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Lipopolysaccharide-induced Autophagy Increases SOX2-positive Astrocytes While Decreasing Neuronal Differentiation in the Adult Hippocampus

Liu WC, Wu CW, Fu MH, Tain YL, Liang CK, Chen IC, Hung CY, Lee YC, Wu KL

  • KMID: 2535062
  • Exp Neurobiol.
  • 2022 Oct;31(5):307-323.
  • doi: 10.5607/en22005
Inflammation alters the neural stem cell (NSC) lineage from neuronal to astrogliogenesis. However, the underlying mechanism is elusive. Autophagy contributes to the decline in adult hippocampal neurogenesis under E. coli...
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Normal Adult Hippocampal Neurogenesis in SRG3-overexpressing Transgenic Mice

Kim B, Lee E, Seong RH, Chung H, Son H

SRG3 (SWI3-related gene) is a core subunit of mouse SWI/SNF complex and is known to play a critical role in stabilizing the SWI/SNF complex by attenuating its proteasomal degradation. SWI/SNF...
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