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Development of a Novel Flow Cytometry-Based System for White Blood Cell Differential Counts: 10-color LeukoDiff

Park D, Chang J, Kahng J, Park H, Jo I, Kim Y, Han K

BACKGROUND: Flow cytometry (FCM) is commonly used to identify many cell populations. We developed a white blood cell (WBC) differential counting system for detecting abnormal cells using FCM incorporating 10...
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Dapsone modulates lipopolysaccharide-activated bone marrow cells by inducing cell death and down-regulating tumor necrosis factor-α production

Kwon MJ, Joo HG

Dapsone, an antibiotic, has been used to cure leprosy. It has been reported that dapsone has anti-inflammatory activity in hosts; however, the anti-inflammatory mechanism of dapsone has not been fully...
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Validation of Immature Granulocyte as a Predictor for the 28-Day Mortality in Patients with Severe Sepsis and Septic Shock

Ko YS, Ha SO, Jeong R, Choi B

  • KMID: 2333820
  • J Korean Soc Emerg Med.
  • 2014 Apr;25(2):167-173.
PURPOSE: Recently, several studies for immature granulocyte proportion (IG%) in patients with sepsis have revealed its association with diagnosis and prognosis of patients with sepsis. In this study, we enrolled...
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Usefulness of Delta Neutrophil Index in Prediction of Septic Shock in Patients with Community-acquired Pneumonia

Joo Y, Rhee NG, Kim HJ, You JS, Chung HS, Chung SP, Lee HS, Lee JW

  • KMID: 2333315
  • J Korean Soc Emerg Med.
  • 2013 Apr;24(2):181-187.
PURPOSE: The delta neutrophil index (DNI) corresponds to the calculated immature granulocyte counts and the severity of sepsis. The aim of this study was to investigate the diagnostic value of...
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Assessment of Perforation of Acute Appendicitis using the Delta Neutrophil Index Reflecting Peripheral Immature Granulocyte Count

Rhee NG, Kim MJ, Kim HJ, Chung SP, Lee HS, Lee JW

  • KMID: 2192129
  • J Korean Soc Emerg Med.
  • 2012 Jun;23(3):389-393.
PURPOSE: The delta neutrophil index corresponds to calculated immature granulocyte counts and severity of sepsis. This study was conducted in order to investigate the diagnostic value of the delta neutrophil...
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CKbeta8-1 alters expression of cyclin E in colony forming units-granulocyte macrophage (CFU-GM) lineage from human cord blood CD34 + cells

Noh EK, Ra JS, Lee SA, Kwon BS, Han IS

  • KMID: 1116207
  • Exp Mol Med.
  • 2005 Dec;37(6):619-623.
A C6 beta-chemokine, CKbeta8-1, suppressed the colony formation of CD34 + cells of human cord blood (CB). Molecular mechanisms involved in CKbeta8-1-medicated suppression of colony formation of CD34 + cells...
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Oxidized LDL is a Chemoattractant for the Eosinophils and Neutrophils

Hwang YS, Lee JD, Busse WB

BACKGROUND: Rhinovirus infection of the airways results in increased permeability of the airway vascular endothelium with the influx of plasma proteins, including lipids such as LDL. In vitro studies on...
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The Effect of rhG-CSF and rhGM-CSF on Expression of Fc gamma Receptors and beta2 Integrin and Respiratory Burst Function in Human Granulocytes

Kim KH, Ryu KH, Seoh JY

  • KMID: 2335525
  • J Korean Pediatr Soc.
  • 2001 Apr;44(4):397-404.
PURPOSE: Receptors for the Fc of IgG(FcvR) and a beta2 integrin molecule, CD11c/CD18 are important in clearance of microbes by granulocytes. We performed an in vitro study on the effect...
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The Expression of Fcgamma Receptors in Cord and Adult Blood Granulocytes

Kim KH, Kim GH, Seoh JY, Park HK

  • KMID: 1554065
  • J Korean Pediatr Soc.
  • 1997 Jun;40(6):794-800.
PURPOSE: The immature neonatal immune system is thought to result in increased risk of infection. Receptors for the Fc moiety of IgG (FcgammaR) are important in antibody-mediated clearance of microbes...
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