- Genipin Inhibits Hypoxia-Induced Accumulation of HIF-1α and VEGF Expressions in Human Cervical Carcinoma Cells
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Jin CE, Lee JH, Kim GJ, Lee TH
- KMID: 2467971
- Kosin Med J.
- 2019 Dec;34(2):106-116.
- doi: 10.7180/kmj.2019.34.2.106
OBJECTIVES: Hypoxia—a characteristic of almost all types of solid tumors—has been associated with poor outcomes in several human malignancies. Genipin—an active constituent of Gardenia fruit— has been reported to exert... -
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- Determination of Serum Vascular Endothelial Growth Factor Levels in Attention Deficit Hyperactivity Disorder: A Case Control Study
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Torun YT, Güney E, Aral A, Büyüktaşkin D, Tunca H, Taner YI, İşeri E
- KMID: 2464718
- Clin Psychopharmacol Neurosci.
- 2019 Nov;17(4):517-522.
- doi: 10.9758/cpn.2019.17.4.517
OBJECTIVE: The effect of vascular endothelial growth factor (VEGF) on neuronal development is known, but its relationship with attention deficit hyperactivity disorder (ADHD), a neurodevelopmental disorder, has not yet been... -
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- Association of serum levels of vascular endothelial growth factor and thrombospondin-1 to body mass index in polycystic ovary syndrome: a case-control study
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Tahergorabi Z, Salmani F, Jonaidabad SH, Behdani B, Yazdi P, Zardast M, Moodi M
- KMID: 2462120
- Obstet Gynecol Sci.
- 2019 Nov;62(6):420-428.
- doi: 10.5468/ogs.2019.62.6.420
PURPOSE: Polycystic ovary syndrome (PCOS) is a gynecological endocrine disorder that is characterized by disturbances in ovarian blood flow and angiogenesis. The aim of this study was to determine the... -
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- High Expression of Galectin-1, VEGF and Increased Microvessel Density Are Associated with MELF Pattern in Stage I-III Endometrioid Endometrial Adenocarcinoma
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Zinovkin D, Achinovich SL, Zubritskiy MG, Whatmore J, Pranjol MZ
- KMID: 2459576
- J Pathol Transl Med.
- 2019 Sep;53(5):280-288.
- doi: 10.4132/jptm.2019.05.13
BACKGROUND: In this study, we investigate the expression of markers of angiogenesis and microvessel density (MVD) in cases of microcystic, elongated and fragmented (MELF) pattern, with its prognostic role in... -
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- Arg-Leu-Tyr-Glu Suppresses Retinal Endothelial Permeability and Choroidal Neovascularization by Inhibiting the VEGF Receptor 2 Signaling Pathway
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Park W, Baek YY, Kim J, Jo DH, Choi S, Kim JH, Kim T, Kim S, Park M, Kim JY, Won MH, Ha KS, Kim JH, Kwon YG, Kim YM
- KMID: 2456222
- Biomol Ther.
- 2019 Sep;27(5):474-483.
- doi: 10.4062/biomolther.2019.041
Vascular endothelial growth factor (VEGF) plays a pivotal role in pathologic ocular neovascularization and vascular leakage via activation of VEGF receptor 2 (VEGFR2). This study was undertaken to evaluate the... -
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- The correlation between serum vascular endothelial growth factor (VEGF) and tumor VEGF receptor 3 in colorectal cancer
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Goulart A, Ferreira C, Rodrigues , Coimbra B, Sousa N, Leão P
- KMID: 2450985
- Ann Surg Treat Res.
- 2019 Jul;97(1):15-20.
- doi: 10.4174/astr.2019.97.1.15
PURPOSE: Despite plasma biomarkers offering a number of advantages over tissue-based markers, the relationship between serum vascular endothelial growth factor (VEGF) and VEGF receptor (VEGF-R) tumor expression in colorectal cancer... -
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- Increased expression of vascular endothelial growth factor-C and vascular endothelial growth factor receptor-3 after pilocarpine-induced status epilepticus in mice
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Cho KO, Kim JY, Jeong KH, Lee MY, Kim SY
- KMID: 2450495
- Korean J Physiol Pharmacol.
- 2019 Jul;23(4):281-289.
- doi: 10.4196/kjpp.2019.23.4.281
Vascular endothelial growth factor (VEGF)-C and its receptor, vascular endothelial growth factor receptor (VEGFR)-3, are responsible for lymphangiogenesis in both embryos and adults. In epilepsy, the expression of VEGF-C and... -
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- Angiopoietin-1 and -2 and vascular endothelial growth factor expression in ovarian grafts after cryopreservation using two methods
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Cho IA, Lee YJ, Lee HJ, Choi IY, Shin JK, Lee SA, Lee JH, Choi WJ
- KMID: 2419531
- Clin Exp Reprod Med.
- 2018 Sep;45(3):143-148.
- doi: 10.5653/cerm.2018.45.3.143
OBJECTIVE: The favored method of preserving fertility in young female cancer survivors is cryopreservation and autotransplantation of ovarian tissue. Reducing hypoxia until angiogenesis takes place is essential for the survival... -
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- Expression of vascular endothelial growth factor is a clinically useful predictor for aggressive basal cell carcinoma
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Choi JS, Lee DC, Chang HK
- KMID: 2415842
- Kosin Med J.
- 2018 Jun;33(1):75-84.
- doi: 10.7180/kmj.2018.33.1.75
OBJECTIVES: Basal cell carcinoma (BCC) tumors are locally invasive but rarely metastatic. However, aggressive metastatic variants are being increasingly reported in elderly people. Here we investigated the clinical utility of... -
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- Isomangiferin, a Novel Potent Vascular Endothelial Growth Factor Receptor 2 Kinase Inhibitor, Suppresses Breast Cancer Growth, Metastasis and Angiogenesis
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Wang B, Shen J, Wang Z, Liu J, Ning Z, Hu M
- KMID: 2441863
- J Breast Cancer.
- 2018 Mar;21(1):11-20.
- doi: 10.4048/jbc.2018.21.1.11
PURPOSE: Vascular endothelial growth factor (VEGF) signal transduction mainly depends on its binding to VEGF receptor 2 (VEGFR-2). VEGF downstream signaling proteins mediate several of its effects in cancer progression,... -
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- 20(S)-Protopanaxadiol enhances angiogenesis via HIF-1α-mediated VEGF secretion by activating p70S6 kinase and benefits wound healing in genetically diabetic mice
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Zhang EY, Gao B, Shi HL, Huang LF, Yang L, Wu XJ, Wang ZT
- KMID: 2395749
- Exp Mol Med.
- 2017 Oct;49(10):e387.
- doi: 10.1038/emm.2017.151
Impaired angiogenesis is one of the crucial factors that impede the wound healing process in diabetic foot ulcers (DFUs). In this study, we found that 20(S)-protopanaxadiol (PPD), an aglycone of... -
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- Sustained-released mixture of vascular endothelial growth factor 165 and fibrin glue strengthens healing of ileal anastomoses in a rabbit model with intraperitoneal infection
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Li Z, Wang W, Wang X, Jiang L, Wang F, Liu Q
- KMID: 2398963
- Ann Surg Treat Res.
- 2017 Sep;93(3):159-165.
- doi: 10.4174/astr.2017.93.3.159
PURPOSE: To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses. METHODS: One hundred twenty-eight... -
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- The Potential Roles of MELF-Pattern, Microvessel Density, and VEGF Expression in Survival of Patients with Endometrioid Endometrial Carcinoma: A Morphometrical and Immunohistochemical Analysis of 100 Cases
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Zinovkin D, Pranjol MZ, Petrenyov , Nadyrov EA, Savchenko
- KMID: 2392564
- J Pathol Transl Med.
- 2017 Sep;51(5):456-462.
- doi: 10.4132/jptm.2017.07.19
BACKGROUND: In this study, we hypothesized that microcystic, elongated, fragmented (MELF)-pattern, vascular endothelial growth factor (VEGF) expression by cancer cells and microvessel density of cancer stroma may be associated with... -
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- Inhibiting Vascular Endothelial Growth Factor in Injured Intervertebral Discs Attenuates Pain-Related Neuropeptide Expression in Dorsal Root Ganglia in Rats
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Sato J, Inage K, Miyagi M, Sakuma Y, Yamauchi K, Koda M, Furuya T, Nakamura J, Suzuki M, Kubota G, Oikawa Y, Sainoh T, Fujimoto K, Shiga Y, Abe K, Kanamoto H, Inoue M, Kinoshita , Norimoto M, Umimura T, Takahashi , Ohtori S, Orita S
- KMID: 2387660
- Asian Spine J.
- 2017 Aug;11(4):556-561.
- doi: 10.4184/asj.2017.11.4.556
STUDY DESIGN: An experimental animal study. PURPOSE: To evaluate effects of anti-vascular endothelial growth factor (VEGF) on the content and distribution of the calcitonin gene-related peptide (CGRP) in the dorsal ganglia... -
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- Gastric Cancer and Angiogenesis: Is VEGF a Useful Biomarker to Assess Progression and Remission?
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Macedo F, Ladeira K, Longatto-Filho A, Martins SF
- KMID: 2372577
- J Gastric Cancer.
- 2017 Mar;17(1):1-10.
- doi: 10.5230/jgc.2017.17.e1
Gastric cancer (GC) has high mortality owing to its aggressive nature. Tumor angiogenesis plays an essential role in the growth, invasion, and metastatic spread of GC. The aim of this... -
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- Clinical significance of serum vascular endothelial growth factor in young male asthma patients
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Lee HY, Min KH, Lee SM, Lee JE, Rhee CK
- KMID: 2371652
- Korean J Intern Med.
- 2017 Mar;32(2):295-301.
- doi: 10.3904/kjim.2014.242
BACKGROUND/AIMS: Vascular endothelial growth factor (VEGF) is an important mediator of angiogenesis. However, little is known about the potential use of serum levels of VEGF as a biomarker for asthma.... -
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- Serum vascular endothelial growth factor as a marker of asthma exacerbation
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Kim JH
- KMID: 2371647
- Korean J Intern Med.
- 2017 Mar;32(2):258-260.
- doi: 10.3904/kjim.2017.066
No abstract available. -
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- Vascular Endothelial Growth Factor Enhances Axonal Outgrowth in Organotypic Spinal Cord Slices via Vascular Endothelial Growth Factor Receptor 1 and 2
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Park HW, Jeon HJ, Chang MS
- KMID: 2360809
- Tissue Eng Regen Med.
- 2016 Oct;13(5):601-609.
- doi: 10.1007/s13770-016-0051-9
Enhancing adult nerve regeneration is a potential therapeutic strategy for treating spinal cord injury. Vascular endothelial growth factor (VEGF) is a major contributor to angiogenesis, which can reduce the spinal... -
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- The Effects of Vascular Endothelial Growth Factor on Capsule Formation around Silicone Implant in Rats
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Kim DH, Song YS, Song SY, Kim CH
- KMID: 2356762
- Arch Aesthetic Plast Surg.
- 2016 Oct;22(3):129-134.
- doi: 10.14730/aaps.2016.22.3.129
BACKGROUND: The purpose of this study was to examine the effects of a single administration of vascular endothelial growth factor (VEGF) in promoting the angiogenesis and thereby reducing the formation... -
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- Systemic Expression of Vascular Endothelial Growth Factor in Patients with Cerebral Cavernous Malformation Treated by Stereotactic Radiosurgery
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Park SJ, Park SH
- KMID: 2351711
- J Korean Neurosurg Soc.
- 2016 Sep;59(5):442-448.
- doi: 10.3340/jkns.2016.59.5.442
OBJECTIVE: Increased expression of angiogenic factors, such as vascular endothelial growth factor (VEGF), is associated with the pathogenesis of cerebral cavernous malformations (CCMs). The purpose of this study was to... -
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