- Current Molecular Imaging Positron Emitting Radiotracers in Oncology
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Zhu A, Shim H
- KMID: 2051988
- Nucl Med Mol Imaging.
- 2011 Mar;45(1):1-14.
Molecular imaging is one of the fastest growing areas of medical imaging. Positron emission tomography (PET) has been widely used in the clinical management of patients with cancer. Nuclear imaging... -
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- Structural Requirements for Modulating 4-Benzylpiperidine Carboxamides from Serotonin/Norepinephrine Reuptake Inhibitors to Triple Reuptake Inhibitors
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Paudel S, Kim E, Zhu A, Acharya S, Min X, Cheon SH, Kim KM
- KMID: 2517157
- Biomol Ther.
- 2021 Jul;29(4):392-398.
- doi: 10.4062/biomolther.2020.233
In this study, we determined the effect of 24 different synthetic 4-benzylpiperidine carboxamides on the reuptake of serotonin, norepinephrine, and dopamine (DA), and characterized their structure–activity relationship. The compounds with... -
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- Structure–Activity Relationship and Evaluation of Phenethylamine and Tryptamine Derivatives for Affinity towards 5-Hydroxytryptamine Type 2A Receptor
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Wang S, Zhu A, Paudel S, Jang CG, Lee YS, Kim KM
- KMID: 2539586
- Biomol Ther.
- 2023 Mar;31(2):176-182.
- doi: 10.4062/biomolther.2022.096
Among 14 subtypes of serotonin receptors (5-HTRs), 5-HT 2AR plays important roles in drug addiction and various psychiatric disorders. Agonists for 5-HT 2AR have been classified into three structural groups:... -
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- Potential Functional Role of Phenethylamine Derivatives in Inhibiting Dopamine Reuptake: Structure–Activity Relationship
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Kundu D, Zhu A, Kim E, Paudel S, Jang CG, Lee YS, Kim KM
- KMID: 2537587
- Biomol Ther.
- 2023 Jan;31(1):108-115.
- doi: 10.4062/biomolther.2022.047
Numerous psychotropic and addictive substances possess structural features similar to those of β-phenethylamine (β-PEA). In this study, we selected 29 β-PEA derivatives and determined their structure–activity relationship (SAR) to their... -
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- Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression
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Liang Z, Cho HT, Williams L, Zhu A, Liang K, Huang K, Wu H, Jiang C, Hong S, Crowe R, Goodman MM, Shim H
- KMID: 2313132
- Nucl Med Mol Imaging.
- 2011 Jun;45(2):93-102.
PURPOSE: L-type amino acid transporter 1 (LAT1) is essential for the transport of large neutral amino acids. However, its role in breast cancer growth remains largely unknown. The purpose of... -
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