- The Protective Effect of Mannitol and Methylprednisolone in the Acute Focal Cerebral Ischemia in Cats
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Shin KM
- KMID: 2170822
- Ewha Med J.
- 1988 Dec;11(4):283-297.
- doi: 10.12771/emj.1988.11.4.283
It is the purpose of the this experimental study to investigate the protective effect of pretreatment of mannitol and methylprednisolone(MP) on the changes of the high-energy metabolites(nucleotides ; derivatives of... -
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- A Case of Gilbert's Syndrome with Severe Neonatal Hyperbilirubinemia
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Hong YS, Jin JY, Lee WR
- KMID: 2321501
- J Korean Soc Neonatol.
- 2010 Nov;17(2):266-269.
Gilbert's syndrome is caused by a reduction in the activity of uridine diphosphate glucuronosyltransferase (UGT) and induces chronic, non-hemolytic unconjugated hyperbilirubinemia. It has been suggested that 3-10% of the population... -
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- Asymmetrical distribution of P2Y nucleotide receptors in rabbit inner medullary collecting duct cells
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Woo JS, Jung JS, Kim YK
- KMID: 1917024
- Korean J Physiol Pharmacol.
- 2000 Aug;4(4):311-318.
We cultured the rabbit inner medullary collecting duct (IMCD) cells as monolayers on collagen-coated membrane filters, and investigated distribution of the P2Y receptors by analyzing nucleotide-induced short circuit current (Isc) responses. Exposure to... -
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- Effects of Uridine 5'-Triphosphate on the Vascular Tone of Rat Thoracic Aorta
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Park KS, Kong ID, Lee JW
- KMID: 2228958
- Korean Circ J.
- 1995 Feb;25(1):68-77.
- doi: 10.4070/kcj.1995.25.1.68
BACKGROUND: Uracil nucleotides are stored in platelets and all other cells, and are released into the extracellular space upon stimulation. They show various biological responses but their actions and mechanism... -
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- Intrahepatic Arterio-Venous Shunts in a Patient with Hypergalactosemia Detected by Neonatal Screening
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Hong JH, Um JP, Cha BH, Lim BK, Kim JS
- KMID: 2188642
- J Korean Soc Neonatol.
- 2004 May;11(1):87-92.
We report a case of 15 days old newborn presenting with hypergalactosemia detected by newborn screening who had intrahepatic arterio-venous shunts with multiple pin-head sized cutaneous hemangiomas. Plasma level of... -
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- The relationship between Gly71Arg and TATA box polymorphism of UGT1A1 gene and prolonged hyperbilirubinemia of breast milk feeding infant in Korean
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Lee JM, Han YJ, Kim JS, Kim ER
- KMID: 2280223
- Korean J Pediatr.
- 2008 Feb;51(2):150-155.
- doi: 10.3345/kjp.2008.51.2.150
PURPOSE: It has been known that breast milk cause prolonged unconjugated hyperbilirubinemia. UGT1A1 is a important gene of uridine diphosphate glucuronosyltransferase (UGT) which has a major role of bilirubin metabolism.... -
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- A Case of Infantile Hepatic Hemangioendothelioma Incidentally Detected during the Evaluation of Galactosemia
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Lim RK, Byun SY, Park SS, Kim YD
- KMID: 2144479
- J Korean Soc Neonatol.
- 2010 May;17(1):136-140.
Galactosemia is a group of inherited enzyme deficiencies characterized by increase in the blood galactose levels. This condition may be associated with deficiencies of galactose-1-phosphate uridyl transferase, galactokinase, or uridine... -
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- The Efficacy of UGT1A1 Polymorphism in Chemoradiation Therapy Using Irinotecan in Patients with Locally Advanced Rectal Cancer
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Oh SY, Kim YB, Chun MS, Suh KW
- KMID: 2334401
- J Korean Soc Coloproctol.
- 2007 Oct;23(5):344-349.
PURPOSE: Irinotecan (CPT-11) is hydrolyzed to an active SN-38, which is further detoxicated to SN-38G through conjugation by uridine diphosphate glucuronosyltransferase 1A1 (UGT1A1) enzymes. There are many reports that UGT1A1... -
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- Activation of the Cardiac ATP-Sensitive K+Channel by KR-30816,Newly Synthesized Potassium Channel Opener
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Rhee KS, Ko JK, Kwak YG, Chae SW
- KMID: 2228983
- Korean Circ J.
- 1994 Dec;24(6):889-898.
- doi: 10.4070/kcj.1994.24.6.889
BACKGROUND: The effects of a newly synthesized potassium channel opener, KR-30816((-)(nitro-2-hydroxymethyl-2-methy-2H-1-benzopyran-4-y1)pyridine oxide) on the action potential of papillary muscles of guinea pigs and the ATP-sensitive potassium channel current(IKATP) of single... -
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- Design of Mobile Emergency Telemedicine System Based on CDMA2000 1X-EVDO
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Jung SM, Yoo SK, Kim BS, Yun HY, Kim SR
- KMID: 2330201
- J Korean Soc Med Inform.
- 2003 Dec;9(4):401-406.
Using a high bandwidth cellular communication network is appropriate to implement a high-quality mobile emergency telemedicine system. In Korea, the commercial service of CDMA2000 1X-EVDO has been providing since 2002.... -
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- Enhancements of Mouse Hepatic Cytosol Enzyme Activities Involved in UDP-Glucuronic Acid Synthesis, Glutathione Reduction and Conjugation with Butylated Hydroxyanisole (BHA) and Its Structural Analogs
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Cha YN, Chung JH, Heine HS, Hong SS
- KMID: 692978
- Yonsei Med J.
- 1984 Dec;25(2):105-115.
- doi: 10.3349/ymj.1984.25.2.105
Activities of hepatic cytosol enzymes involved in UDP-g1ucuronic acid synthesis as well as in glutathione reduction and conjugation systems were determined following administrations of butylated hydroxyanisole (approximately 5 mmol/kg body... -
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- Is it Possible to Perform Chest Compression in Various Alternative Positions in a Confined Space?: A Manikin and Simulation Study
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Kim YM, Park SO, Lee KR, Hong DY, Baek KJ
- KMID: 2332782
- J Korean Soc Emerg Med.
- 2010 Aug;21(4):417-422.
PURPOSE: Standard chest compression is useful for cardiopulmonary resuscitation of victims but may be difficult to perform in a confined space if the victim is lying on his side. The... -
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- Galactosemia Detected by Neonatal Screening Test
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Park IS, Cho HJ, Lee DH, Song JH
- KMID: 2335722
- J Korean Pediatr Soc.
- 2003 May;46(5):440-446.
PURPOSE: The genetic disturbance of galactosemia is expressed as a cellular deficiency of either galactose-1-phosphate uridyltransferase(GALT) or galactokinase(GALK) or UDP galactose 4-epimerase(GALE). To find-out the pattern of galactosemia in Korea,... -
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