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Effect of a Soothing Cooler on Pruritus in Mild Atopic Dermatitis

Lee EH, Park CI, Lee WJ

  • KMID: 2519514
  • Korean J Dermatol.
  • 2021 Aug;59(7):538-543.
Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease that often results in a severely reduced quality of life due to its irritating symptoms. Cooling the skin can be...
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Case Report of a Pilot with Atopic Dermatitis

Kwon YH

Atopic dermatitis is a condition that makes skin red and itchy. It is common in children but can occur at any age. Atopic dermatitis is chronic and tends to flare...
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Immunohistochemical Analysis of Prurigo Nodularis in 209 Patients: Clinicopathological Analysis between Atopic and Non-Atopic Patients and between Treatment Response Groups

Byun HJ, Jang D, Lee DY, Yang JM

Background: Prurigo nodularis (PN) is a highly pruritic disease that significantly impairs patient quality of life. Although the mechanism that causes pruritus is not clear, one hypothesis argues that neural...
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Influence of age at complementary food introduction on the development of asthma and atopic dermatitis in Korean children aged 1–3 years

Lee J, Shin M, Lee B

Background: Complementary food in infancy is necessary for human growth, neurodevelopment, and health. However, the role of allergen consumption in early infancy and its effects on the development of food...
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A Case of Methicillin-Sensitive Staphylococcus aureus Bacteremia Superimposed on Eczema Herpeticum in a Patient with Uncontrolled Atopic Dermatitis

Lee YS, Kim YS, Lee JH, Choi JE, Han TY

  • KMID: 2518995
  • Korean J Dermatol.
  • 2021 Jul;59(6):491-494.
Eczema herpeticum is a widespread herpes simplex infection that favors eczema-damaged skin, including skin involved with atopic dermatitis. Here we report a case of a 27-year-old woman who presented with...
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A case of canine blepharoconjunctivitis associated with atopic dermatitis

Kim Y, Kim HJ, Kim JH, Lee JH, Kim S, Kim SE, Kim T, Kim HJ

An 8-year-old, spayed female Maltese dog was presented with a one-month history of erythema, swelling and alopecia of periocular region with pruritus. The skin lesions were first detected at the...
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Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin

Jeon SH, Lee YS, Yeo IJ, Lee HP, Yoon J, Son DJ, Han SB, Hong JT

Chitinase-3-like-1 (CHI3L1) is known to induce inflammation in the progression of allergic diseases. Previous our studies revealed that 2-({3-[2-(1-cyclohexen-1-yl)ethyl]-6,7-dimethoxy-4-oxo-3,4-dihydro-2-quinazolinyl}sulfanyl)-N-(4-ethylphenyl)butanamide (K284-6111; K284), the CHI3L1 inhibiting compound, has the anti-inflammatory effect on...
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Participants’ Satisfaction with the Atopic Dermatitis Education Program: Assessing the Impact of Each Content Using Structural Equation Modeling

Ryoo JH, Lee SH, Lee HJ, Park J, Kim SA, Ryoo YW, Shin DH, Suh MK, Kim JY, Park KD, Lee WJ, Lee SJ, Kim DW, Jang YH

Background: Only a few studies have tried to assess factors relevant to the satisfaction of the participants in atopic dermatitis (AD) educational programs. More systematic modeling of this issue is...
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Characteristic Clinical Features of Korean Atopic Dermatitis Patients with Interleukin-17 Receptor A Gene Mutation

Lee JW, Yu K, Lee H, Choi EH

  • KMID: 2516142
  • Korean J Dermatol.
  • 2021 May;59(4):290-295.
Background: Th17 cytokines such as interleukin-17 and interleukin-22 are expressed in atopic dermatitis lesions. Previous studies have reported increased levels of interleukin-17A, -17E, and -17F in patients with atopic dermatitis.As...
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Age Differences in Pet Sensitization by Pet Ownership

Won JY, Kwon JW, Hong SN, Lee WH

Objectives. The association between pet sensitization and pet ownership remains unclear. Therefore, we aimed to elucidate the association between pet sensitization and pet ownership by age. Methods. We retrospectively reviewed 2,883...
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Update on management of pediatric atopic dermatitis

Jeon YH, Kim JH

Atopic dermatitis is the most common chronic inflammatory skin disease in children. It usually develops in infancy and early childhood and is an entry point of ‘atopic march’, which may...
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Dental Caries in Adults with Atopic Dermatitis: A Nationwide Cross-Sectional Study in Korea

Park HJ, Choi M, Park HJ, Haw S

Background: Dental caries is the most prevalent chronic infectious oral disease of multifactorial etiology. Increased risk of dental caries development in patients with asthma and allergic rhinitis has been frequently...
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Therapeutic New Era for Atopic Dermatitis: Part 2. Small Molecules

Ahn J, Choi Y, Simpson EL

Atopic dermatitis (AD) is a chronic, inflammatory cutaneous disease driven by immune dysregulation and skin barrier dysfunction. Currently, we are experiencing a new era of understanding of the pathogenesis of...
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Keratinocytes-Derived Reactive Oxygen Species Play an Active Role to Induce Type 2 Inflammation of the Skin: A Pathogenic Role of Reactive Oxygen Species at the Early Phase of Atopic Dermatitis

Choi DI, Park JH, Choi JY, Piao M, Suh MS, Lee JB, Yun SJ, Lee SC

Background: Atopic dermatitis (AD) is characterized by chronic, relapsing skin inflammation (eczema) with itchy sensation. Keratinocytes, which are located at the outermost part of our body, are supposed to play...
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Therapeutic New Era for Atopic Dermatitis: Part 1.Biologics

Ahn J, Choi Y, Simpson EL

Atopic dermatitis (AD) is a chronic, inflammatory cutaneous disease driven by immune dysregulation and skin barrier dysfunction. We are currently experiencing a new era of understanding of the pathogenesis of...
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Cell Autonomous Circadian Systems and Their Relation to Inflammation

Annamneedi VP, Park JW, Lee GS, Kang TJ

All living beings on earth have an important mechanism of 24-h periodicity, which controls their physiology, metabolism, and behavior. In humans, 24-h periodicity is regulated by the superchiasmatic nucleus (SCN)...
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Data resource profile: the allergic disease database of the Korean National Health Insurance Service

Yoo S, Kim DW, Kim YE, Park JH, Kim YY, Cho Kd, Gwon MJ, Shin JI, Lee EJ

Researchers have been interested in probing how the environmental factors associated with allergic diseases affect the use of medical services. Considering this demand, we have constructed a database, named the...
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Age–period–cohort analysis of asthma, allergic rhinitis, and atopic dermatitis prevalence in Japan

Okui T

This study aims to analyze the trends in the Japanese prevalence of asthma, allergic rhinitis, and atopic dermatitis by using age–period–cohort (APC) analysis. Data regarding the prevalence of diseases from...
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Effect of Weight Reduction on Treatment Outcomes for Patients with Atopic Dermatitis

Jung MJ, Kim HR, Kang SY, Kim HO, Chung BY, Park CW

Background: Several epidemiological studies have shownthat the atopic tendency increases in the obese population. Objective: The aim of this study was to confirm the effect ofweight reduction on improvement of atopic...
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Increased 1-Deoxysphingolipids and Skin BarrierDysfunction in the Skin of X-ray or Ultraviolet BIrradiation and Atopic Dermatitis Lesion Could BePrevented by Moisturizer with Physiological LipidMixture

Chung BY, Kim HO, Kang SY, Jung MJ, Kim SW, Yoo KS, Shin KO, Jeong SK, Park CW

Background: Skin diseases characterized by epithelial barrierdysfunction show altered sphingolipid metabolism,which results in changes in the stratum corneum intercellularlipid components and structure. Under pathological conditions,1-deoxysphingolipids form as atypical sphingolipidsfrom de...
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