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Expression of hepatitis C virus nonstructural 4B in transgenic mice

Wang AG, Moon HB, Kim JM, Hwang SB, Yu DY, Lee DS

  • KMID: 1094149
  • Exp Mol Med.
  • 2006 Jun;38(3):241-246.
Hepatitis C virus (HCV) is a pathogen that is of great medical significance in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma worldwide. Although the HCV proteins have been intensively investigated...
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Immunogenicity of baculovirus expressed recombinant proteins of Japanese encephalitis virus in mice

Yang DK, Kweon CH, Kim BH, Lim SI, Kwon JH, Kim SH, Song JY, Han HR

  • KMID: 1114853
  • J Vet Sci.
  • 2005 Jun;6(2):125-133.
Genes encoding for the premembrane and envelope (prME), envelope (E) and nonstructural protein (NS1) of Japanese encephalitis virus (JEV) were cloned. Each protein was expressed in baculovirus expression system. Of...
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The prediction of interferon-alpha therapeutic effect by sequence variation of the HCV hypervariable region 1

Yeh BI, Kim HW, Kim HS, Lee JY, Lee KH, Lee KM, Kim JS, Han KH

Interferon-alpha (IFN-alpha) has been used to treat hepatitis C virus (HCV)-induced hepatitis, but it has been effective in only about half of the treated patients, with recurrence appearing in the...
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