- The upstream sequence of Mycobacterium leprae 18-kDa gene confers transcription repression activity in orientation-independent manner
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Kim HB, You JC
- KMID: 1103317
- Exp Mol Med.
- 2004 Dec;36(6):510-514.
In order to understand the role of the upstream region of the Mycobacterium leprae 18-kDa gene on the gene regulation, the region was divided into two at the -50 position... -
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- Heterologous Regulation of BCG hsp65 Promoter by M. leprae 18 kDa Transcription Repression Responsive Element
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Kim HB, You JC
- KMID: 2053075
- Genomics Inform.
- 2003 Dec;1(2):113-118.
Among a number of antigens characterized in M. leprae, an etiological agent of Leprosy, the 18 kDa antigen, is unique to M. leprae. We have previously determined a sequence specific... -
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- Pseudotype HIV-1 Particles Carrying CD4
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Park SW, Kim TG, You JC, Schubert M, Paik SY
- KMID: 1896565
- J Korean Soc Virol.
- 2000 Mar;30(1):83-99.
A defective HIV-1 helper virus DNA, pHyPC, was assembled by deleting the RNA packaging signal, env, nef and the 3'LTR sequences. HIV-1 like virus particles that carry the HIV-1 receptor,... -
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- Down-regulation of ATP-binding cassette transporter G1 expression by unmethylated CpG oligodeoxynucleotides in RAW 264.7 macrophages
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Seo JM, Lee JY, Ji GE, You JC
- KMID: 1022127
- Exp Mol Med.
- 2011 Sep;43(9):510-516.
- doi: 10.3858/emm.2011.43.9.058
We have investigated the effect of various forms of phosphodiester cytidine-phosphate-guanosine oligodeoxynucleotides (CpG ODNs) on the production of pro-inflammatory cytokines and related genes in RAW 264.7 macrophages. Treatment with the... -
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- The Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein, a toll-like receptor 4 agonist, enhances dendritic cell-based cancer vaccine potency
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Noh KT, Shin SJ, Son KH, Jung ID, Kang HK, Lee SJ, Lee EK, Shin YK, You JC, Park YM
- KMID: 1383795
- Exp Mol Med.
- 2012 May;44(5):340-349.
In this study, we showed the direct interaction between Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein (FAP) and toll-like receptor4 (TLR4) via co-localization and binding by using confocal microscopy and... -
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