- Suppressive role of vascular endothelial growth factor on intestinal apoptosis in induced necrotizing enterocolitis in rats
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Yang HB, Kim HY, Kim SH, Kim Sy
- KMID: 2545907
- Ann Surg Treat Res.
- 2023 Sep;105(3):157-164.
- doi: 10.4174/astr.2023.105.3.157
Purpose: Necrotizing enterocolitis (NEC) is a devastating disease that can cause mortality in preterm babies. NEC may develop through an apoptotic pathway that is known to be inhibited by vascular... -
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- Anti-vascular endothelial growth factor receptor in colorectal cancer: A review
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Colombo A, Porretto CM
- KMID: 2545060
- Int J Gastrointest Interv.
- 2023 Jul;12(3):110-114.
- doi: 10.18528/ijgii230011
In recent years, the treatment of metastatic colorectal cancer (mCRC) has dramatically changed thanks to the advent of new drugs called molecular targeted therapies such as anti-vascular endothelial growth factor... -
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- Effects of Vascular Endothelial Growth Factor on YAP/TAZ Signaling in Trabecular Meshwork Cells
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Kim SY, Sung MS, Park SW
- KMID: 2542873
- J Korean Ophthalmol Soc.
- 2023 Jun;64(6):522-531.
- doi: 10.3341/jkos.2023.64.6.522
Purpose: To investigate the effects of vascular endothelial growth factor (VEGF) on yes-associated protein (YAP)/transcriptional coactivator with a PDZ-binding motif (TAZ), a Hippo pathway-related transcription factor, and the role of... -
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- Targeted therapies in ovarian cancer: where we stand and where we are heading
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Lee TS
- KMID: 2543852
- J Korean Med Assoc.
- 2023 Jun;66(6):384-392.
- doi: 10.5124/jkma.2023.66.6.384
Background: Ovarian cancer is a highly lethal gynecological cancer globally. The standard treatment for this disease is cytoreductive surgery followed by platinum-based chemotherapy. However, most patients develop platinum resistance after... -
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- Real-World Treatment Intensity and Patterns in Patients With Myopic Choroidal Neovascularization: Common Data Model in Ophthalmology
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Bui MH, Lee DY, Park SJ, Park KH
- KMID: 2543845
- J Korean Med Sci.
- 2023 Jun;38(23):e174.
- doi: 10.3346/jkms.2023.38.e174
Background: A paucity of data addressing real-world treatment of myopic choroidal neovascularization (mCNV) in the era of anti-vascular endothelial growth factor (VEGF) drugs led us to investigate real-world treatment intensity... -
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- Exploratory Analysis of Patients With Gastric/Gastroesophageal Junction Adenocarcinoma With or Without Liver Metastasis From the Phase 3 RAINBOW Study
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Ogata T, Narita Y, Wainberg ZA, Cutsem EV, Yamaguchi K, Piao Y, Zhao Y, Peterson PM, Wijayawardana SR, Abada P, Chatterjee A, Muro K
- KMID: 2547745
- J Gastric Cancer.
- 2023 Apr;23(2):289-302.
- doi: 10.5230/jgc.2023.23.e15
Purpose: Liver metastasis (LM) is reported in approximately 40% of patients with advanced/ metastatic gastric/gastroesophageal junction adenocarcinoma (metastatic esophagogastric adenocarcinoma; mGEA) and is associated with a worse prognosis. This post-hoc... -
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- Clinicopathologic significance of the delta-like ligand 4, vascular endothelial growth factor, and hypoxia-inducible factor-2α in gallbladder cancer
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Park S, Kim J, Jang W, Kim KM, Jang KT
- KMID: 2540497
- J Pathol Transl Med.
- 2023 Mar;57(2):113-122.
- doi: 10.4132/jptm.2023.02.01
Background: Gallbladder cancer (GBC) is usually detected in advanced stages with a low 5-year survival rate. Delta-like ligand 4 (DLL4), vascular endothelial growth factor (VEGF), and hypoxia-inducible factor-2alpha (HIF2α) have... -
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- Adenosine-Prefabricated Adipose Tissue Improves Fat Graft Survival by Promoting VEGF-Dependent Angiogenesis
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Chang J, Song WJ, Soedono S, Sharlene S, Kim YJ, Choi CY, Cho KW
- KMID: 2533933
- Tissue Eng Regen Med.
- 2022 Oct;19(5):1051-1061.
- doi: 10.1007/s13770-022-00470-4
BACKGROUND: Angiogenesis plays an important role in determining the fat graft survival. However, clinical preconditioning techniques that target angiogenesis during fat grafting have not been established so far. Adenosine has... -
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- Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-Based Regimens
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Kourea HP, Dimitrakopoulos FI, Koliou GA, Batistatou A, Papadopoulou K, Bobos M, Asimaki-Vlachopoulou A, Chrisafi S, Pavlakis K, Chatzopoulos K, Galani E, Pentheroudakis G, Pectasides D, Bafaloukos D, Res E, Papakostas P, Koutras A, Kotoula V, Fountzilas G
- KMID: 2534184
- Cancer Res Treat.
- 2022 Oct;54(4):1053-1064.
- doi: 10.4143/crt.2021.748
Purpose Angiogenesis is a crucial phenomenon in the development and progression of breast cancer (BC), but the clinical significance of angiogenesis-related proteins in metastatic BC remains unknown. This study investigates... -
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- The Roles of Vascular Endothelial Growth Factor, Angiostatin, and Endostatin in Nasal Polyp Development
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Hong TU, Park SK
- KMID: 2532009
- J Rhinol.
- 2022 Jul;29(2):82-87.
- doi: 10.18787/jr.2021.00400
Background and Objectives: Microvascular remodeling and angiogenesis are elements of tissue remodeling characteristic of chronic inflammatory diseases, including nasal polyps (NPs). Angiogenesis reflects the balance between the actions of pro-... -
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- Comparison of Each Retinal Layer Thicknesses between Eyes with Central Retinal Vein Occlusion and Normal Contralateral Eyes
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Yu HY, Lee MW, Kim JT, Lee SC, Lee YH
- KMID: 2530594
- Korean J Ophthalmol.
- 2022 Jun;36(3):274-281.
- doi: 10.3341/kjo.2021.0174
Purpose: To evaluate the difference in each retinal layer thickness in central retinal vein occlusion (CRVO) with resolved macular edema after intravitreal antivascular endothelial growth factor injection and normal contralateral... -
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- A Case of Iris Neovascularization in Severe Fungal Keratitis Treated with Intracameral Bevacizumab
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Lim YJ, Cho CH
- KMID: 2530262
- J Korean Ophthalmol Soc.
- 2022 May;63(5):472-477.
- doi: 10.3341/jkos.2022.63.5.472
Purpose: We report a case in which iris neovascularization (NVI) improved after intracameral bevacizumab injection in a patient who exhibited fungal keratitis with NVI. Case summary: A 47-year-old man experienced a... -
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- Update on the POEMS syndrome
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Kim YR
- KMID: 2529303
- Blood Res.
- 2022 Apr;57(S1):S27-S31.
- doi: 10.5045/br.2022.2022001
POEMS syndrome is an acronym for polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin changes. It is a rare paraneoplastic disorder related to plasma cell neoplasm. However, its pathophysiology has not... -
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- Retinopathy of prematurity: a review of epidemiology and current treatment strategies
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Hong EH, Shin YU, Cho H
- KMID: 2527123
- Clin Exp Pediatr.
- 2022 Mar;65(3):115-126.
- doi: 10.3345/cep.2021.00773
Retinopathy of prematurity (ROP) is among the most common causes of childhood blindness. Three phases of ROP epidemics have been observed worldwide since ROP was first described in the 1940s.... -
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- Intraocular Cytokine Changes in Patients with Polypoidal Choroidal Vasculopathy Treated with Ranibizumab
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Choi Y, Kim SH, Choi SK, Lee JJ, Lee SM, Kwon HJ, Park SW, Lee JE, Byon IS
- KMID: 2526506
- J Korean Ophthalmol Soc.
- 2022 Feb;63(2):166-174.
- doi: 10.3341/jkos.2022.63.2.166
Purpose: To investigate the changes in intraocular cytokines after ranibizumab treatment in patients with polypoidal choroidal vasculopathy (PCV). Methods: This multicenter, prospective study enrolled patients with PCV treated with three monthly... -
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- The role of hesperidin in ameliorating retinal changes in rats with experimentally induced type 1 diabetes mellitus and the active role of vascular endothelial growth factor and glial fibrillary acidic protein
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Shehata AS, Mohamed DA, Hagras SM, El-Beah SM, Elnegris HM
- KMID: 2523577
- Anat Cell Biol.
- 2021 Dec;54(4):465-478.
- doi: 10.5115/acb.21.105
Patients with type 1 diabetes mellitus (T 1 DM) are vulnerable to developing diabetic retinopathy even under insulin therapy. Thus, this study was designed to evaluate the efficacy of hesperidin... -
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- Osteogenic and Angiogenic Potency of VEGF165-Transfected Canine Bone Marrow Mesenchymal Cells Combined with Coral Hydroxyapatite in Vitro
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Zhang Q, Zhang J, Chen L, Fan Y, Long J, Liu S
- KMID: 2520645
- Tissue Eng Regen Med.
- 2021 Oct;18(5):875-886.
- doi: 10.1007/s13770-021-00368-7
BACKGROUND: To explore the osteogenic and angiogenic potential of human vascular endothelial growth factor 165 (hVEGF165) gene-transfected canine bone marrow mesenchymal stem cells (BMSCs) combined with coral hydroxyapatite (CHA) scaffold. METHODS: We constructed... -
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- Therapeutic efficiency of adipose-derived mesenchymal stem cells in healing of experimentally induced gastric ulcers in rats
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Hassan SA, Abou Elghait AT, Abdelqader ZS, Meligy FY
- KMID: 2521049
- Anat Cell Biol.
- 2021 Sep;54(3):361-374.
- doi: 10.5115/acb.21.034
Gastric (peptic) ulcer is a major gastrointestinal disorder with high morbidity and mortality. While several drugs have been used to treat gastric ulcers, such as proton pump inhibitor-based triple therapy... -
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- Real Life Data of Treat and Extend Intravitreal Ranibizumab and Aflibercept Therapy in Wet Age-related Macular Degeneration Patients: 3-Year Results
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Ugurtay O, Kockar A, Sengul EA
- KMID: 2518972
- Korean J Ophthalmol.
- 2021 Aug;35(4):280-286.
- doi: 10.3341/kjo.2020.0109
Purpose: To compare functional and anatomic outcome of intravitreal ranibizumab (IVR) and intravitreal aflibercept (IVA) treatments in neovascular age-related macular degeneration by using the treat and extend (TE) protocol. Methods: In... -
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- Effects of quercetin on cell differentiation and adipogenesis in 3T3-L1 adipocytes
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Hong SY, Ha AW, Kim W
- KMID: 2518753
- Nutr Res Pract.
- 2021 Aug;15(4):444-455.
- doi: 10.4162/nrp.2021.15.4.444
BACKGROUND/OBJECTIVES: Adipocytes undergo angiogenesis to receive nutrients and oxygen needed for adipocyte' growth and differentiation. No study relating quercetin with angiogenesis in adipocytes exists. Therefore, this study investigated the role... -
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