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Expression of Fibronectin, Vitronectin, Surfactant-A and D in Interaction of Pneumocystis carinii and Alveolar Epithelial Cells in Pneumocystis carinii Pneumonia

Kwon KY, Jeon YJ, Chang ES

  • KMID: 1725722
  • Korean J Pathol.
  • 2000 Sep;34(9):625-635.
Both fibronectin and vitronectin bind to Pneumocystis carinii (P. carinii) and mediate the attachment of the organisms to respiratory epithelial cells. Surfactant A and D play a role in the...
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Apoptosis of Alveolar Cells in Pneumocystis Carinii Pneumonia: Application of Electron Microscopic Terminal Deoxynucleotidyl Transferase-Mediated dUTP-Biotin Nick End Labeling Method

Kang KH, Kim SP, Kwon KY

  • KMID: 2275589
  • Korean J Pathol.
  • 2001 Dec;35(6):496-505.
BACKGROUND: Pneumocystis carinii (P. carinii) attaches to alveolar cells and causes injury to the epithelial cells by direct toxic effects or inhibition of epithelial growth and replication. Although respiratory cell...
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Inhibition of Corneal Angiogenesis by Antibody to Integrin b3 Subunit

Chung SK, Lee JY, Hwang DG

  • KMID: 2123752
  • J Korean Ophthalmol Soc.
  • 1997 Jan;38(1):1-6.
Vascular endothelial cell expression of avb3, and integrin receptor that binds von Willebrand factor, vitronectin, and fibrinogen, increases in response to angiogenic stimuli such as basic fibroblast growth factor(bFGF) and...
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Inhibitory Effect of Antibody to alphavbeta5 in Corneal Angiogenesis

Kim KS, Yang JW, Chung SK, Baek NH

  • KMID: 2124942
  • J Korean Ophthalmol Soc.
  • 2001 Nov;42(11):1594-1599.
PURPOSE: This study investigated the importance of alphavbeta5 function during vascular endothelial growth factor (VEGF) induced corneal angiogenesis by examining the effects of antibody to alphavbeta5 that blocks alphav 5-mediated...
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Reactive Oxygen Species Production, Expression of Complement Regulator Genes and Phagocytosis in the Murine Microglial Cell after Administration of Beta-Amyloid(A beta1-42) Protein

Choi YS, Lee KS, Kim SH

  • KMID: 1626985
  • J Korean Neurol Assoc.
  • 2005 Feb;23(1):88-95.
BACKGROUND: Microglia is a primary cellular component of neuritic plaques in Alzheimer's disease. Beta amyloid deposits attract microglia and activate them to produce inflammatory mediators. The objectives of this study...
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Inhibition of Vascular Endothelial Growth Factor Induced Corneal Angiogenesis by Antibody to Intergrin beta3 Subunit

Lee JY, Chung SK, Hwang DG

  • KMID: 2147738
  • J Korean Ophthalmol Soc.
  • 1997 May;38(5):744-749.
Vascular cells respond to multiple cytokines, they also express a variety of integrin adhesion receptor. A number of the vascular cell integrins are functionally and structurally homologous, suggesting some level...
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Expression Change of Complement Regulator Genes of the Human Astrocytoma Cell Line after A beta1-42 and Interferon Gamma Administration

Choi YS, Kim SH

  • KMID: 2338935
  • J Korean Geriatr Soc.
  • 2008 Dec;12(4):235-245.
BACKGROUND: We determined the changes of complement regulator gene expression in the amyloid-beta1-42(A beta1-42) and interferon-gamma(IFN-gamma)-stimulated human astrocytoma cell line. METHODS: The human astrocytoma cell line, U373MG, was stimulated with IFN-gamma(62.5-1,000U/ml)...
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Analysis of Platelet Membrane Glycoprotein Iib-IIIa Complex in Whole Blood of Glanzmann's Thrombasthenia by Flow Cytometry

Lee BG, Kang MC, Park JM, Hwang PH, Kim JS

  • KMID: 2208413
  • J Korean Pediatr Soc.
  • 1994 Nov;37(11):1540-1547.
Glanzmann's thrombasthenia is a rare autosomal recessive hemorrhagic disorder characterized by prolonged bleeding time, ad deficient or absent clot retraction in the presence of normal platelet count. The major underlying...
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Inhibition of Transfer Infection of Epstein-Barr Virus to Epithelial Cells by Integrin beta6 siRNA

Kim SY, Lee SK

Epstein-Barr virus (EBV) establishes a latent infection in greater than 90% of the world's adult population and associates with various tumors. EBV primarily infects epithelial cells and B cell in...
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Interleukin-33 and Mast Cells Bridge Innate and Adaptive Immunity: From the Allergologist's Perspective

Jang TY, Kim YH

Interleukin (IL) 33, a member of the IL-1 superfamily, is an "alarmin" protein and is secreted in its active form from damaged cells undergoing necrotic cell death. Mast cells are...
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Lipid Raft Integrity Is Required for Survival of Triple Negative Breast Cancer Cells

Badana A, Chintala M, Varikuti G, Pudi N, Kumari S, Kappala VR, Malla RR

PURPOSE: Lipid rafts are cholesterol enriched microdomains that colocalize signaling pathways involved in cell proliferation, metastasis, and angiogenesis. We examined the effect of methyl-β-cyclodextrin (MβCD)-mediated cholesterol extraction on the proliferation,...
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Novel Associations between Related Proteins and Cellular Effects of High-Density Lipoprotein

Choi S, Park YE, Cheon EJ, Kim KY, Kim M, Ann SJ, Noh HM, Lee J, Lee CJ, Lee ST, Lee C, Lee JE, Lee SH

BACKGROUND AND OBJECTIVES: Recent studies have examined the structure-function relationship of high-density lipoprotein (HDL). This study aimed to identify and rank HDL-associated proteins involved in several biological function of HDL. METHODS:...
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betaig-h3 triggers signaling pathways mediating adhesion and migration of vascular smooth muscle cells through alphavbeta5 integrin

Lee BH, Bae JS, Park RW, Kim JE, Park JY, Kim IS

  • KMID: 1111408
  • Exp Mol Med.
  • 2006 Apr;38(2):153-161.
Adhesion and migration of vascular smooth muscle cells (VSMCs) play an important role in the pathogenesis of atherosclerosis. These processes involve the interaction of VSMCs with extracellular matrix proteins. Here,...
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