbiotics mixture (a probiotic, Bifidobacterium longum, and a prebiotic, xylooligosaccharide containing sugar [XOS]) on human intestinal microflora and defecation characteristics...
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Characteristics of Faecal Microbiota in Korean Patients with Clostridioides difficile-associated Diarrhea

Jeon YD, Ann HW, Lee WJ, Kim JH, Seong H, Kim JH, Ahn JY, Jeong SJ, Ku NS, Yeom JS, Yong D, Lee K, Choi JY

BACKGROUND: The intestinal microbiota plays an important role in the pathogenesis of Clostridioides difficile-associated diarrhea, and regional and racial characteristics influence the microbiome composition and diversity. We investigated the intestinal...
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Autoimmunity and intestinal colonization by Candida albicans in patients with type 1 diabetes at the time of the diagnosis

Gürsoy S, Koçkar T, Ugan Atik , Önal Z, Önal H, Adal E

PURPOSE: Type 1 diabetes mellitus (T1DM) is a chronic and immune-mediated disease, which is characterized by the progressive destruction of pancreatic beta cells. T1DM precipitates in genetically susceptible individuals through...
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Microbiota, a key player in alcoholic liver disease

Cassard AM, Ciocan D

Alcoholic liver disease (ALD) is a major cause of morbidity and mortality worldwide. Only 20% of heavy alcohol consumers develop alcoholic liver cirrhosis. The intestinal microbiota (IM) has been recently...
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Small Intestinal Bacterial Overgrowth and Irritable Bowel Syndrome: A Bridge between Functional Organic Dichotomy

Ghoshal UC, Shukla R, Ghoshal U

The pathogenesis of irritable bowel syndrome (IBS), once thought to be largely psychogenic in origin, is now understood to be multifactorial. One of the reasons for this paradigm shift is...
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Spontaneous and transgenic rodent models of inflammatory bowel disease

Prattis S, Jurjus A

Inflammatory Bowel Disease (IBD) is a multifactorial disorder with many different putative influences mediating disease onset, severity, progression and diminution. Spontaneous natural IBD is classically expressed as Crohn's Disease (CD)...
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Interplay between Intestinal Microbiota and Host Immune System

Mazmanian , Lee YK

Whether we are aware or not, diverse microorganisms are living on almost all environmentally exposed surfaces on our body without eliciting harmful immune responses. In fact, recent understanding from numerous...
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Recent Methodological Approaches to Human Microbiome

Bae JW

Human body is one of the most complex and diverse microbial ecosystem in which various microbes are living together with their hosts. Starting with Louis Pasteur's postulation that human health...
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Intestinal Microbiota and the Development of Allergy in Infants

  • KMID: 2299597
  • Korean J Asthma Allergy Clin Immunol.
  • 2007 Dec;27(4):220-225.
We analyzed fecal microbiota in Japanese infants with or without allergy at 6 months using a culture technique. Determination of allergy was based on clinical symptoms, signs, and skin prick...
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