- Tacrolimus (FK506) Induced Apoptotic Signal Transduction Pathway
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Jung MR, Choi SJ, Chung SY
- KMID: 2117082
- J Korean Surg Soc.
- 2007 Nov;73(5):359-365.
PURPOSE: This study examined the effects of Tacrolimus (FK506) on the expression of the apoptotic signal transduction proteins of Jurkat human T-lymphocytes. METHODS: The cell viability was examined by a... -
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- The Mechanism of Intracellular Signal Pathway that Baicalin Hydrate Elevate Chemotherapeutic Response of Cervical Carcinoma
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Kim BR, Kim IS, Ko KH, Lee JJ, Kim HG, Park RG
- KMID: 2076936
- Korean J Obstet Gynecol.
- 2003 Oct;46(10):1965-1974.
Baicalin is flavonoid and major component of PC-SPES. Flavonoids including baicalin have been reported to not only function as anti-oxidant but also cause cytotoxic effect. Baicalin hydrate has been reported... -
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- Effect of Rapamycin on the Cell Cycle Arrest of T Lymphocytes
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Lee JS, Han C, Cho SN, Chung SY
- KMID: 2325113
- J Korean Surg Soc.
- 2007 Jul;73(1):13-20.
PURPOSE: Rapamycin (RPM) and its analogues are known for their potent immunosuppressant and anti-proliferative properties, which stem from their ability to modulate the signal transduction pathways involved in cell cycle... -
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- Protective Effects of Oleic Acid Against Palmitic Acid-Induced Apoptosis in Pancreatic AR42J Cells and Its Mechanisms
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Ahn JH, Kim MH, Kwon HJ, Choi SY, Kwon HY
- KMID: 1432762
- Korean J Physiol Pharmacol.
- 2013 Feb;17(1):43-50.
- doi: 10.4196/kjpp.2013.17.1.43
Palmitic acid (PAM), one of the most common saturated fatty acid (SFA) in animals and plants, has been shown to induce apoptosis in exocrine pancreatic AR42J cells. In this study,... -
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- Stimulatory heterotrimeric G protein augments gamma ray-induced apoptosis by up-regulation of Bak expression via CREB and AP-1 in H1299 human lung cancer cells
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Choi YJ, Kim SY, Oh JM, Juhnn YS
- KMID: 1119325
- Exp Mol Med.
- 2009 Aug;41(8):592-600.
- doi: 10.3858/emm.2009.41.8.065
Stimulatory heterotrimeric GTP-binding proteins (Gs protein) stimulate cAMP generation in response to various signals, and modulate various cellular phenomena such as proliferation and apoptosis. This study aimed to investigate the... -
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