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Sex-specific relationship between vascular calcification and incident fracture in patients with end-stage renal disease

Nam YJ, Hwang SY, Kim DW, Kim D, Shin SJ, Yoon HE

Background: Vascular calcification (VC) is a major component of mineral bone disorders in patients with end- stage renal disease (ESRD). Bone metabolism is affected by various factors, including sex hormones. This...
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Regulatory Effects of O-GlcNAcylation in Vascular Smooth Muscle Cells on Diabetic Vasculopathy

Byon CH, Kim SW

Vascular complications from uncontrolled hyperglycemia are the leading cause of death in patients with diabetes mellitus. Previous reports have shown a strong correlation between hyperglycemia and vascular calcification, which increases...
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Associations of Perirenal Fat Thickness with Renal and Systemic Calcified Atherosclerosis

Koo BK, Denenberg , Wright CM, Criqui MH, Allison MA

BACKGROUND: We investigated associations between perirenal fat thickness and atherosclerotic calcification in six different vascular beds. METHODS: Using a community-based cohort (n=3,919), perirenal fat thickness was estimated from computed tomography scans....
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The function of zinc in the primary vascular smooth muscle cell proliferation in rats

Cho YE, Kwun IS

Purpose: The vascular smooth muscle cells (VSMCs) in mature animals have implicated to play a major role in the progression of cardiovascular diseases such as atherosclerosis. This study aimed at...
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Impacts of Coronary Artery Calcification on Intradialytic Blood Pressure Patterns in Patients Receiving Maintenance Hemodialysis

Yeo S, Moon JI, Shin J, Hwang JH, Cho I, Kim SH

Intradialytic blood pressure abnormalities are associated with adverse outcomes in patients with end-stage renal disease on dialysis. Vascular calcification is a common complicating feature, but whether this complication results in...
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Supplementary nutrients for prevention of vascular calcification in patients with chronic kidney disease

Lee SM, An WS

Vascular calcification (VC) and malnutrition associated with cardiovascular disease are common in patients with chronic kidney disease (CKD) treated with dialysis. VC, which reflects vascular aging, and malnutrition are also...
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Vascular Calcification in Patients with Chronic Kidney Disease

Jung JY

Cardiovascular morbidity and mortality are very common in patients with chronic kidney disease, which may result in part from vascular calcification. Vascular calcification requires osteoblastic trans-differentiation of vascular smooth muscle...
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Serum myostatin levels are associated with abdominal aortic calcification in dialysis patients

Lee SM, Kim SE, Lee JY, Jeong HJ, Son YK, An WS

BACKGROUND: Serum myostatin levels are increased according to renal function decline and myostatin may be a main mediator of chronic kidney disease–related sarcopenia. A previous study reported that serum myostatin...
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A Comparison of Aortoiliac Disease between Eastern and Western Countries

Joh JH, Cho S

A variety of diseases are known to develop in the aortoiliac segment; these include abdominal aortic aneurysm (AAA) and aortoiliac occlusive disease. This review summarizes several differences of aortoiliac diseases...
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Intracranial Arterial Calcificationes Can Reflect Cerebral Atherosclerosis Burden

Kim JM, Park KY, Bae JH, Han SH, Jeong HB, Jeong D

BACKGROUND AND PURPOSE: We investigated whether the intracranial arterial calcification status reflects the overall cerebral atherosclerosis burden. METHODS: Patients with acute cerebral infarction who were admitted to a single university hospital...
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Pre-existing arterial pathologic changes affecting arteriovenous fistula patency and cardiovascular mortality in hemodialysis patients

Lee JY, Kim YO

The radiocephalic arteriovenous fistula (AVF) provides optimal vascular access for hemodialysis; it has a higher long-term patency rate and fewer complications than other vascular access methods. However, the AVF has...
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The Impact of Arterial Micro-calcification of the Vascular Access on Coronary Artery Calcification and Cardiovascular Mortality in Incident Hemodialysis Patients

Lee YB, Choi BM, Hwang HS, Park HS, Park SC, Kim YO

BACKGROUND/AIMS: The aim of this study was to explore the relationship between arterial micro-calcification (AMiC) and coronary artery calcification, and to determine the impact of AMiC on cardiovascular mortality in...
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Lethal Outcome due to Misdiagnosis between Acute Cerebral Infarction and Epidural Hematoma Expansion after Blunt Trauma: A Case Report

Yun JH

Large amount of epidural hematoma usually requires surgical intervention. When the amount of epidural hematoma is increasing gradually, causing neurological symptoms, an early emergent surgery may be the only way...
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Chronic Kidney Disease-Mineral Bone Disorder in Korean Patients: a Report from the KoreaN Cohort Study for Outcomes in Patients With Chronic Kidney Disease (KNOW-CKD)

Kim CS, Bae EH, Ma SK, Han SH, Lee KB, Lee J, Oh KH, Chae DW, Kim SW, Representatives of the KNOW-CKD Study Group

This study examined the characteristics of biochemical parameters, bone diseases, and vascular calcification in Korean patients with chronic kidney disease (CKD) not yet on dialysis. Serum levels of fibroblast growth...
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Prognostic Application of Thoracic Aortic Calcium Scoring for Adverse Clinical Outcome Risk in Elderly Patients with Left Ventricular Hypertrophy

Cho IJ, Chang HJ, Lee SE, Shim CY, Hong GR, Chung N

BACKGROUND AND OBJECTIVES: Left ventricular hypertrophy (LVH) is associated with poor cardiovascular outcomes. Heavy aortic calcification exacerbates arterial stiffness, which consequently heightens left ventricular (LV) afterload. We assessed the usefulness...
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New Aspects of Vascular Calcification: Histone Deacetylases and Beyond

Kwon DH, Kim YK, Kook H

Vascular calcification is a pathologic phenomenon in which calcium phosphate is ectopically deposited in the arteries. Previously, calcification was considered to be a passive process in response to metabolic diseases,...
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Mechanisms of Vascular Calcification: The Pivotal Role of Pyruvate Dehydrogenase Kinase 4

Leem J, Lee IK

Vascular calcification, abnormal mineralization of the vessel wall, is frequently associated with aging, atherosclerosis, diabetes mellitus, and chronic kidney disease. Vascular calcification is a key risk factor for many adverse...
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Radiographic manifestations of Mönckeberg arteriosclerosis in the head and neck region

Tahmasbi-Arashlow M, Barghan S, Kashtwari , Nair MK

Mönckeberg sclerosis is a disease of unknown etiology, characterized by dystrophic calcification within the arterial tunica media of the lower extremities leading to reduced arterial compliance. Medial calcinosis does not...
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Relationship between Framingham Risk Score and Coronary Artery Calcium Score in Asymptomatic Korean Individuals

Heo SY, Park NH, Park CS, Seong SO

PURPOSE: We explored the association between Framingham risk score (FRS) and coronary artery calcium score (CACS) in asymptomatic Korean individuals. MATERIALS AND METHODS: We retrospectively analyzed 2216 participants who underwent routine...
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Coronary Calcification Is Reversely Related with Bone and Hair Calcium: The Relationship among Different Calcium Pools in Body

Lee SH, Park SJ, Kim KN, Cho DY, Kim YS, Kim BT

BACKGROUND: With aging, calcium efflux from bone is increased with age-related bone loss, and it can reduce bone mineral density (BMD). On the contrary, age-related calcium adoption into arterial wall...
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