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Effects of tretinoin pretreatment on TCA chemical peel in guinea pig skin

Kim IH, Kim HK, Kye YC

This study was done to characterize the structural changes in the tretinoin pretreatment on trichloroacetic acid(TCA) chemical peel. In guinea pigs, the right halves pretreated with tretinoin and the left...
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Detection of Telomerase Activity in Psoriasis Lesional Skin and Correlaton with Ki-67 Expression and Suppression by Retinoic Acid

Jang HS, Oh CK, Jo JH, Kim YS, Kwon KS

Telomerase activity is usually detected in most tumor tissues but not in normal tissues. Recently, there is increasing evidence that telomerase activity is associated with cell proliferation without malignancy, whereas...
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Retinoic acid inhibits inducible nitric oxide synthase expression in 3T3-L1 adipocytes

Yang JY, Koo BS, Kang MK, Rho HW, Sohn HS, Jhee EC, Park JW

  • KMID: 755207
  • Exp Mol Med.
  • 2002 Nov;34(5):353-360.
The present study was undertaken to explore whether retinoids, which are known to have immunomodulatory actions, could attenuate tumor necrosis factor-alpha (TNF)-stimulated inducible nitric oxide synthase (iNOS) expression in 3T3-L1...
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All-Trans Retinoic Acid Has a Potential Therapeutic Role for Diabetic Nephropathy

Kim CS, Park JS, Ahn CW, Kim KR

PURPOSE: The aim of this study was to examine the effects of all-trans retinoic acid (ATRA) on diabetic nephropathy. MATERIALS AND METHODS: We measured amounts of urinary albumin excretion (UAE) after...
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Effects of retinoic acid on ischemic brain injury-induced eurogenesis

Jung DS, Baek SY, Park KH, Chung YI, Kim HJ, Kim CD, Cho MK, Han ME, Park KP, Kim BS, Kim JB, Oh SO

  • KMID: 1047081
  • Exp Mol Med.
  • 2007 Jun;39(3):304-315.
Neurogenesis can be induced by pathological conditions such as cerebral ischemia. However the molecular mechanisms or modulating reagents of the reactive neurogenesis after the cerebral ischemia are poorly characterized. Retinoic...
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p38 MAPK and ERK activation by 9-cis-retinoic acid induces chemokine receptors CCR1 and CCR2 expression in human monocytic THP-1 cells

Ko J, Yun CY, Lee JS, Kim JH, Kim IS

  • KMID: 1094653
  • Exp Mol Med.
  • 2007 Apr;39(2):129-138.
9-cis-retinoic acid (9CRA) plays an important role in the immune response; this includes cytokine production and cell migration. We have previously demonstrated that 9CRA increases expression of chemokine receptors CCR1...
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Real-time PCR analysis of the apoptosis related genes in ATRA treated APL t(15;17) patients

Savli H, Sirma S, Nagy B, Aktan M, Dincol G, Ozbek U

  • KMID: 1093619
  • Exp Mol Med.
  • 2003 Oct;35(5):454-459.
All-trans retinoic acid (ATRA) treatment of the acute promyelocytic leukemia (APL) have subsequently resulted in cell apoptosis, but the molecular mechanism of this effect remains elusive. In order to understand...
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