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Construction of EST Database for Comparative Gene Studies of Acanthamoeba

Moon EK, Kim JO, Xuan YH, Yun YS, Kang SW, Lee YS, Ahn TI, Hong YC, Chung DI, Kong HH

The genus Acanthamoeba can cause severe infections such as granulomatous amebic encephalitis and amebic keratitis in humans. However, little genomic information of Acanthamoeba has been reported. Here, we constructed Acanthamoeba...
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Keratitis by Acanthamoeba triangularis: Report of Cases and Characterization of Isolates

Xuan YH, Chung BS, Hong YC, Kong HH, Hahn TW, Chung DI

Three Acanthamoeba isolates (KA/E9, KA/E17, and KA/E23) from patients with keratitis were identified as Acanthamoeba triangularis by analysis of their molecular characteristics, a species not previously recognized to be a...
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The Expression of G1-S Cell Cycle Inhibitors in Normal Placenta and Gestational Trophoblastic Diseases

Xuan YH, Kim KH, Choi YL, Ahn GH, Chae SW, Lee HC, Lee OJ, Kim SH

  • KMID: 1163252
  • Korean J Pathol.
  • 2008 Apr;42(2):67-74.
BACKGROUND: The objective of this study is to determine the expression pattern of G1-S inhibitor molecules in normal trophoblasts and gestational trophoblastic diseases, including hydatidiform moles and choriocarcinoma. METHODS:...
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Molecular characterization of bacterial endosymbionts of Acanthamoeba isolates from infected corneas of Korean patients

Xuan YH, Yu HS, Jeong HJ, Seol SY, Chung DI, Kong HH

The endosymbionts of 4 strains of Acanthamoeba (KA/E9, KA/E21, KA/E22, and KA/E23) isolated from the infected corneas of Korean patients were characterized via orcein stain, transmission electron microscopic examination, and...
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Microarray Analysis of Differentially Expressed Genes between Cysts and Trophozoites of Acanthamoeba castellanii

Moon EK, Xuan YH, Chung DI, Hong Y, Kong HH

Acanthamoeba infection is difficult to treat because of the resistance property of Acanthamoeba cyst against the host immune system, diverse antibiotics, and therapeutic agents. To identify encystation mediating factors of...
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Molecular characterization of Acanthamoeba isolated from amebic keratitis related to orthokeratology lens overnight wear

Lee SJ, Jeong HJ, Lee JE, Lee JS, Xuan YH, Kong HH, Chung DI, Ock MS, Yu HS

In an effort to characterize, on the molecular scale, the Acanthamoeba initially isolated from the cornea of an amoebic keratitis patient associated with overnight-wear orthokeratology lens in Korea, we conducted...
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Endosymbionts of Acanthamoeba Isolated from Domestic Tap Water in Korea

Choi SH, Cho MK, Ahn SC, Lee JE, Lee JS, Kim DH, Xuan YH, Hong YC, Kong HH, Chung DI, Yu HS

In a previous study, we reported our discovery of Acanthamoeba contamination in domestic tap water; in that study, we determined that some Acanthamoeba strains harbor endosymbiotic bacteria, via our molecular...
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