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Analysis of Clinical Utility of Urine Sediments

Lee AJ, Kim SG, Jeon CH

Background: In this study, after reporting the urine sediment, the clinical utility of the results was analyzed to broaden the clinical usefulness of urine sediment. Methods: This study included 114 patients...
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Evaluation of porcine urine-derived cells as nuclei donor for somatic cell nuclear transfer

Zhang YT, Yao W, Chai MJ, Liu WJ, Liu Y, Liu ZH, Weng XG

Background: Somatic cell nuclear transfer (SCNT) is used widely in cloning, stem cell research, and regenerative medicine. The type of donor cells is a key factor affecting the SCNT efficiency. Objectives:...
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Clinical Significance of Rab27a as a Urinary Biomarker in Patients With Bladder Cancer

Ku JY, Hwang EC, Lee CH, Kim KH, Kwon DD, Ha HK

Purpose: The aims of this study were to investigate the clinical value of Rab27a as a urinary biomarker, and its efficiency in the prediction of bladder cancer grade. Materials and Methods:...
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A study to evaluate the safety of iodine intake levels in women of childbearing age: 2013–2015 Korea National Health and Nutrition Examination Survey

Lee JS

Purpose This study was conducted to evaluate the safety of iodine intake based on ingestion levels and urinary iodine excretion of women of childbearing age (15–45 years old) using data from...
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Evaluation of Five Automated Urine Analyzers as Screening Instruments for Enhancing Diagnostic Efficiency in Urinary Tract Infection

Cho J, Byun JH, Lee SG, Oh K, Jeon B, Yong D, Kim JH

Background: Although urine culture is considered a reference standard for the diagnosis of urinary tract infection (UTI), it is time-consuming, labor-intensive, and expensive. Here, we evaluated the performance of five...
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Single random measurement of urinary gonadotropin concentration for screening and monitoring girls with central precocious puberty

Lee SY, Kim JM, Kim YM, Lim HH

Purpose: The gold standard for assessing pubertal activation is the gonadotropinreleasing hormone (GnRH) stimulation test (GnRHST), which is invasive, timeconsuming, and inconvenient. This study evaluated whether a single random measurement...
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Secondhand Smoke Exposure and Dysglycemia

Bak SJ, Sa HJ, Oh EJ, Kweon HJ, Kim KJ, Shin J, Choi JK

Background: This study aimed to investigate the association between the exposure to secondhand smoke (SHS) and dysglycemia. Methods: This cross-sectional study included a total of 4,417 adults (1,103 with SHS exposure,...
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A Study for Accurate Reporting of Bacteria in Urine by Manual Microscopic Examination

Jeon YL, Lee WI, Kang SY, Kim MH

Background: Since there is no standardized criterion for the semi quantitation of bacteria in manual microscopic examination, activities for reducing the subjectiveness of manual microscopic examination for detecting urinary bacteria...
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Performance and Diagnostic Accuracy of Human Papillomavirus Testing on Self-Collected Urine and Vaginal Samples in a Referral Population

Cho HW, Hong JH, Min KJ, Ouh YT, Seong SJ, Moon JH, Cho SH, Lee JK

Purpose The study aimed to evaluate the diagnostic accuracy of polymerase chain reaction ‒based high-risk human papillomavirus (HPV) assays on self-collected vaginal and urine samples for detection of precancerous cervical...
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Availability of urine toxicologic screening tests in the emergency department: focused on illegal drugs

Lee SK, Choi S

Purpose: In Korea, it is predicted that the proportion of drug abusers among patients visiting the emergency room will soon increase. Several emergency medical institutions in Korea are conducting field...
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Effect of urinary angiotensinogen and high-salt diet on blood pressure in patients with chronic kidney disease: results from the Korean Cohort Study for Outcome in Patients with Chronic Kidney Disease (KNOW-CKD)

Kim HY, Choi HS, Kim CS, Bae EH, Ma SK, Sung SA, Han SH, Oh KH, Ahn C, Kim SW

Background/Aims: This study aimed to investigate whether urinary angiotensinogen (UAGT) excretion was associated with elevated blood pressure in patients with chronic kidney disease (CKD) and to evaluate the relationship among...
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Urinary Extracellular Vesicles as Biomarkers of Kidney Disease

Sun IO

Extracellular vesicles (EVs) are membrane-bound vesicles produced and released into the extracellular fluid by cells under physiological and stressful conditions. They play a role as intracellular communicators by carrying and...
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Effectiveness of Plasma and Urine Neutrophil Gelatinase-Associated Lipocalin for Predicting Acute Kidney Injury in High-Risk Patients

Yi A, Lee CH, Yun YM, Kim H, Moon HW, Hur M

Background: Neutrophil gelatinase-associated lipocalin (NGAL) is a useful biomarker for acute kidney injury (AKI) prediction. However, studies on whether using both plasma NGAL (PNGAL) and urine NGAL (UNGAL) can improve...
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Analysis of Matrix Effect of Urine Quality Control Materials in Urine Chemistry Tests

Jeon CH, Kim SG

Background: The National External Quality Assessment Service on urinalysis in Korea has used control materials manufactured by YD (YD Diagnostics, Korea). These materials are composed of phosphate-buffered saline mixed with...
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Urinary Biomarker in Bladder Cancer at Present Time

Kim SH, Lee HH, Seo HK

Current standard diagnostic modality of bladder cancer is cystoscopy with/without urine cytology from patient’s voided urine. Considering several cystoscopic disadvantages such as symptomatic invasiveness and operatordependency, urinary cytology is an...
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Changes in Urine Osmolal Concentration with Lithium Treatment in Children and Youth with Bipolar Disorder

Jeong JW, Choi BS, Kim DW, Yu ER, Huh SY, Kim SG, Kim JH

Objectives Bipolar disorder has a high rate of recurrence, which can cause problems such as declines in cognitive and social functions. Lithium is the primary medication for preventing recurrence, but the...
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Urinary Biomarkers for Neurodegenerative Diseases

Seol Wg, Kim Hj, Son Ih

  • KMID: 2508469
  • Exp Neurobiol.
  • 2020 Oct;29(5):325-333.
  • doi: 10.5607/en20042
Global incidence of neurodegenerative diseases (NDDs) such as Alzheimer’s disease (AD) and Parkinson’s disease (PD) is rapidly increasing, but the diagnosis of these diseases at their early stage is challenging....
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Comparison of outcomes according to urine chemistry testing time for the causes of acute kidney injury patients admitted to the emergency room

Min DK, Yoon SH, Yun SR, Ryu HS, Park SS, Lim DM, Hwang WM, Lee JG

  • KMID: 2511358
  • J Korean Soc Emerg Med.
  • 2020 Oct;31(5):458-465.
Objective: The rapid identification and treatment of an acute kidney injury (AKI) can help to restore the kidney function. To differentiate between pre-renal AKI and intrinsic AKI, a urine chemistry...
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Comparison of IRIS Iq200, UF-1000i, and Cobas u701 Module Automated Urine Sediment Analyzers

Choi H, Yang D, Kwon SJ, Kang PR, Park H, Kim T, Hwang H

Background: We sought to compare the performance of three commercially available automated urine sediment analyzers that represent the current urine sediment analysis technology. Methods: A total of 232 patient samples were...
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Urine biomarkers for monitoring acute kidney injury in premature infants

Ahn YH, Lee J, Chun J, Jun YH, Sung TJ

Background: Premature infants are at high risk for acute kidney injury (AKI). Serum creatinine (Cr) has limitations for evaluating kidney function in premature infants. We evaluated whether urine biomarkers could...
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