- Extract of Curcuma zedoaria R. prevents atherosclerosis in apolipoprotein E-deficient mice
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Kim KM, Lee JY, Jeon BH, Quan KT, Na M, Nam KW, Chae S
- KMID: 2516071
- Nutr Res Pract.
- 2021 Jun;15(3):319-328.
- doi: 10.4162/nrp.2021.15.3.319
BACKGROUND/OBJECTIVES: Curcuma zedoaria R. (Zingiberaceae) has been used to treat headache, fever, and hypertension-related symptoms in Asian countries, including Korea, China, and Japan. We investigated whether dietary intake of a... -
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- Exploration of the developmental process of vasculogenic mimicry in canine inflammatory mammary carcinoma
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Choi JS, Oh YI, Lee BW, Kim HW, Yoon BI
- KMID: 2503835
- J Biomed Transl Res.
- 2020 Jun;21(2):95-99.
- doi: 10.12729/jbtr.2020.21.2.095
Canine inflammatory mammary carcinoma (CIMC) similar to human inflammatory breast cancer is a very aggressive, metastatic type of cancer. Previous studies have introduced a new type of tumor angiogenesis called... -
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- Lobaric Acid Inhibits VCAM-1 Expression in TNF-alpha-Stimulated Vascular Smooth Muscle Cells via Modulation of NF-kappaB and MAPK Signaling Pathways
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Kwon IS, Yim JH, Lee HK, Pyo S
- KMID: 2170537
- Biomol Ther.
- 2016 Jan;24(1):25-32.
- doi: 10.4062/biomolther.2015.084
Lichens have been known to possess multiple biological activities, including anti-proliferative and anti-inflammatory activities. Vascular cell adhesion molecule-1 (VCAM-1) may play a role in the development of atherosclerosis. Hence, VCAM-1... -
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- Nafamostat Mesilate Inhibits TNF-alpha-Induced Vascular Endothelial Cell Dysfunction by Inhibiting Reactive Oxygen Species Production
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Kang MW, Song HJ, Kang SK, Kim Y, Jung SB, Jee S, Moon JY, Suh KS, Lee SD, Jeon BH, Kim CS
- KMID: 1791423
- Korean J Physiol Pharmacol.
- 2015 May;19(3):229-234.
- doi: 10.4196/kjpp.2015.19.3.229
Nafamostat mesilate (NM) is a serine protease inhibitor with anticoagulant and anti-inflammatory effects. NM has been used in Asia for anticoagulation during extracorporeal circulation in patients undergoing continuous renal replacement... -
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- Ginsenoside Rg2 Inhibits Lipopolysaccharide-Induced Adhesion Molecule Expression in Human Umbilical Vein Endothelial Cell
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Cho YS, Kim CH, Ha TS, Lee SJ, Ahn HY
- KMID: 1429384
- Korean J Physiol Pharmacol.
- 2013 Apr;17(2):133-137.
- doi: 10.4196/kjpp.2013.17.2.133
Vascular cell adhesion molecule 1 (VCAM-1), intercellular adhesion molecule 1 (ICAM-1), P- and E-selectin play a pivotal role for initiation of atherosclerosis. Ginsenoside, a class of steroid glycosides, is abundant... -
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- Lactosylceramide Mediates the Expression of Adhesion Molecules in TNF-alpha and IFNgamma-stimulated Primary Cultured Astrocytes
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Lee JK, Kim JK, Park SH, Sim YB, Jung JS, Suh HW
- KMID: 2071726
- Korean J Physiol Pharmacol.
- 2011 Oct;15(5):251-258.
- doi: 10.4196/kjpp.2011.15.5.251
Here we have investigated how lactosylceramide (LacCer) modulates gene expression of adhesion molecules in TNF-alpha and IFNgamma (CM)-stimulated astrocytes. We have observed that stimulation of astrocytes with CM increased the... -
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- Heparin Attenuates the Expression of TNF alpha-induced Cerebral Endothelial Cell Adhesion Molecule
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Lee JH, Kim CH, Seo GH, Lee J, Kim JH, Kim DG, Ahn YS
- KMID: 1486104
- Korean J Physiol Pharmacol.
- 2008 Oct;12(5):231-236.
- doi: 10.4196/kjpp.2008.12.5.231
Heparin is a well-known anticoagulant widely used in various clinical settings. Interestingly, recent studies have indicated that heparin also has anti-inflammatory effects on neuroinflammation-related diseases, such as Alzheimer's disease and... -
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- Synergistic Efficacy of Concurrent Treatment with Cilostazol and Probucol on the Suppression of Reactive Oxygen Species and Inflammatory Markers in Cultured Human Coronary Artery Endothelial Cells
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Park SY, Lee JH, Shin HK, Kim CD, Lee WS, Rhim BY, Shin YW, Hong KW
- KMID: 1838354
- Korean J Physiol Pharmacol.
- 2008 Aug;12(4):165-170.
- doi: 10.4196/kjpp.2008.12.4.165
In the present study, we aimed to identify the synergistic effects of concurrent treatment of low concentrations of cilostazol and probucol to inhibit the oxidative stress with suppression of inflammatory... -
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- The clinical feature and pathogenesis of gastroduodenal lesion in patients with scrub typhus
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Park JY, Cho MS, Shim KN, Lee YJ, Choi HJ
- KMID: 2256197
- Korean J Med.
- 2008 Jun;74(6):648-657.
BACKGROUND/AIMS: The aim of the study was to investigate the gastric involvement of Orientia tsutsugamushi and the relationship between the clinical features and gastritis in patients with scrub typhus. METHODS: The... -
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- Resveratrol blunts tumor necrosis factor-alpha-induced monocyte adhesion and transmigration
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Kim DS, Kwon HM, Choi JS, Kang SW, Ji GE, Kang YH
- KMID: 2313328
- Nutr Res Pract.
- 2007 Dec;1(4):285-290.
The leukocyte recruitment and transmigration across the endothelial barrier into the vessel wall are crucial steps in atherosclerosis. Leukocyte trafficking on the endothelium is elicited by induction of endothelial adhesion... -
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- Ascochlorin Derivative, AS-6, Inhibits TNF-alpha-Induced fractalkine, MCP-1 and VCAM-1 Expression in Rat Aortic Smooth Muscle Cells
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Jang YY, Kim SY, Kim NK, Kim MK, Kim HK, Kim HS, Nam CW, Ryu SY, Nam SI, Park KG
- KMID: 2008232
- J Korean Diabetes Assoc.
- 2005 Sep;29(5):401-408.
BACKGOUND: Inflammation is one of the key mechanisms in the development and progression of atherosclerosis. Accumulating evidence suggests that peroxisome proliferators- activated receptorgamma(PPARgamma) plays an important role in the prevention... -
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- The Clinical Significance of Soluble Intercellular Adhesion Molecule-1 (sICAM-1) and Soluble Vascular Cell Adhesion Molecule-1 (sVCAM-1) in Kawasaki Disease
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Rhee KW, Yun SW, Lee DK, Choi ES, Yoo BH, Lee MK
- KMID: 1763544
- Korean J Pediatr.
- 2005 Jun;48(6):640-648.
PURPOSE: Kawasaki disease (KD) is known as an acute multi-systemic vasculitis with various immunologic abnormalities. Adhesion of leukocyte to endothelial cells is a key event in the sequence of inflammatory... -
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- Enhanced Expression of Cell Adhesion Molecules in the Aorta of Diabetic Mice is Mediated by gp91phox-derived Superoxide
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Yun MR, Kim JJ, Lee SM, Heo HJ, Bae SS, Kim CD
- KMID: 2285317
- Korean J Physiol Pharmacol.
- 2005 Apr;9(2):109-115.
Endothelial activation and subsequent recruitment of inflammatory cells are important steps in atherogenesis. The increased levels of cell adhesion molecules (CAM) have been identified in diabetic vasculatures, but the underlying... -
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- The Activity of sICAM-1 and sVCAM-1 in Plasma of Preeclamptic Mother and Neonatal Cord Blood
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Ryu KH, Choi SD, Kim HH, Lee HS, Lee JH, Lee HS, Kim SY, Sung IK, Lee WB, Chun CS
- KMID: 2188626
- J Korean Soc Neonatol.
- 2004 May;11(1):35-43.
PURPOSE: Current concepts of preeclampsia have been focused on dysfunction of the maternal vascular endothelium, a central pathogenetic feature of the disease. But it is uncertain whether maternal preeclampsia has... -
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- Elevated Serum Level of Soluble VCAM-1 in Patients with Type 2 Diabetes Mellitus with Overt Nephropathy
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Seo JW, Min WK, Kim YM, Kwon SK, Kim SH, Lee JI, Chang JW, Yang WS, Park SK
- KMID: 1610149
- Korean J Nephrol.
- 2003 May;22(3):294-302.
BACKGROUND: Soluble adhesion molecules including soluble vascular cell adhesion molecule-1 (sVCAM-1) are released during an infalmmatory process such as artherosclerosis. Elevated sVCAM-1 also has been reported in diabetic nephropathy. But,... -
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- ICAM-1 and VCAM-1 on Human Umbilical Vein Endothelial Cells Infected by Hantaan Virus
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Seol MJ, Kang ET, Lee TW, Kim CH, Choi JY, Yoo SJ, Oh DJ, Yu SH
- KMID: 1889319
- Korean J Nephrol.
- 2002 Sep;21(5):706-712.
PURPOSE: Hemorrhagic fever with renal syndrome (HFRS) is an acute febrile disease caused by Hantaan virus. It is believed that various kinds of inflammatory mediators and cytokines might be involved... -
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- Allicin Reduces Adhesion Molecules and NO Production Induced by gamma irradiation in Human Endothelial Cells
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Son EW, Cho CK, Pyo SN
- KMID: 1571386
- Immune Netw.
- 2002 Mar;2(1):6-11.
- doi: 10.4110/in.2002.2.1.6
BACKGROUND: Inflammation is a frequent reaction following therapeutic irradiation. Since the upregulation of adhesion molecules on endothelial cell surface is known to be associated with inflammation, the expression of adhesion... -
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- Predictive Value of an Immunohistochemical Staining for HLA-DR, ICAM-1 and VCAM-1 in Acute Renal Allograft Rejection
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Kim WS, Lee WM, Park CH, Kang CM, Kwak JY, Park MH
- KMID: 2198972
- J Korean Soc Transplant.
- 2001 Dec;15(2):151-157.
PURPOSE: We have evaluated the diagnostic and predictive value of HLA-DR, ICAM-1 and VCAM-1 expression in patients clinically suspected with acute rejection. METHODS: Immunohistochemical staining for HLA-DR, ICAM-1 and VCAM-1 was... -
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- Increased Expression of ICAM-1 and VCAM-1 in Human Lupus Nephritis
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Park SB, Han SM, Park KK, Kim HC
- KMID: 2079202
- Korean J Nephrol.
- 2001 Nov;20(6):997-1003.
Intercellular adhsion molecule-1(ICAM-1) and vascular cell adhension molecule-1(VCAM-1) are important cell-surface glycoprotein regulating interactions among immune cells, such as accessory and T cells. Recently, the cDNA encoding the ICAM-1 and... -
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- Effect of High Glucose on the Expression of MCP-1 and VCAM-1 in Cultured Human Peritoneal Mesothelial Cells
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Lee JS, Kim SB, Lee SK, Yu SH, Park JS
- KMID: 1989742
- Korean J Nephrol.
- 2001 May;20(3):362-374.
BACKGROUND: High glucose in peritoneal dialysis solution has been implicated in the pathogenesis of peritoneal fibrosis. Macrophages in peritoneal cavity seem to participate in the process of peritoneal fibrosis through... -
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