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The Efficacy and Safety of Cynanchum atratum Root Extract with Containing Moisturizer on Skin Barrier Function and Itch Relief

Joh HC, Park JS, Lee WS, Kim NK, Jue MS, Kim H, Ko JY

  • KMID: 2548457
  • Korean J Dermatol.
  • 2023 Nov;61(9):536-545.
Background: Patients with skin barrier dysfunction often coincides with pruritus, creating a ‘vicious cycle’ of dry skin and itching. Recently, Cynanchum atratum (CA) extract and its constituents have demonstrated effects...
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Biochemical and histopathological changes in livers of rats poisoned with aluminum phosphide and treated with carrot extract

Al-Safar AHA, Jawad RAM, Khayoon HA, Alsaadawi MA, Zenad KH, Saeed ZF, Alkhaled MJ

The experimental studies of Aluminum Phosphide (AP) poisoning in rats revealed several clinical and pathological signs such as hemorrhage, sinusoidal dilatation, bile stasis, centrilobular necrosis, Kupffer cell hyperplasia, infiltration by...
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The Suppression Effect of Garcinia Mangostana L. Pericarp Extract on Cerebral Neovascularization in Type 2 Diabetic Mellitus Rats

Mufaiduddin M, Karlowee V, Nindita Y, Muniroh M

Mangosteen peel extract is a xanthone group, that plays an important role in anti-angiogenesis. This study investigated mangosteen peel extract on cerebral neovascularization in type 2 diabetes mellitus (DM) rats....
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Korean Ginseng Berry Extract Enhances the Male Steroidogenesis Enzymes In Vitro and In Vivo

Chung HJ, Lee SJ, Jang A, Lee CE, Lee DW, Myung SC, Kim JW

Purpose Testosterone hormonal replacement is the most commonly prescribed solution for men with reproductive issues; however, this treatment has various drawbacks. Hence, the identification of a natural product that promotes steroidogenesis...
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Quisqualis indica extract for men with lower urinary tract symptoms: A randomized, double-blind, placebo-controlled trial

Shin D, Zhu GQ, Tian WJ, Ahn ST, Jeon SH, Cho HJ, Ha US, Hong SH, Lee JY, Kim SW, Moon DG, Bae WJ

Purpose: To evaluate the efficacy and safety of Quisqualis indica in men with moderate lower urinary tract symptoms (LUTS). Materials and Methods: A total of 135 subjects with International Prostate Symptom...
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Effects of PB203 on the skin photoaging of ultraviolet B (UVB)-irradiated hairless mice and human keratinocytes

Ho SH, Kim D, Shin Y, Lee JO, Kim YJ, Lee JM, Jang Y, Park SJ

Repetitive or excessive exposure to ultraviolet (UV) radiation causes oxidative stress-mediated skin photoaging through the overproduction of reactive oxygen species. Actinidia polygama is known as a medical plant used in...
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Enhancing the Effect of Placental Extract on the Regeneration of Crush Injured Facial Nerve

Lim GM, Cho GW, Ganesan CD, Choi JH, Ang MJ, Moon C, Jang CH

  • KMID: 2537961
  • Exp Neurobiol.
  • 2022 Dec;31(6):419-430.
  • doi: 10.5607/en22006
There is a scarcity of experimental studies on peripheral nerve regeneration using placental extract (PE). This study aimed to investigate the effects of topical PE application on recovery after crush...
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Antibacterial effect of biodegradable gelatin methacryloyl loaded with ginger rhizome extract

Arbizú-Trigueros RG, Kim SY, Kim YK, Jang YS, Choi AJ, Bae TS, Lee MH

Gelatin methacryloyl 3d mesh mimics the natural extracellular matrix which allow loading as promising drug delivery systems. However, insufficient mechanical and degradation properties remain the biggest obstacle for this material application....
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Antimicrobial effects of green tea extract-containing dentifrice

You EJ, Cho JW, Yoo HJ, Yea JS

Objectives: This study aimed to evaluate the antibacterial activity of green tea extract containing dentifrice on oral disease-causing bacteria. Methods: The antibacterial activity of green tea extract containing dentifrice was examined...
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Mulberry (Morus alba L.) ethanol extract attenuates lipid metabolic disturbance and adipokine imbalance in high-fat fed rats

Noh Dj, Yoon GA

BACKGROUND/OBJECTIVES: An imbalanced adipokine profile in obesity increases the susceptibility to obesity-related cardiometabolic alterations, including type 2 diabetes, hypertension, dyslipidemia, and non-alcoholic fatty liver disease. The mulberry plant has been...
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Evaluation of Anti-cancer and Anti-proliferative Activity of Medicinal Plant Extracts (Saffron, Green Tea, Clove, Fenugreek) on Toll Like Receptors Pathway

Ajmal S, Shafqat M, Ajmal L, Younas H, Tasadduq R, Mahmood N

Despite considerable efforts, cancer remains an aggressive killer worldwide. Chemotherapeutic drugs that are currently in use lead to destructive side effects and have not succeeded in fulfilling expectations. For centuries,...
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Effects of Shiitake mushroom extract on antimicrobial activity against periodontopathogens and inflammatory condition of human gingival fibroblast

Jeon YM

Purpose: The purpose of this study was to investigate antimicrobial activity of extracts from shiitake mushroom against periodontopathogens and its cytotoxicity for human gingival fibroblast. Materials and Methods: Shiitake mushroom...
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Effects of <10-μm Particulate Matter on Cultured Human Sebocytes and Outer Root Sheath Cells and Usefulness of Siegesbeckia Herba Extract

Kwack MH, Ha NG, Lee WJ

Background: Particulate matter (PM) is one of the air pollutants that can damage human skin; the recent increase in the amount of PM may be detrimental to skin health. Objective: We...
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Anticoccidial effects of the Houttuynia cordata extract on experimental animal infection model

Lee HS, Kim O

Coccidiosis is caused by infection of Eimeria species and an significant parasitic disease in poultry. Various kinds of natural products have been studied to find alternative treatments for coccidiosis in...
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Machine learning-based risk factor analysis for periodontal disease from a Korean National Survey

Shon HS, Choi ES, Cho YS, Cha EJ, Kang TG, Kim KA

Periodontal disease is a chronic but treatable condition which often does not cause pain during the initial stages of the illness. Lack of awareness of symptoms can delay initiation of...
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Enhancing the Angiogenic and Proliferative Capacity of Dermal Fibroblasts with Mulberry ( Morus alba. L) Root Extract

Im J, Hyun J, Kim SW, Bhang SH

BACKGROUND: Enhancing blood flow and cell proliferation in the hair dermis is critical for treating hair loss. This study was designed to aid the development of alternative and effective solutions...
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Steamed Ginger Extract Exerts Anti-inflammatory Effects in Helicobacter pylori-infected Gastric Epithelial Cells through Inhibition of NF-κB

Song MY, Lee DY, Park SY, Seo SA, Hwang J, Heo SH, Kim EH

Ginger (Zingiber officinale) has traditionally been used as a treatment for inflammatory diseases in the Asian region. Recently, anti-inflammatory effects of steamed ginger extract (GGE03) have been reported, but its...
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Effects of Amniotic Membrane Extract Eye Drops on Persistent Epithelial Defects of the Cornea

Nam JW, Kim J, Yoon HJ, Yoon KC

Purpose: To evaluate the clinical efficacy of amniotic membrane extract eye drops (AMEEDs) in patients with persistent epithelial defects (PEDs) of the cornea. Methods: Sixteen patients with PEDs refractory to the...
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Preventive effects of shiitake mushroom extract on candida stomatitis

Yoo HJ

Purpose: The purpose of this study was to investigate antifungal activity of shiitake mushroom yeast and hyphal type of Candida albicans. Materials and Methods: The extract from shiitake mushroom was...
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Osteoblast cytocompatibility and antibacterial effect of ginger main compounds

Arbizú-Trigueros RG, Baek YS, Kim SY, Kim YK, Jang YS, Kim TH, Bae TS, Lee MH

Ginger has been used worldwide in traditional medicine. It has been reported that phenolic compounds such as gingerol and shogaol in ginger have beneficial cellular effect and antibacterial effect. The...
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