- Sweroside plays a role in mitigating high glucose-induced damage in human renal tubular epithelial HK-2 cells by regulating the SIRT1/NF-κB signaling pathway
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Ma X, Guo Z, Zhao W, Chen L
- KMID: 2547319
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):533-540.
- doi: 10.4196/kjpp.2023.27.6.533
Sweroside is a natural monoterpene derived from Swertia pseudochinensis Hara. Recently, studies have shown that sweroside exhibits a variety of biological activities, such as anti-inflammatory, antioxidant, and hypoglycemic effects. However, its... -
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- Cornuside inhibits glucose-induced proliferation and inflammatory response of mesangial cells
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Li X, Guo L, Huang F, Xu W, Peng G
- KMID: 2547317
- Korean J Physiol Pharmacol.
- 2023 Nov;27(6):513-520.
- doi: 10.4196/kjpp.2023.27.6.513
Cornuside is a secoiridoid glucoside compound extracted from the fruits of Cornus officinalis. Cornuside has immunomodulatory and anti-inflammatory properties; however, its potential therapeutic effects on diabetic nephropathy (DN) have not... -
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- Effects of aging on accompanying intermittent hypoxia in a bleomycin-induced pulmonary fibrosis mouse model
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Lee H, Kim IK, Im J, Jin BS, Kim HH, Kim SW, Yeo CD, Lee SH
- KMID: 2547651
- Korean J Intern Med.
- 2023 Nov;38(6):934-944.
- doi: 10.3904/kjim.2023.090
Background/Aims: Obstructive sleep apnea (OSA) is prevalent in older patients with idiopathic pulmonary fibrosis (IPF); however, it is underrecognized. OSA is characterized by intermittent hypoxia (IH) and sleep fragmentation. In... -
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- Neutrophil to Lymphocyte Ratio and Serum Biomarkers : A Potential Tool for Prediction of Clinically Relevant Cerebral Vasospasm after Aneurysmal Subarachnoid Hemorrhage
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Kula O, Günay B, Kayabaş MY, Aktürk Y, Kula E, Tütüncüler B, Süt N, Solak S
- KMID: 2547462
- J Korean Neurosurg Soc.
- 2023 Nov;66(6):681-689.
- doi: 10.3340/jkns.2023.0157
Objective : Subarachnoid hemorrhage (SAH) is a condition characterized by bleeding in the subarachnoid space, often resulting from the rupture of a cerebral aneurysm. Delayed cerebral ischemia caused by vasospasm... -
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- Regenerative Treatment with Extracellular Vesicles for Spinal Cord Injury
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Park WT, Lim YJ, Lee GW
- KMID: 2546999
- J Korean Orthop Assoc.
- 2023 Oct;58(5):374-383.
- doi: 10.4055/jkoa.2023.58.5.374
A spinal cord injury (SCI) is a serious condition and can cause permanent disability with a substantial loss of nerve functions (e.g., motor, sensory, etc.). SCI is associated with a... -
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- Helicobacter pylori-associated Chronic Atrophic Gastritis and Progression of Gastric Carcinogenesis
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Lim NR, Chung WC
- KMID: 2547287
- Korean J Gastroenterol.
- 2023 Oct;82(4):171-179.
- doi: 10.4166/kjg.2023.097
Chronic inflammation due to a Helicobacter pylori (H. pylori) infection is a representative cause of gastric cancer that can promote gastric carcinogenesis by abnormally activating immune cells and increasing the... -
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- Neuroplastic and Pro-cognitive Effects of Granulocyte Colony Stimulating Factor in Healthy Adults: A Pilot Study
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Wang SM, Kang DW, Kim HJ, Park SS, Lim HK
- KMID: 2547274
- Psychiatry Investig.
- 2023 Oct;20(10):984-990.
- doi: 10.30773/pi.2023.0150
Objective Granulocyte colony-stimulating factor (G-CSF) is a growth factor used to regulate the mobilization of bone marrow progenitor cells and has been shown to promote brain repair and reduce inflammation.... -
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- The Impact of Taurine on Obesity-Induced Diabetes Mellitus: Mechanisms Underlying Its Effect
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Ahmed K, Choi HN, Yim JE
- KMID: 2546979
- Endocrinol Metab.
- 2023 Oct;38(5):482-492.
- doi: 10.3803/EnM.2023.1776
This review explores the potential benefits of taurine in ameliorating the metabolic disorders of obesity and type 2 diabetes (T2D), highlighting the factors that bridge these associations. Relevant articles and... -
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- Antioxidant and anti-inflammatory effects and mechanism of Abeliophyllum distichum leaf extract in RAW264.7 macrophages
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Yoo J, Kim KA
- KMID: 2547712
- J Nutr Health.
- 2023 Oct;56(5):455-468.
- doi: 10.4163/jnh.2023.56.5.455
Purpose: Abeliophyllum distichum (A.distichum) is a plant native to Korea. In this study, we investigated the mechanism of antioxidant and anti-inflammatory effects of the leaf extract of A.distichum. Methods: The antioxidant... -
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- pH/Temperature Responsive Curcumin-Loaded Micelle Nanoparticles Promote Functional Repair after Spinal Cord Injury in Rats via Modulation of Inflammation
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Qian T, Li Z, Shang L, Huang S, Li G, Zheng W, Mao Y
- KMID: 2546838
- Tissue Eng Regen Med.
- 2023 Oct;20(6):879-892.
- doi: 10.1007/s13770-023-00567-4
BACKGROUND: The formation of an inhibitory inflammatory microenvironment after spinal cord injury (SCI) remains a great challenge for nerve regeneration. The poor local microenvironment exacerbates nerve cell death; therefore, the... -
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- Short-term Efficacy and Safety of Intravitreal Brolucizumab Injection for Treatment-Naive Exudate Age-related Macular Degeneration: A Multicenter Study
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Kim J, Lee SJ, Park TK, Sun HJ, Kim HD, Cho IH, Han JW, Choi KS
- KMID: 2546487
- Korean J Ophthalmol.
- 2023 Oct;37(5):365-372.
- doi: 10.3341/kjo.2023.0009
Purpose: To compare short-term efficacy and safety of intravitreal brolucizumab injection with aflibercept in treatment-naive neovascular age-related macular degeneration (nAMD) patients. Methods: A total of 59 eyes from 59 treatment-naive nAMD... -
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- Neuroprotective effects of hesperetin on H 2 O 2 -induced damage in neuroblastoma SH-SY5Y cells
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Moon HR, Yun JM
- KMID: 2546947
- Nutr Res Pract.
- 2023 Oct;17(5):899-916.
- doi: 10.4162/nrp.2023.17.5.899
BACKGROUND/OBJECTIVES: Oxidative stress is a fundamental neurodegenerative disease trigger that damages and decimates nerve cells. Neurodegenerative diseases are chronic central nervous system disorders that progress and result from neuronal degradation... -
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- Systemic autoinflammatory disorders
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Jeong DC
- KMID: 2546367
- Clin Exp Pediatr.
- 2023 Oct;66(10):432-438.
- doi: 10.3345/cep.2022.01186
Inflammation is a physiologic defense mechanism against an out-side attack. Usually, it resolves after the removal of noxious causes, but systemic autoinflammatory disorders (SAIDs) have recurrent or repeated acute inflammation... -
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- Effects of Pogonatherum paniceum (Lamk) Hack extract on antimitochondrial DNA mediated inflammation by attenuating Tlr9 expression in LPS-induced macrophages
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Thongboontho R, Petcharat K, Munkong N, Khonthun C, Boondech A, Phromnoi K, Thim-uam A
- KMID: 2546942
- Nutr Res Pract.
- 2023 Oct;17(5):827-843.
- doi: 10.4162/nrp.2023.17.5.827
BACKGROUND/OBJECTIVES: Mitochondrial DNA leakage leads to inflammatory responses via endosome activation. This study aims to evaluate whether the perennial grass water extract (Pogonatherum paniceum) ameliorate mitochondrial DNA (mtDNA) leakage. MATERIALS/METHODS: The... -
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- Microbiological links between periodontitis and systemic diseases: a brief review
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Lee SW
- KMID: 2546565
- Oral Biol Res.
- 2023 Sep;47(3):81-94.
- doi: 10.21851/obr.47.03.202309.81
Recent studies have suggested a strong association between chronic periodontitis and various chronic systemic diseases (condition), such as cardiovascular disease, diabetes, respiratory disease, adverse pregnancy outcomes, rheumatoid arthritis, certain types... -
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- Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management
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Amini MA, Karbasi A, Vahabirad M, Khanaghaei M, Alizamir A
- KMID: 2546532
- Chonnam Med J.
- 2023 Sep;59(3):143-159.
- doi: 10.4068/cmj.2023.59.3.143
One of the most complicated eye disorders is age-related macular degeneration (AMD) which is the leading cause of irremediable blindness all over the world in the elderly. AMD is classified as... -
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- Association between periodontal diseases and bipolar disorder: implications for therapeutic interventions: A narrative review
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Baek JH, Jung SJ, Peters A, Kantarci A, Nierenberg AA
- KMID: 2546115
- Precis Future Med.
- 2023 Sep;7(3):117-122.
- doi: 10.23838/pfm.2023.00086
Chronic low-grade inflammation plays a role in the pathophysiology of bipolar disorder. Recent studies have shown that periodontitis can affect the central nervous system by activating inflammatory mediators in the... -
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- C-Reactive Protein Signaling Pathways in Tumor Progression
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Kim ES, Kim SY, Moon A
- KMID: 2545705
- Biomol Ther.
- 2023 Sep;31(5):473-483.
- doi: 10.4062/biomolther.2023.132
Many cancers arise from sites of chronic inflammation, which creates an inflammatory microenvironment surrounding the tumor. Inflammatory substances secreted by cells in the inflammatory environment can induce the proliferation and... -
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- Delta neutrophil index in obese and non-obese polycystic ovary syndrome patients
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Günday , Yılmazer M
- KMID: 2545890
- Obstet Gynecol Sci.
- 2023 Sep;66(5):441-448.
- doi: 10.5468/ogs.22310
Objective We aimed to evaluate the usefulness of delta neutrophil index (DNI), a new inflammatory marker, in polycystic ovary syndrome (PCOS). Methods This retrospective case-control study was conducted at a tertiary... -
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- Omega-3 fatty acids upregulate Nrf2 expression and attenuate apoptosis, inflammation, and fibrosis in a rat model of cyclosporine-induced nephropathy
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Lee JY, Son YK, Lee MH, Lee SM, Kim SE, An WS
- KMID: 2546153
- Kosin Med J.
- 2023 Sep;38(3):184-192.
- doi: 10.7180/kmj.23.112
Background: Cyclosporine A (CsA)-induced kidney injury is characterized by renal impairment with inflammatory cell infiltrations, apoptosis, fibrosis, and hypoxic injury. It is not clear whether omega-3 fatty acids (O-3 FAs),... -
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