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Screening of Plant-Derived Natural Extracts to Identify a Candidate Extract Capable of Enhancing Lipid Synthesis in Keratinocytes

Lee SH, Seo HS, Seo SJ, Kim CD, Hong SP

Background: Reduced lipid content in the stratum corneum is a major cause of skin-barrier dysfunction in various pathological conditions. Promoting lipid production is a potential strategy to improve skin-barrier function....
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Melia azedarach extract exhibits a broad spectrum of antiviral effect in vitro and in vivo

Nethmini NAN, Kim MS, Chathuranga K, Ma JY, Kim H, Lee JS

Melia azedarach is commonly used in traditional and folk medicine in Korea and China to treat a variety of diseases including diarrheal, diabetic, rheumatic, and hypertensive disease. The aim of...
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Drug-induced liver injury

Suh JI

Drug-induced liver injury (DILI), including herbal and dietary supplement hepatotoxicity, is often passed lightly; however, it can lead to the requirement of a liver transplant or may even cause death...
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HL301 in the treatment of acute bronchitis: a phase 2b, randomized, double-blind, placebocontrolled, multicenter study

Yoon SW, Park MJ, Rhee CK, Park JH, Lee SY, Kim DJ, Kim DG, Kim JY

Background/Aims: There is insufficient quality data to recommend the use of herbs for the treatment of acute bronchitis. Small number of randomized trials of plant extracts for this purpose were...
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Intravenous lipid emulsion therapy for cardiac arrest and refractory ventricular tachycardia due to multiple herb intoxication

Han S, Lim H, Noh H

Herbal products have been used for therapeutic purposes for a long time. However, many herbs can be toxic and even life-threatening. If refractory ventricular tachycardia (VT) is caused by herbal...
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RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells

Kang MG, Park D, Han HY, Shim H, Hong Y, Moon J, Yoon S, Kwon B

BACKGROUND: Androgenic alopecia (AGA) is the most common type of hair loss. It is likely inherited genetically and is promoted by dihydrotestosterone. 5α-reductase has been proven a good target through...
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Quantitative Analysis of Metal Contents in Korean Herbs and Herbal Products to Give Advice for Metal Allergic Patient

Choi MJ, Byun JY, Choi HY, Choi YW

BACKGROUND: Herbs have been used worldwide as complementary and alternative medicines. In Korea, herbs for medical purpose are strictly controlled by the Korea Food and Drug Administration (KFDA). But it...
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Medicinal Herbs Effective Against Atherosclerosis: Classification According to Mechanism of Action

Kim JY, Shim SH

Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes of death worldwide. It is caused by the deposition of cholesterol,...
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Effect of herbal extracts on bone regeneration in a rat calvaria defect model and screening system

Lee DH, Kim IK, Cho HY, Seo JH, Jang JM, Kim J

OBJECTIVES: The aim of this study was to evaluate the effects of herbal extracts on bone regeneration. Two known samples were screened. MATERIALS AND METHODS: We previously established a rat calvaria...
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Yield, Nutritional Content, and Antioxidant Activity of Pleurotus ostreatus on Corncobs Supplemented with Herb Residues

Jin Z, Li Y, Ren J, Qin N

Improper disposal of herb residues in China has caused severe problems to the surrounding environment and human safety. Three herb residues, i.e., compound Kushen injection residues (CKI) and part one...
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Icaritin, a Flavonoid Derived from the Herb Epimedium, Promotes Osteogenic Differentiation of MC3T3-E1 Cells

Park DB, Lee HS, Ko SH

Osteoporosis is a metabolic bone disease that is characterized by low bone mass resulting from an increase in bone resorption relative to bone formation. The most current therapies for osteoporosis...
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Distributions of Listeria spp., Bacillus spp., Enterococcus spp., Staphylococcus spp., and Coliforms Isolated from Agricultural Herb Products from the Market

Ham H

The study was conducted to investigate the distribution of pathogenic bacteria related to agricultural herb products that are sold on the market in South Korea. A survey was conducted on...
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From Woohwang Cheongsimwon (牛黃淸心元) to Ginseng (人蔘): The History of Medicine Use in the Joseon Era

KIM SS

In Korean traditional medicine, though herbal decoction, acupuncture, and moxibustion are all used to treat diseases, restorative medicines are the most widely preferred treatment method. This paper explores the historical...
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The effect of Korean traditional alternative medicine products on thyroid function level in post-total thyroidectomy patients: A pilot study

Lee JH, Chung YS, Lee YD

PURPOSE: Although many Koreans consume traditional alternative remedial products to alleviate symptoms of fatigue, there have been no studies on their effect on thyroid function levels in thyroidectomized patients on...
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Decreased absorption of midazolam in the stomach due to low pH induced by co-administration of Banha-sasim-tang

Jo JH, Kim SJ, Nam WS, Seung EJ, Lee S

OBJECTIVES: Banha-sasim-tang (BST), which consists of seven different herbs, is one of the most popular herbal formulae for treating gastrointestinal disorders in Eastern Asia. The commonly used herbal medicine is...
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Effects of multiple herb formula SEC-22 supplementation on dietary intake, picky eating behaviors, and growth indices in thin preschool children

Kim K, Lee J, Paik HY, Yoon J, Ryu B, Shim JE

BACKGROUND/OBJECTIVES: Thin children may have insufficient intake of energy and nutrients, resulting in reduced immune function and growth. This study aimed to identify the effects of multiple herb formula SEC-22...
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Effect of water extract and distillate from the mixture of black goat meat and medicinal herb on osteoblast proliferation and osteoclast formation

Song HN, Leem KH, Kwun IS

PURPOSE: The effects of water extract and distillate from the mixture of black goat meat and medicinal herb on MG-63 osteoblast proliferation and mouse bone marrow derived osteoclast formation were...
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A 14-Day Repeated Dose Toxicity of Epimedii Herba Aqueous Extract Administered by Oral Gavage in F344 Rats

Han HY, Yang YS, Kim SN, Han SC, Han KH, Lee JH, Jeong JY, Roh HS, Seok JH, Kim JA, Min BS

The objective of this study is to characterize a toxicity of Epimedii Herba (EH) in F344 rats and to find a dose levels for the 13 weeks toxicity study. EH...
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A Case of Arisaematis Rhizoma Poisoning

Park S, Yeom S, Han S, Lee S, Ju S

Due to increasing participation in outdoor activities, many people visit the emergency room for various symptoms after mistaking poisonous plants for medicinal herbs. The toxicity of Arisaematis rhizome is due...
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Determination of Cyanogenic Compounds in Edible Plants by Ion Chromatography

Cho HJ, Do BK, Shim SM, Kwon H, Lee DH, Nah AH, Choi YJ, Lee SY

  • KMID: 2317828
  • Toxicol Res.
  • 2013 Jun;29(2):143-147.
Cyanogenic glycosides are HCN-producing phytotoxins; HCN is a powerful and a rapidly acting poison. It is not difficult to find plants containing these compounds in the food supply and/or in...
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