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Dietary Glutamate: Interactions With the Enteric Nervous System

Wang GD, Wang XY, Xia Y, Wood JD

  • KMID: 2381148
  • J Neurogastroenterol Motil.
  • 2014 Jan;20(1):41-53.
BACKGROUND/AIMS: Digestion of dietary protein elevates intraluminal concentrations of glutamate in the small intestine, some of which gain access to the enteric nervous system (ENS). Glutamate, in the central nervous...
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Anti-Enteric Neuronal Antibodies and the Irritable Bowel Syndrome

Wood JD, Liu S, Drossman D, Ringel Y, Whitehead

  • KMID: 2325863
  • J Neurogastroenterol Motil.
  • 2012 Jan;18(1):78-85.
BACKGROUND/AIMS: Functional gastrointestinal disorders are those in which no abnormal metabolic or physical processes, which can account for the symptoms, can be identified. The irritable bowel syndrome (IBS) is a...
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Changes in Enteric Neurons of Small Intestine in a Rat Model of Irritable Bowel Syndrome with Diarrhea

Li S, Fei G, Fang X, Yang X, Sun X, Qian J, Wood JD, Ke M

  • KMID: 2203585
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):310-320.
  • doi: 10.5056/jnm15082
BACKGROUND/AIMS: Physical and/or emotional stresses are important factors in the exacerbation of symptoms in irritable bowel syndrome (IBS). Several lines of evidence support that a major impact of stress on...
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