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An Association Study of the Signal Transducer and Activator of Transcription 6 Gene With Periodic Psychosis

Kawashige , Kanazawa T, Tsutsumi A, Kikuyama H, Uenishi H, Koh J, Yoneda H

  • KMID: 2315784
  • Psychiatry Investig.
  • 2008 Mar;5(1):41-44.
OBJECTIVE: Recent molecular and genetic investigations have suggested that the current nosology for major psychiatric disorders, based on the "two-entities-principal" is not accurate with respect to clinical observations; patient groups...
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Increases in iPS Transcription Factor (Oct4, Sox2, c-Myc, and Klf4) Gene Expression after Modified Electroconvulsive Therapy

Nishiguchi M, Kikuyama H, Kanazawa T, Tsutsumi A, Kaneko T, Uenishi H, Kawabata Y, Kawashige , Koh J, Yoneda H

OBJECTIVE: Electroconvulsive therapy (ECT) is a reasonable option for intractable depression or schizophrenia, but a mechanism of action has not been established. One credible hypothesis is related to neural plasticity....
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Genetic Polymorphisms in Dopamine- and Serotonin-Related Genes and Treatment Responses to Risperidone and Perospirone

Tsutsumi A, Kanazawa T, Kikuyama H, Okugawa G, Uenishi H, Miyamoto T, Matsumoto , Koh J, Shinosaki , Kishimoto , Yoneda H, Kinoshita

  • KMID: 2315841
  • Psychiatry Investig.
  • 2009 Sep;6(3):222-225.
We investigated the possible association between genetic polymorphisms in the dopamine receptor and serotonin transporter genes and the responses of schizophrenic patients treated with either risperidone or perospirone. The subjects...
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