- Identification of molecular markers for the oncogenic differentiation of hepatocellular carcinoma
-
Yu GR, Kim SH, Park SH, Cui XD, Xu DY, Yu HC, Cho BH, Yeom YI, Kim SS, Kim SB, Chu IS, Kim DG
- KMID: 1090967
- Exp Mol Med.
- 2007 Oct;39(5):641-652.
The aim of this study was to identify molecular markers associated with oncogenic differentiation in hepatocellular carcinoma (HCC). Using an unsupervised clustering method with a cDNA microarray, HCC (T) gene... -
- CITED
-
- Close
- SHARE
-
- Close
- Genetic and expression alterations in association with the sarcomatous change of cholangiocarcinoma cells
-
Yoo HJ, Yun BR, Kwon JH, Ahn HS, Seol MA, Lee MJ, Yu GR, Yu HC, Hong B, Choi K, Kim DG
- KMID: 1109433
- Exp Mol Med.
- 2009 Feb;41(2):102-115.
- doi: 10.3858/emm.2009.41.2.013
Cholangiocarcinoma (CC) is an intrahepatic bile duct carcinoma with a high mortality rate and a poor prognosis. Sarcomatous change/epithelial mesenchymal transition (EMT) of CC frequently leads to aggressive intrahepatic spread... -
- CITED
-
- Close
- SHARE
-
- Close
- C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling
-
Lee S, Lee MJ, Zhang J, Yu GR, Kim DG
- KMID: 2367551
- Exp Mol Med.
- 2016 Dec;48(12):e275.
- doi: 10.1038/emm.2016.107
C-terminal-truncated hepatitis B virus (HBV) X (HBx) (ctHBX) is frequently detected in hepatocellular carcinoma (HCC) through HBV integration into the host genome. However, the molecular mechanisms underlying ctHBx-associated oncogenic signaling... -
- CITED
-
- Close
- SHARE
-
- Close
- Enhancement of parthenolide-induced apoptosis by a PKC-alpha inhibition through heme oxygenase-1 blockage in cholangiocarcinoma cells
-
Yun BR, Lee MJ, Kim JH, Kim IH, Yu GR, Kim DG
- KMID: 994402
- Exp Mol Med.
- 2010 Nov;42(11):787-797.
- doi: 10.3858/emm.2010.42.11.082
Cholangiocarcinoma (CC) is a chemoresistant intrahepatic bile duct carcinoma with a poor prognosis. The aims of this study were to identify molecular pathways that enhance sesquiterpene lactone parthenolide (PTL)-induced anticancer... -
- CITED
-
- Close
- SHARE
-
- Close
- Pro-oncogenic potential of NM23-H2 in hepatocellular carcinoma
-
Lee MJ, Xu DY, Li H, Yu GR, Leem SH, Chu IS, Kim IH, Kim DG
- KMID: 1245264
- Exp Mol Med.
- 2012 Mar;44(3):214-224.
- doi: 10.3858/emm.2012.44.3.016
NM23 is a family of structurally and functionally conserved proteins known as nucleoside diphosphate kinases (NDPK). There is abundant mRNA expression of NM23-H1, NM23-H2, or a read through transcript (NM23-LV)... -
- CITED
-
- Close
- SHARE
-
- Close
