- Gene Therapy of Brain Tumors:Effects of Adenovirus-mediated Wild Type p53 Gene Transfer in Human Glioma Cells
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Hong YK, Yung WK
- KMID: 2018899
- J Korean Neurosurg Soc.
- 1996 Aug;25(8):1561-1567.
The p53 tumor suppressor gene is one of the genes with greatest therapeutic potential for cancer treatment and its growth inhibitory mechanism is thought to be mediated through the activation... -
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- Potentials and limitations of adenovirus-p53 gene therapy for brain tumors
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Hong YK, Joe YA, Yang YJ, Lee KS, Son BC, Jeun SS, Chung DS, Cho KK, Park CK, Kim MC, Kim HK, Yung WK, Kang JK
- KMID: 1128631
- J Korean Med Sci.
- 2000 Jun;15(3):315-322.
- doi: 10.3346/jkms.2000.15.3.315
We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and... -
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