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Statistical Analysis of Gene Expression in Innate Immune Responses: Dynamic Interactions between MicroRNA and Signaling Molecules

Piras V, Selvarajoo K, Fujikawa N, Choi S, Tomita M, Giuliani A, Tsuchiya M

  • KMID: 2166264
  • Genomics Inform.
  • 2007 Sep;5(3):107-112.
MicroRNAs (miRNAs) are known to negatively control protein-coding genes by binding to messenger RNA (mRNA) in the cytoplasm. In innate immunity, the role of miRNA gene silencing is largely unknown....
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Toll-like receptor signal transduction

Krishnan J, Selvarajoo K, Tsuchiya M, Lee G, Choi S

  • KMID: 756065
  • Exp Mol Med.
  • 2007 Aug;39(4):421-438.
Toll-like receptors (TLRs) are the archetypal pattern recognition receptors in sensing exogenous pathogens. Activation of TLRs is a first line of defense of the immune system, leading to the activation...
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