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The Comparison of Emergency Medical Service Responses to and Outcomes of Out-of-hospital Cardiac Arrest before and during the COVID-19 Pandemic in an Area of Korea

Lim D, Park SY, Choi B, Kim SH, Ryu JH, Kim YH, Sung AJ, Bae BK, Kim HB

Background: Since the declaration of the coronavirus disease 2019 (COVID-19) pandemic, COVID-19 has affected the responses of emergency medical service (EMS) systems to cases of out-of-hospital cardiac arrest (OHCA). The...
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Gastroprotective effect of cirsilineol against hydrochloric acid/ ethanol-induced gastric ulcer in rats

Gong G,  Zhao R, Zhu Y, Yu J, Wei B, Xu Y, Cui Z, Liang G

This study was designed to evaluate the gastroprotective activity of cirsilineol in hydrochloric acid (HCl)/ethanol-induced gastric ulcer model. Cirsilineol was administered at the doses of 20 and 40 mg/kg in HCl/ethanol-induced...
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Treatment Patterns of Type 2 Diabetes Assessed Using a Common Data Model Based on Electronic Health Records of 2000–2019

Lee KA, Jin HY, Kim YJ, Im YJ, Kim EY, Park TS

Background: Real-world data analysis is useful for identifying treatment patterns. Understanding drug prescription patterns of type 2 diabetes mellitus may facilitate diabetes management. We aimed to analyze treatment patterns of type...
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Biomechanical Analysis of the Kirschner-Wire Depth of the Modified Tension Band Wiring Technique in Transverse Patellar Fractures: An Experimental Study Using the Finite-Element Method

Kim Y, Kwon M, Ryu JY, Moon SW

Background: Modified tension band wiring is one of the most preferred surgical methods for transverse patellar fractures. However, the optimal depth or sagittal position of a Kirschner wire (K-wire) in...
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Platelet-Derived Growth Factor Receptor-α Subunit Targeting Suppresses Metastasis in Advanced Thyroid Cancer In Vitro and In Vivo

Lin CL, Tsai ML, Chen Yh, Liu WN, Lin CY, Hsu KW, Huang CY, Chang YJ, Wei PL, Chen SH, Huang LC, Lee CH

Thyroid cancer is the most common endocrine malignancy. Patients with well-differentiated thyroid cancers, such as papillary and follicular cancers, have a favorable prognosis. However, poorly differentiated thyroid cancers, such as...
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Clinical Practice Guideline for Frailty Applicable in Primary Care Setting

You HS, Kwon YJ, Kim S, Kim YH, Kim Ys, Kim Y, Roh Yk, Park B, Park YK, Park CH, Son JS, Shin J, Shin HY, Oh B, Lee Jw, Shim JY, Won CW, Yoo JW, Lee SH, Kang HT, Lee DC

With aging becoming a global issue, the interest in healthy aging has increased as well. Healthy aging focuses on maintaining the functions and wellbeing of the elderly rather than merely...
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Management of prosthodontic patients with severe gag reflex using the questionaire and behavior technique: A case report

Sohn C, Kim YJ, Lee CS, Choi NR, Kwon EY, Kim SY

Although gag reflex is an essential function and a useful physiological defense mechanism, it can become an obstacle in a dental treatment. In this case, a questionnaire was designed and...
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Questionnaire-based Survey of Demographic and Clinical Characteristics, Health Behaviors, and Mental Health of Young Korean Adults with Early-onset Diabetes

Park JI, Baek H, Kim SW, Jeong JY, Song KH, Yu JH, Nam-Goong IS, Cho EH

Background: The incidence of early-onset diabetes is increasing among young adults. However, there are limited data on the characteristics and management of young Korean adults with diabetes. This study assessed the...
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Variations for Incomplete Formation of the Plantaris Muscle: A Case Report

Park KR, Cho J, Choi YJ, Lee M, Kim D, Kwon HW, Park J

We present a case of variation of origin and tendon disappearance in a 58-year-old Korean male cadaveric specimen in our routine dissections. First, the origin of the plantaris muscle is...
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Nanoparticles: Weighing the Pros and Cons from an Eco-genotoxicological Perspective

Koedrith P, Rahman M, Jang YJ, Shin DY, Seo YR

The exponential growth of nanotechnology and the industrial production have raised concerns over its impact on human and environmental health and safety (EHS). Although there has been substantial progress in...
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Status of caries in permanent teeth of the adolescent in Ansan city after the suspension of the community water fluoridation program

Ryu JI, Jung SH, Lee SR, Lim AR

Objectives: Community Water Fluoridation (CWF) was suspended in Ansan city in 2018. The purpose of this study was to inspect the status of caries in the permanent teeth of adolescents...
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A qualitative study on the evaluation of the registered dentists’ program of dentists

Ryu JI, Park HA, Lee SJ, Jeon JE

Objectives: This study aimed to evaluate the registered dentists’ program, from the dentist’s perspective, before its nationwide implementation. Methods: In-depth interviews were conducted with 18 dentists who had participated in the...
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Association between Depression and hs-CRP Blood Levels in Korean Adults: Using the National Health and Nutrition Survey 2018

Ahn MH, Eom YJ, Park YK

Background: In previous studies, C-reactive protein (CRP), interleukin (IL)-6, and IL-1 increased in depressed patients. Experimental and clinical evidence has reported that inflammatory mediators can induce symptoms of depression. Therefore,...
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Vascularized Organoids: A More Complete Model

Yu J

As an emerging research model in vitro, organoids have achieved major progress in recapitulating morphological aspects of organs and personalized precision therapy. Various organoids have been currently constructed in vitro...
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Predictive Role of Lung Injury Prediction Score in the Development of Acute Respiratory Distress Syndrome in Korea

Kim BK, Kim S, Kim CY, Kim YJ, Lee SH, Cha JH, Kim JH

Purpose: Early recognition and therapeutic intervention are important in patients at high risk of acute respiratory distress syndrome (ARDS). The lung injury prediction score (LIPS) has been used to predict...
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Organoids: A New Model for SARS-CoV-2 Translational Research

Yu J

The 2019-novel coronavirus (SARS-CoV-2) pneumonia epidemic is a thorny public health problem faced by health officials and a major cause of concern for health professionals. However, the currently used immortalized...
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Comparison of Clinical Outcomes of Borderline Resectable Pancreatic Cancer According to the Neoadjuvant Chemo-Regimens: Gemcitabine versus FOLFIRINOX

Choi YJ, Byun Y, Kang JS, Kim HS, Han Y, Kim H, Kwon W, Oh DY, Paik WH, Lee SH, Ryu JK, Kim YT, Lee K, Kim H, Chie EK, Jang JY

Background/Aims: Although many studies have reported the promising effect of neoadjuvant treatment for borderline resectable pancreatic cancer (BRPC) to increase resectability, only a few studies have recommended the use of...
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Incidence of adverse drug reaction among 6 iodinated contrast media

Koh E, Kim YJ, Kang N, Jin SR, Lee JY, Eo H, Choi DC, Lee BJ

Purpose: Contrast media is one of the most common cause of adverse drug reaction (ADR) in adult. However, there was little data reported about differences in ADR ratio and severity...
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Lifestyle, Health Status and Socioeconomic Factors Associated with Depressive Symptoms in Korean Young Adults: Korean National Health and Nutrition Examination Survey 2017

Chung YJ, Jung HH, Jung C, Lim HS, Kim SC

Background: In recent years, the number of suicides in young adults has increased rapidly, leading to a major social problem. According to several reports, suicide is closely related to depressive...
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Impact of the COVID-19 Outbreak on Emergency Care Utilization in Patients with Acute Myocardial Infarction: a Nationwide Population-based Study

Sung HK, Paik JH, Lee YJ, Kang S

Background: The coronavirus disease 2019 (COVID-19) pandemic has impacted various aspects of daily living and has influenced the life of every individual in a unique way. Acute myocardial infarction (AMI) is...
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