- Cyclooxygenase-2 Inhibitor Parecoxib Was Disclosed as a PPAR-γ Agonist by In Silico and In Vitro Assay
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Xiao B, Li Dd, Wang Y, Kim EL, Zhao N, Jin SW, Bai DH, Sun LD, Jung JH
- KMID: 2519617
- Biomol Ther.
- 2021 Sep;29(5):519-526.
- doi: 10.4062/biomolther.2021.008
In a search for effective PPAR-γ agonists, 110 clinical drugs were screened via molecular docking, and 9 drugs, including parecoxib, were selected for subsequent biological evaluation. Molecular docking of parecoxib... -
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- Effects of resveratrol on the inflammatory response and renal injury in hyperuricemic rats
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Xiao B, Ma W, Zheng Y, Li Z, Li D, Zhang Y, Li Y, Wang D
- KMID: 2511671
- Nutr Res Pract.
- 2021 Feb;15(1):26-37.
- doi: 10.4162/nrp.2021.15.1.26
BACKGROUND/OBJECTIVES: Hyperuricemic nephropathy is a common cause of acute kidney injury. Resveratrol can ameliorate kidney injury, but the explicit mechanism remains unclear. We investigated the effects of resveratrol on the inflammatory... -
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- A Novel Polyclonal Antiserum against Toxoplasma gondii Sodium Hydrogen Exchanger 1
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Xiao B, Kuang Z, Zhan Y, Chen D, Gao Y, Li M, Luo S, Hao W
- KMID: 2374013
- Korean J Parasitol.
- 2016 Feb;54(1):21-29.
- doi: 10.3347/kjp.2016.54.1.21
The sodium hydrogen exchanger 1 (NHE1), which functions in maintaining the ratio of Na+ and H+ ions, is widely distributed in cell plasma membranes. It plays a prominent role in... -
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