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Current Challenges for the Early Detection of Alzheimer's Disease: Brain Imaging and CSF Studies

Mistur R, Mosconi L, Santi SD, Guzman M, Li Y, Tsui W, de Leon MJ

The development of prevention therapies for Alzheimer's disease (AD) would greatly benefit from biomarkers that are sensitive to the subtle brain changes that occur in the preclinical stage of the...
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Single Photon Emission Computerized Tomography and Neuropsychological Tests That Predict a Good Response to Donepezil Therapy for Alzheimer's Disease

Kim DE, Chong A, Song HC, Choi SM, Kang KW, Ha JM, Kim JH, Kim TH, Jeong GW, Park KW, de Leon MJ, Kim BC

BACKGROUND AND PURPOSE: Cholinesterase inhibitors (ChEIs) are effective in Alzheimer's disease (AD) treatment. The aim of this study is 1) to find neuropsychological factors that affect the functional response to...
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