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Pharmacological treatment of the patients with croup

Jang YY, Chung HL

Background: Croup is a respiratory illness usually caused by acute viral infection of the larynx, trachea, and bronchi, and characterized by the abrupt onset of a barking cough, inspiratory stridor,...
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Predictive factors for achievement of mucosal healing by budesonide 2-mg foam in ulcerative colitis: a pooled analysis of data from two clinical trials

Hibi T, Naganuma M, Oda E, Yamada Y, Chujoh Y, Yoshihara , Watanabe M

Background/Aims: Mucosal healing (MH) of distal lesions in ulcerative colitis (UC) has recently been confirmed with budesonide 2-mg foam (BF) treatment in 2 clinical trials; however, few studies have investigated...
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Real-Life Clinical Use of Symbicort® Maintenance and Reliever Therapy for Asthmatic Patients in Korea

Kim SH, Kim TB, Kim SH, Park HW, Song SH, Jeong JW, Jee YK, Park SW, Kim MS, Yoon HJ

The aim of this study was to examine the daily practice patterns of Symbicort® Maintenance and Reliever Therapy (SMART) in Korean asthmatic patients and to analyze clinical signs related to...
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The Effectiveness of Budesonide Nasal Irrigation After Endoscopic Sinus Surgery in Chronic Rhinosinusitis With Asthma

Kang TW, Chung JH, Cho SH, Lee SH, Kim KR, Jeong JH

OBJECTIVES: Budesonide nasal irrigation was introduced recently for postoperative management of patients with chronic rhinosinusitis. The safety and therapeutic effectiveness of this procedure is becoming accepted by many physicians. The...
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Mometasone Furoate Suppresses PMA-Induced MUC-5AC and MUC-2 Production in Human Airway Epithelial Cells

Poachanukoon O, Koontongkaew S, Monthanapisut P, Pattanacharoenchai N

BACKGROUND: Mucus hypersecretion from airway epithelium is a characteristic feature of airway inflammatory diseases. Tumor necrosis factor α (TNF-α) regulates mucin synthesis. Glucocorticoids including mometasone fuorate (MF) have been used...
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A Case of Esophageal Candidiasis in an Adolescent Who Had Frequently Received Budesonide Nebulizing Therapy

Kang HR, Kwon YH, Kim YJ

Corticosteroid (budesonide) nebulizer therapy is commonly performed. Its side effects have been considered as being safe or ignorable. The authors present a case of esophageal candidiasis in a healthy female...
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The Combination of Tiotropium and Budesonide in the Treatment of Chronic Obstructive Pulmonary Disease

Um SW, Yoo CG, Kim YW, Han SK, Shim YS

Because additive effects of inhaled corticosteroids and long-acting anticholinergics are unclear, we undertook this study to compare the efficacy of tiotropium alone and tiotropium plus budesonide in patients with chronic...
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Vasoactive Intestinal Peptide Induces MUC2/5AC Synthesis in Human Airway Epithelial Cells

Kim YD, Chang KY, Sin JH, Kwak DS, Lee HJ, Song SY, Song KW

  • KMID: 2074510
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Jul;47(7):639-644.
BACKGROUND AND OBJECTIVES: Vasointestinal peptide (VIP) is an important neurotransmitter involved in the regulation of mucus secretion, but the relationship of VIP and mucin genes is not clear. This study...
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Budesonide Down-regulates IL-1beta-Mediated MUC2/MUC5AC Genes Expression and Mucin Secretion in Human Airway Epithelial Cells

Kim YD, Cho JS, Chang KY, Sin JH, Song SY, Yoon SK

  • KMID: 2141380
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Sep;45(9):873-877.
BACKGROUND AND OBJECTIVES: Mucus hypersecretion is a hallmark of many respiratory inflammatory diseases such as asthma, bronchitis and sinusitis. While the current therapeutic pharmacological approaches to reducing mucus hypersecretion are...
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Clinical Validation of Nebulized Budesonide and Effect of Nebulized Budesonide on the Hypothalamic-Pituitary-Adrenal Axis in Adult Patients Admitted with Acute Asthmatic Attack

Seo KH, Moon SH, Kim YH

  • KMID: 2318384
  • Tuberc Respir Dis.
  • 2002 May;52(5):529-538.
BACKGROUND: Many clinicians are reluctant to prescribe systemic corticosteroids to manage and asthmatic attack because of many complications such as osteoporosis, cushing's syndrome, diabetes, hypertension and blee ding tendency. The...
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A comparative study of intranasal budesonide and oral terfenadine in perennial allergic rhinitics: effect on the symptom score and nasal secretion eosinophils

Lee BJ, Kim YJ, Kim JH, Shin HS, Chung YS

  • KMID: 2285958
  • J Asthma Allergy Clin Immunol.
  • 2001 Apr;21(2):216-222.
BACKGROUND: Eosinophilia in the nasal secretion and mucosal tissues is the characteristic finding of allergic rhinitis. We compared the effects of nasal budesonide dipropionate and oral terfenadine on the symptom...
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A Case of Atopic Dermatitis with Egg and Budesonide Hypersensitivity

Kim HW, Kim GI, Park CW, Lee CH

  • KMID: 2250979
  • Korean J Dermatol.
  • 2001 Nov;39(11):1286-1289.
The egg is one of the most common food allergens, and immunologic reactivity to egg antigens may be an early marker of atopic disorders. Budesonide is a synthetic non-halogenated corticosteroid...
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Short-term Effects of Inhaled Corticosteroid Following Early Systemic Corticosteroid Administration in Premature Babies with Respiratory Distress Syndrome: A Preliminary Report

Lee HS

  • KMID: 2207457
  • J Korean Pediatr Soc.
  • 2000 Nov;43(11):1440-1445.
PURPOSE: To asses the short-term effects of the topical corticosteroid, budesonide administered by metered dose inhaler(MDI) and spacer(Aerochamber MV 15) following systemic corticosteroid in premature babies with respiratory distress syndrome at birth....
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The difference of interieukin - 4 and interferon - r production of Der p I stimulated T cells and effects of immunomodulator in house dust mite sensitive atopic and non - atopic individuals

Oh JW, Lee HB, Chung YH, Choi Y, Song MK

  • KMID: 2054841
  • J Asthma Allergy Clin Immunol.
  • 1999 Aug;19(4):548-556.
BACKGROUND: Allergic diseases are characterized by immediate - and late - phase reactions to various allergens by the selective activation of a subset of CD4 + T cells. In response...
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Prospective Randomized Study Comparing L-epinephrine and Budesonide Aerosols in the Treatment of Moderate to Severe Croup

Choi BH, Song KB, Shim JY, Hong SJ

  • KMID: 1946322
  • J Korean Pediatr Soc.
  • 1999 Jan;42(1):40-46.
PURPOSE: The aim of this prospective, randomized study was to evaluate the effects and adverse effects of nebulized L-epinephrine compared with nebulized budesonide in children with moderate to severe croup....
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A Comparison of the Therapeutic Effects of Powder and Aerosolized Budesonide in the Treatment of Perennial Allergic Rhinitis

Min YG, Park HJ, Mo JH, Yun JB, Jung IH, Kwon TY

  • KMID: 2131695
  • J Rhinol.
  • 1998 May;5(1):11-14.
The aims of this study are to compare the efficacy and side effects of intranasal budesonide as a dry powder and as a freonpropelled pressurized aerosol in the treatment of...
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The Treatment of Croup with Nebulized Budesonide and Intramuscular Dexamethasone

Lee JW, Rah YH, Bae CW, Chung SJ, Choi YM

  • KMID: 2207971
  • J Korean Pediatr Soc.
  • 1998 Mar;41(3):331-337.
PURPOSE: Steroids have anti-inflammatory effects which reduces inflammation and edema of the tissue. Thus, corticosteroids have been used for treatment of croup. The aim this study is to compare and...
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Beneficial Effects of Inhaled Budesonide on Elevated Circulating Levels of Serum ECP, ICAM-1, VCAM-1, IL-6 and IL-6R in Children with Asthma

Kim JH, Oh JW, Lee HB

  • KMID: 2139032
  • Pediatr Allergy Respir Dis.
  • 1998 Mar;8(1):37-46.
PURPOSE: Allergic inflammation in the airway of asthmatics was characterized by recruitment and activation of inflammatory cells. The recognition of the underlying inflamatory nature of asthma led to suggestions that...
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The Protective Effect of Inhaled Heparin, Cromolyn, Budesonide, and Furosemide on Exercise-induced Asthma

Lee SH, Shim JJ, Lee SY, Cho JY, In KH, Yoo SH, Kang KH

  • KMID: 2318182
  • Tuberc Respir Dis.
  • 1998 Dec;45(6):1188-1198.
BACKGROUND: The purpose of the present study was to determine the protective effect of antiasthmatic activity of inhaled heparin, cromolyn sodium, budesonide, furosemide in exercise-induced asthma(EIA). The other important considerable...
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A Case of Distal Ulcerative Colitis Improved by Budesonide Enemas

Kim YJ, Shin KS, Kim NS, Lee H

  • KMID: 2335393
  • J Korean Pediatr Soc.
  • 1998 Nov;41(11):1610-1613.
A ten-year-old boy presented with chronic diarrhea and rectal bleeding was studied. Colonoscopic and pathologic diagnosis was distal ulcerative colitis in the sigmoid colon and rectum. Budesonide retention enema (2mg/100ml)...
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