- Allergen sensitization trajectories in children with respiratory and allergic diseases
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Jo SW, Jeon S, Lee HS, Kim HM, No YY, Park MR, Jung JH, Kim SY, Kim JD, Kim MJ, Lee YJ, Kim KW, Sohn MH, Kim YH
- KMID: 2538970
- Allergy Asthma Respir Dis.
- 2023 Jan;11(1):34-42.
- doi: 10.4168/aard.2023.11.1.34
Purpose: There is a lack of a report about the trajectories of allergen sensitization, although it is important to understand the change of allergen sensitization to manage allergic disease. This... -
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- Allergic Sensitization Pattern in the Korean Dermatologic Patients
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Han Y, Woo YR, Kim HS, Lee JD, Choi S, Yu J, Cho SH
- KMID: 2536302
- Ann Dermatol.
- 2022 Dec;34(6):431-441.
- doi: 10.5021/ad.21.260
Background: Avoiding causative allergens is important for controlling the clinical course of allergic diseases. Allergen sensitization is influenced by many factors including the environment and lifestyle. The socioeconomic development, climate,... -
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- Development of a house dust mite-induced mouse model for allergen-specific immunotherapy in allergic rhinitis
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Kim SM, Kim JA, Kim HS, Yoon JS, Kim HH, Chun YH
- KMID: 2534606
- Allergy Asthma Respir Dis.
- 2022 Oct;10(4):195-201.
- doi: 10.4168/aard.2022.10.4.195
Purpose: Allergen-specific immunotherapy (AIT) is the only known curative treatment for allergic diseases. Recently, novel immunotherapies have been developed to overcome the inconvenience and adverse reactions associated with conventional AIT.... -
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- Microneedle Transdermal Drug Delivery Systems for Allergen-Specific Immunotherapy, Skin Disease Treatment, and Vaccine Development
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Park CO, Kim HL, Park JW
- KMID: 2533366
- Yonsei Med J.
- 2022 Oct;63(10):881-891.
- doi: 10.3349/ymj.2022.0092
Transdermal drug delivery systems (TDDSs) overcome the hurdle of an intact skin barrier by penetrating the skin to allow molecules through. These systems reduce side effects associated with conventional hypodermic... -
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- Evolution in Allergen Sensitization in Korean Patients with Atopic Dermatitis: A 10-Year Retrospective Study Based on the Multiple Allergen Simultaneous Test
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Han Y, Cho M, Woo YR, Kim HS, Lee JD, Cho SH
- KMID: 2532294
- Korean J Dermatol.
- 2022 Jul;60(6):350-363.
Background: Avoiding causative allergens is important for controlling the clinical course of atopic dermatitis (AD). Allergen sensitization is influenced by many factors, such as the environmental factors. Although socioeconomic development,... -
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- Change in sensitization to inhalant allergens in adults with respiratory allergic disease in Busan and Gyeongsangnam-do province
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Park CS, Jo EJ, Kim M, Nam YH, Lee SE, Choi GS, Jeong YY, Kim HK, Oh JW, Park HK
- KMID: 2532272
- Allergy Asthma Respir Dis.
- 2022 Jul;10(3):172-180.
- doi: 10.4168/aard.2022.10.3.172
Purpose: It is crucial to identify the causative allergen of respiratory allergic disease. Air pollution and climate change affect the allergen concentration as well as the sensitization rate. This study... -
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- Recent Advances in Allergen-Specific Immunotherapy in Humans: A Systematic Review
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Lee SP, Shin YS, Kang SY, Kim TB, Lee SM
- KMID: 2536230
- Immune Netw.
- 2022 Feb;22(1):e12.
- doi: 10.4110/in.2022.22.e12
Allergen-specific immunotherapy (AIT) is presumed to modulate the natural course of allergic disease by inducing immune tolerance. However, conventional AITs, such as subcutaneous immunotherapy and sublingual immunotherapy, require long treatment... -
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- Changes in allergen sensitization in children with allergic diseases in the 1980 to 2019
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Jung JH, Kim GE, Park M, Kim SY, Kim MJ, Lee YJ, Kim YH, Kim KW, Sohn MH
- KMID: 2521770
- Allergy Asthma Respir Dis.
- 2021 Oct;9(4):208-215.
- doi: 10.4168/aard.2021.9.4.208
Purpose: Allergen sensitization is constantly changing, and understanding these changes can help manage and prevent allergic diseases. This research analyzed and compared the changes in allergen sensitization in children diagnosed... -
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- Current Update of Local Allergic Rhinitis
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Kim SJ, Moon JW, Lee HM
- KMID: 2519750
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2021 Aug;64(8):533-539.
- doi: 10.3342/kjorl-hns.2021.00416
Local allergic rhinitis (LAR) is a localized nasal allergic response in the absence of systemic atopy. The symptoms, duration, severity, and comorbidities of LAR are similar to those of allergic... -
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- Comparison of inhalant allergen sensitization between children, adolescents, and adults with asthma and allergic rhinitis
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Lee NG, Kim HK, Choi GS
- KMID: 2519025
- Allergy Asthma Respir Dis.
- 2021 Jul;9(3):148-155.
- doi: 10.4168/aard.2021.9.3.148
Purpose: Inhalant allergens are known as a major factor for respiratory allergic diseases. There are many differences in sensitization rates of inhalant allergens, depending on the environment and demographic factors.... -
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- Cluster Analysis of Inhalant Allergens in South Korea: A Computational Model of Allergic Sensitization
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Kim DK, Park YS, Cha KJ, Jang D, Ryu S, Kim KR, Kim SH, Yoon HJ, Cho SH
- KMID: 2512887
- Clin Exp Otorhinolaryngol.
- 2021 Feb;14(1):93-99.
- doi: 10.21053/ceo.2019.01921
Objectives. Sensitization to specific inhalant allergens is a major risk factor for the development of atopic diseases, which impose a major socioeconomic burden and significantly diminish quality of life. However,... -
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- Safety and Utility of Rush Immunotherapy with Aqueous Allergen Extracts for Treatment of Respiratory Allergies
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Lee JH, Choi JH, Jeong KB, Lee SJ, Lee MK, Lee WY, Yong SJ, Kim SH
- KMID: 2510738
- J Korean Med Sci.
- 2021 Jan;36(3):e18.
- doi: 10.3346/jkms.2021.36.e18
Background: Generally, allergen immunotherapy must be administered for three to five years. Meanwhile, rush immunotherapy (RIT) shortens the required duration for the build-up phase, thereby improving the therapy's convenience compared... -
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- Comparison of Allergenic Properties among Commercially Available House Dust Mite Allergen Extracts in Korea
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Kim JT, Kim H, Kim SH, Kim DJ, Shin Y, Kim JD, Song H, Jang SW, Lee Dc, Park KH, Lee JH, Jeong KY, Park JW
- KMID: 2509864
- Yonsei Med J.
- 2021 Jan;62(1):86-90.
- doi: 10.3349/ymj.2021.62.1.86
Precise allergy diagnosis and effective allergen specific immunotherapy are largely dependent on the quality of allergen extract. A new extract of Dermatophagoides farinae was commercially developed by Prolagen. The allergenic... -
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- Revision of threshold levels for evoking pollinosis to oak, pine, Japanese hop, and ragweed in the metropolitan area Seoul, Korea
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Choi YJ, Jeon JH, Jeong JH, Kim KR, Lee YS, Oh JW
- KMID: 2508225
- Allergy Asthma Respir Dis.
- 2020 Oct;8(4):199-205.
- doi: 10.4168/aard.2020.8.4.199
Purpose: The threshold levels for symptom development of pollinosis vary among studies and countries. This study aimed to determine currently used threshold levels for it. Methods: Oak, pine, Japanese hop, and... -
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- Basophil Activation Test Based on CD203c Expression in the Diagnosis of Fish Allergy
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Imakiire R, Fujisawa T, Nagao M, Tokuda R, Hattori T, Kainuma K, Kawano Y
- KMID: 2500744
- Allergy Asthma Immunol Res.
- 2020 Jul;12(4):641-652.
- doi: 10.4168/aair.2020.12.4.641
Purpose: The basophil activation test (BAT) has been reported to be useful for the diagnosis of various food allergies, such as allergy to peanut, but not to fish. This study... -
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- Inhibition of Cross-Reactive Carbohydrate Determinant–Specific IgEs Reduce False Positive Reponses to Multiple Allergen Simultaneous Test–Immunoblot Assay: A Case Study
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Song DY, Lee JH, Kim SM, Jun SH, Lee K, Song SH, Song J
- KMID: 2504135
- Lab Med Online.
- 2020 Jul;10(3):242-246.
- doi: 10.3343/lmo.2020.10.3.242
Cross-reactive carbohydrate determinants (CCDs) are simple carbohydrates linked to amino acid chains; they are found in pollens, vegetable foods, insect, and Hymenoptera venoms and are broadly cross-reactive with CCD-specific IgE... -
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- Validation of a Multiplex Assay for Measuring Specific IgG4
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Kim SR, Park KH, Lee JE, Kim BJ, Lim KJ, Park JW
- KMID: 2502233
- Yonsei Med J.
- 2020 Jun;61(6):524-532.
- doi: 10.3349/ymj.2020.61.6.524
Purpose: Specific IgG4 (sIgG4) increases with allergen specific immunotherapy and may reflect a state of immune tolerance in food allergy. While ImmunoCAP® has been widely used to measure sIgG4 to... -
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- Atopic Patients Who Fulfilled Rome III Criteria for Irritable Bowel Syndrome Had Higher Animal Danders Sensitization
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Siah KTH, Santosa A, Cheung CKY, Soh AYS, Bigliardi
- KMID: 2500684
- J Neurogastroenterol Motil.
- 2020 Apr;26(2):267-273.
- doi: 10.5056/jnm19181
Background/Aims The relationship between animal exposure and irritable bowel syndrome (IBS) is debated. Epidemiological studies have shown that atopy is more prevalent in IBS patients and vice versa. We set... -
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- Intralymphatic allergen-specific immunotherapy
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Kang SY, Jung JH, Lee SM, Lee SP
- KMID: 2500179
- Allergy Asthma Respir Dis.
- 2020 Apr;8(2):53-65.
- doi: 10.4168/aard.2020.8.2.53
Although allergen-specific immunotherapy (AIT) is a standard treatment for allergic diseases, only 5% or less of patients in whom AIT is indicated have been receiving immunotherapy because AIT needs a... -
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- Primary Nasal Epithelial Cells From Allergic and Non-allergic Individuals Show Comparable Barrier Function
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Waltl EE, Stanek V, Mueller CA, Kiss R, Eckl-Dorna J, Valenta R, Niederberger V
- KMID: 2468468
- Allergy Asthma Immunol Res.
- 2020 Mar;12(2):364-370.
- doi: 10.4168/aair.2020.12.2.364
Previous reports suggested that ex vivo cultured primary nasal epithelial cells from allergic patients differ from those from non-allergic individuals by genuinely reduced barrier function. By contrast, we found that... -
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