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The Global Landscape of Domestic Violence against Women during the COVID-19 Pandemic: A Narrative Review

Kunasagran PD, Mokti K, Ibrahim MY, Rahim SSSA, Robinson F, Muyou AJ, Mujin SM, Ali N, Chao GGC, Nasib R, Loong ACE, Rahim NBA, Ahmad MH, Dhanaraj PS, Arumugam P, Yusoff J

The coronavirus disease (COVID-19) pandemic has led to an alarming increase in domestic violence against women owing to lockdown measures and limited access to support services. This article provides insights...
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Cerebral Cavernous Malformation (CCM)-like Vessel Lesion in the Aged ANKS1A-deficient Brain

Lee J, Lee H, Shin M, Park S

  • KMID: 2550812
  • Exp Neurobiol.
  • 2023 Dec;32(6):441-452.
  • doi: 10.5607/en23032
In this study, we show that ANKS1A is specifically expressed in the brain endothelial cells of adult mice. ANKS1A deficiency in adult mice does not affect the differentiation, growth, or...
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Intrathecal Catheter for Chemotherapy in Leptomeningeal Carcinomatosis From HER2-Negative Metastatic Breast Cancer

Dupoiron D, Autier L, Lebrec N, Seegers V, Folliard C, Patsouris A, Campone M, Augereau P

Purpose: Most oncological treatments for leptomeningeal metastasis (LM) do not cross the blood-brain barrier (BBB). One therapeutic option is intrathecal (IT) chemotherapy. Both the brain-implanted Omaya reservoir and lumbar puncture...
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The Efficacy and Safety of Cynanchum atratum Root Extract with Containing Moisturizer on Skin Barrier Function and Itch Relief

Joh HC, Park JS, Lee WS, Kim NK, Jue MS, Kim H, Ko JY

  • KMID: 2548457
  • Korean J Dermatol.
  • 2023 Nov;61(9):536-545.
Background: Patients with skin barrier dysfunction often coincides with pruritus, creating a ‘vicious cycle’ of dry skin and itching. Recently, Cynanchum atratum (CA) extract and its constituents have demonstrated effects...
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Novel Histone Deacetylase 6 Inhibitor Confers Anti-inflammatory Effects and Enhances Gut Barrier Function

Lee JY, Ma HW, Kim JH, Park IS, Son M, Ryu KH, Shin J, Kim SW, Cheon JH

Background/Aims: The purpose of the current study was to examine the anti-inflammatory effects of CKD-506, a novel histone deacetylase 6 inhibitor, on human peripheral blood mononuclear cells (PBMCs) and CD4+...
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The double-barrier technique using platelet-rich fibrin for closure of oroantral fistulas

Jung JW, Hong So, Lee EJ, Kim RY, Jee YJ

An oroantral fistula (OAF) or oroantral communication (OAC) is an opening between the oral cavity and the maxillary sinus. If left untreated, these openings may cause chronic maxillary sinusitis. Although...
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Impact of Extra-Corporeal Membrane Oxygenation and Blood Purification Therapy on Early Mobilization in the Intensive Care Unit: Retrospective Cohort Study

Watanabe S, Iida Y, Hirasawa J, Naito Y, Mizutani M, Uemura A, Nishimura S, Suzuki K, Morita Y

Objective: To investigate the effect on early mobilization in patients undergoing extra-corporeal membrane oxygenation (ECMO) and acute blood purification therapy in the intensive care unit (ICU). Methods: We conducted this multicenter...
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Impact of the Junction Adhesion MoleculeA on Asthma

An MH, Lee PH, Choi SM, Hwang D, Kim JH, Park MC, Park S, Baek AR, Jang AS

Purpose: Junctional adhesion molecule (JAM)-A is an immunoglobulin-like molecule that colocalizes with tight junctions (TJs) in the endothelium and epithelium. It is also found in blood leukocytes and platelets. The...
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Practical issues in CAR T-cell therapy

Byun JM

Chimeric antigen receptor (CAR) T-cell therapy presents a revolutionary advancement in personalized cancer treatment. During the production process, the patient's own T-cells are genetically engineered to express a synthetic receptor...
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Evaluation of Serum Zonulin and Occludin Levels in Bipolar Disorder

Zengil S, Laloğlu E

Objective The etiology of bipolar disorder (BD) is still not fully understood. Little is currently known about the relationship between the interaction the gastrointestinal system and brain function and BD....
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Healing of the Bony Access Window Without Barrier Membrane Coverage in Lateral Sinus Augmentation: Case Series with 5-27 years of Follow-up

Park WB, Lim HC

In lateral maxillary sinus augmentation (MSA), barrier membrane coverage over the bony access window is a routine practice. Many studies on MSA have demonstrated histologic and radiographic healing...
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Improvement of the intestinal epithelial barrier during laxative effects of phlorotannin in loperamide‑induced constipation of SD rats

Kim J, Song H, Choi Y, Jin Y, Roh Y, Seol A, Park S, Park J, Kang H, Hwang D

Background: Disruptions of the intestinal epithelial barrier (IEB) are frequently observed in various digestive diseases, including irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD). This study assessed the improvement...
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Characteristics of Focused Ultrasound Mediated Blood-Brain Barrier Opening in Magnetic Resonance Images

Chang KW, Hong SW, Chang WS, Jung HH, Chang JW

Objective : The blood-brain barrier (BBB) is an obstacle for molecules to pass through from blood to the brain. Focused ultrasound is a new method which temporarily opens the BBB,...
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The Heart Is at Risk: Understanding Stroke-Heart-Brain Interactions with Focus on Neurogenic Stress Cardiomyopathy—A Review

Ziaka M, Exadaktylos A

In recent years, it has been convincingly demonstrated that acute brain injury may cause severe cardiac complications—such as neurogenic stress cardiomyopathy (NSC), a specific form of takotsubo cardiomyopathy. The pathophysiology...
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Arterial Spin Labelling-Based Blood-Brain Barrier Assessment and Its Applications

Li Y, Sadiq A, Wang Z

The brain relies on the blood-brain barrier (BBB) for the selective absorption of nutrients and the exclusion of other big molecules from the circulating blood. Therefore, the integrity of BBB...
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Therapeutic Approaches Targeting Vascular Repair After Experimental Spinal Cord Injury: A Systematic Review of the Literature

Roolfs L, Hubertus V, Spinnen J, Shopperly LK, Fehlings MG, Vajkoczy P

Traumatic spinal cord injury (SCI) disrupts the spinal cord vasculature resulting in ischemia, amplification of the secondary injury cascade and exacerbation of neural tissue loss. Restoring functional integrity of the...
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Comparison of intracranial pressure changes in out-of-hospital cardiac arrest patients with and without malignant blood-brain barrier disruption

Lee S, You Y, Ahn HJ, Park JS, Jeong W, Kang C, Min JH, In YN

Objective In the present study, intracranial pressure (ICP) changes were investigated in out-ofhospital cardiac arrest (OHCA) patients with and without malignant blood-brain barrier (BBB) disruption who underwent target temperature management. Methods...
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Context-Dependent Regulation of Type17 Immunity by Microbiota at the Intestinal Barrier

Akuzum B, Lee JY

T-helper-17 (Th17) cells and related IL-17-producing (type17) lymphocytes are abundant at the epithelial barrier. In response to bacterial and fungal infection, the signature cytokines IL-17A/F and IL-22 mediate the antimicrobial...
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Protective Effect of Nimodipine Against Valproic-acid Induced Biochemical and Behavioral Phenotypes of Autism

Kumar H, Diwan V, Sharma B

Objective: Present study was designed to investigate behavioral and biochemical role of nimodipine in prenatal valproic acid (Pre-VPA) induced autism in rats. Methods: Valproic acid was utilized to induce autistic phenotypes...
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Distribution of Neuroglobin in Pericytes is Associated with Blood-Brain Barrier Leakage against Cerebral Ischemia in Mice

Kim Y, Kim M, Kim SD, Yoon N, Wang X, Bae GU, Song YS

  • KMID: 2535060
  • Exp Neurobiol.
  • 2022 Oct;31(5):289-298.
  • doi: 10.5607/en22001
With emerging data on the various functions of neuroglobin (Ngb), such as neuroprotection and neurogenesis, we investigated the role of Ngb in the neurovascular unit (NVU) of the brain. To...
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