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Organoid as a culture system for viral vaccine strains

Hong KJ, Seo SH

Organoid is an in vitro multicellular form mimicking in vivo organ. Its similarity to human organ including cellular organization, molecular expression patterns, as well as genetic signatures enables to study...
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Comparison of R-mix Virus Culture and Multiplex Reverse Transcriptase-PCR for the Rapid Detection of Respiratory Viruses

Lim G, Park TS, Suh JT, Lee HJ

BACKGROUND: Respiratory viral infections can become epidemic due to high contagiosity. Since there was no rapid diagnostic method for complete diagnosis in the past, diagnosis was solely made on the...
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Recurrent Herpes-Stomatitis Mimicking Acute Necrotizing Ulcerative Gingivitis

Kim HS, Lee SK, Park YW

  • KMID: 2136924
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2011 Jan;33(1):89-92.
Herpes simplex is caused by viruses of the herpesvirus hominus family. HSV have four categories: type 1, 2, 6, and 8. Generally HSV-1 affects the mouth. Once infected by HSV,...
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Development of a packaging cell line for propagation of replication-deficient adenovirus vector

Kim JS, Lee SH, Cho YS, Park KS, Kim YH, Lee JH

  • KMID: 938878
  • Exp Mol Med.
  • 2001 Sep;33(3):145-149.
A human embryonic kidney cell line 293 is widely used for adenovirus production and propagation. With this cell line, however, replication-competent virus (RCV) is frequently generated, especially during large-scale production...
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