- Clinical Effects of Calcium Channel Blocker and Angiotensin Converting Enzyme Inhibitor on Endothelial Function and Arterial Stiffness in Patients with Angina Pectoris
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Kim KH, Jeong MH, Cho SH, Moon JY, Hong YJ, Park HW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC
- KMID: 1779122
- J Korean Med Sci.
- 2009 Apr;24(2):223-231.
- doi: 10.3346/jkms.2009.24.2.223
To evaluate the effects of calcium channel blocker (CCB) and angiotensin converting enzyme inhibitor (ACEI) on endothelial function and arterial stiffness in stable angina pectoris (SAP), 87 patients with SAP... -
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- Activation of Ca(2+)-activated K+ channels by beta agonist in rabbit coronary smooth muscle cells
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Ahn DS, Jeong YK, Lee YH, Kang BS
- KMID: 1123178
- Yonsei Med J.
- 1995 Jun;36(3):232-242.
- doi: 10.3349/ymj.1995.36.3.232
Isoproterenol (ISO), a beta agonist, causes hyperpolarization of coronary smooth muscle cells via an increase in K+ conductance. This hyperpolarization may cause the coronary vasorelaxation by decreasing the cytoplasmic Ca2+... -
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- Effects of adenosine tetraphosphate (ATPP) on vascular tone in the isolated rat aorta
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Lee JW, Kong ID, Park KS, Jeong SW
- KMID: 699860
- Yonsei Med J.
- 1995 Dec;36(6):487-496.
- doi: 10.3349/ymj.1995.36.6.487
Effects of a platelet-released, naturally occurring nucleotide, adenosine 5'-tetraphosphate (ATPP) on vascular tone were analyzed in the isolated rat aorta. Under resting tension ATPP (1 approximately 100 microM) elicited concentration-dependent... -
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- Mechanism of UV light-induced photorelaxation in isolated rat aorta
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Kim JH, Hong Y, Shim CS
- KMID: 1094645
- J Vet Sci.
- 2000 Dec;1(2):81-86.
Isolated rat thoracic aorta which is pharmacologically precontracted by phenylephrine induces photorelaxation when exposed to long wave length UV-light. The aim of the present study was to characterize the mechanism... -
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- The Dipeptidyl Peptidase-4 Inhibitor Sitagliptin Improves Vascular Endothelial Function in Type 2 Diabetes
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Kubota Y, Miyamoto M, Takagi G, Ikeda T, Kirinoki-Ichikawa S, Tanaka K, Mizuno K
- KMID: 2157948
- J Korean Med Sci.
- 2012 Nov;27(11):1364-1370.
- doi: 10.3346/jkms.2012.27.11.1364
The vascular endothelial function is impaired in the very early stage of atherosclerosis in diabetic patients. The goal of this study was to identify the mechanism underlying the improvement in... -
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- Attenuated release of atrial natriuretic peptide and vasorelaxation in streptozotocin-induced diabetic rats
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Choi KC, Park HC, Lee J
- KMID: 1422165
- J Korean Med Sci.
- 1994 Apr;9(2):101-106.
- doi: 10.3346/jkms.1994.9.2.101
The present study was aimed at investigating the atrial natriuretic peptide (ANP) and urinary responses to acute perturbations in fluid balance and the vascular function in diabetes mellitus (DM). DM... -
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- Improvement of Endothelial Function by Amlodipine and Vitamin C in Essential Hypertension
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On YK, Kim CH, Sohn DW, Oh BH, Lee MM, Park YB, Choi YS
- KMID: 1129113
- Korean J Intern Med.
- 2002 Jun;17(2):131-137.
BACKGROUND: The effects of antihypertensive agents on endothelial function have not been fully evaluated in human hypertension and data on the forearm circulation of humans are controversial. The aim of... -
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- Cinnamyl alcohol attenuates vasoconstriction by activation of K+ channels via NO-cGMP-protein kinase G pathway and inhibition of Rho-kinase
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Kang YH, Yang IJ, Morgan KG, Shin HM
- KMID: 1402319
- Exp Mol Med.
- 2012 Dec;44(12):749-755.
Cinnamyl alcohol (CAL) is known as an antipyretic, and a recent study showed its vasodilatory activity without explaining the mechanism. Here we demonstrate the vasodilatory effect and the mechanism of... -
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- HMG-CoA Reductase Inhibitor Improves Endothelial Dysfunction in Spontaneous Hypertensive Rats Via Down-regulation of Caveolin-1 and Activation of Endothelial Nitric Oxide Synthase
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Suh JW, Choi DJ, Chang HJ, Cho YS, Youn TJ, Chae IH, Kim KI, Kim CH, Kim HS, Oh BH, Park YB
- KMID: 1713826
- J Korean Med Sci.
- 2010 Jan;25(1):16-23.
- doi: 10.3346/jkms.2010.25.1.16
Hypertension is associated with endothelial dysfunction and increased cardiovascular risk. Caveolin-1 regulates nitric oxide (NO) signaling by modulating endothelial nitric oxide synthase (eNOS). The purpose of this study was to... -
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