- The Transforming Growth Factor-beta1 Expression in Normal Laryngeal Mucosa, Laryngeal Dysplasia and Laryngeal Carcinoma
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Jin YW, Lee DY, Cha CI, Park SH, Hong NP, Ahn HY
- KMID: 2274572
- Korean J Otolaryngol-Head Neck Surg.
- 1999 Apr;42(4):478-482.
BACKGROUND AND OBJECTIVES: Transforming growth factor-beta1 (TGF-beta1) is a multifunctional regulator of cellular differentiation, motility and growth. Loss of sensitivity to the growth inhibitory effects by TGF-beta1 plays important roles... -
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- Inhibition of Cell Growth and Suppression of c-myc Gene Expression by Transforming Growth Factor-beta1 in Cervical Carcinoma Cell Lines
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Kim JW, Kim MR, Kim JH, Kim TE, Park TC, Lee HY, Kim SJ, Namkoong S
- KMID: 2260724
- Korean J Obstet Gynecol.
- 1997 Jan;40(1):154-160.
Transforming growth factor-beta1(TGF-beta1) is known to be a potent growth inhibitor for many cell types, including most epithelial cells. In skin keratinocytes, TGF-beta1 has been shown to inhibit growth and... -
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- Differential Expression of TGF-beta Isoforms in Human Kerationocytes by Narrow Band UVB
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Jung MC, Shin MK, Hong KK, Jeong KH, Kim NI
- KMID: 2156375
- Ann Dermatol.
- 2008 Sep;20(3):113-119.
- doi: 10.5021/ad.2008.20.3.113
BACKGROUND: Transforming growth factor-beta (TGF-beta), a multifunctional growth factor, has three isoforms: TGF-beta1, TGF-beta2, and TGF-beta3. Different isoforms of TGF-beta are associated with different proliferation and differentiation states of the... -
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- Changes of Interleukin-12 and Transforming Growth Factor Beta 1 before and after Antipsychotic Treatments in Schizophrenic Patients
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Kim SJ, Lee BH, Kim YK
- KMID: 2299956
- Korean J Biol Psychiatry.
- 2005 Nov;12(2):143-150.
BACKGROUND: Several reports have suggested that cytokine alterations could be related to the pathophysiology of schizophrenia. In this study, we measured plasma level of interleukin-12(IL-12), a pro-inflammatory T helper 1(Th1)... -
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- Significant fibrosis after radiation therapy in a patient with Marfan syndrome
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Suarez EM, Knackstedt RJ, Jenrette J
- KMID: 2316736
- Radiat Oncol J.
- 2014 Sep;32(3):208-212.
- doi: 10.3857/roj.2014.32.3.208
Marfan syndrome is one of the collagen vascular diseases that theoretically predisposes patients to excessive radiation-induced fibrosis yet there is minimal published literature regarding this clinical scenario. We present a... -
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- Expression of Transforming Growth Factor -beta1, -beta2 in Human Endometrium of The Uterine Adenocarcinoma
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Moon YJ, Shin JS
- KMID: 2083751
- Korean J Gynecol Oncol Colposc.
- 2000 Mar;11(1):76-82.
OBJECTIVE: To determine the differences of expression of Transforming Growth Factor (TGF)-beta1 and TGF-beta2 in the human proliferative, secretory, menopausal endometrium, and in hyperplasia and adenocarcinoma of the endometrium. MATERIALS... -
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- The Effect of Transforming Growth Factor-beta and Mannose-6-Phosphate on the Proliferation of Subconjunctival Fibroblast of Rabbit
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Lee YG, Chang JH, Kay ED, Hong YJ
- KMID: 2108329
- J Korean Ophthalmol Soc.
- 1997 Dec;38(12):2129-2135.
The main cause of failure in glaucoma filtering surgery is obstruction of aqueous outflow due to subconjunctival fibrosis. Transforming growth factor-beta(TGF-beta) is known to be a growth factor for subconjunctival... -
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- Effect of Transforming Growth Factor-beta1 on Expressions of Epidermal Growth Factor and Transforming Growth Factor-alpha in DU145 Androgen-Independent Prostate Cancer Cells
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Shin KY, Kong G, Choi HS, Lee JJ, Lee TY
- KMID: 2292443
- Korean J Urol.
- 2001 Jan;42(1):40-46.
PURPOSE: This study was designed to identify the possible mechanism of insensitivity of DU145 prostate cancer cells to the transforming growth factor (TGF)-beta1-mediated growth inhibition. MATERIALS AND METHODS: DU145 cells were... -
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- Regulation of the Levels of Trabecular Matrix Metalloproteinase and Inhibitor by Transforming Growth Factor-beta1
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Seong GJ
- KMID: 2336611
- J Korean Ophthalmol Soc.
- 1997 Mar;38(3):406-412.
The present study investigates the role of TGF-beta1 as one of possible etiologic factors of glaucoma by studying the effect of TGF-beta1 on the secretion of matrix metalloproteinase and tissue... -
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- Expression of Transforming Growth Factor-beta1 and Its Effects on the Extracellular Matrix Formation and Angiogenesis in Gastric Carcinoma
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Choi YH, Park YE
- KMID: 1725431
- Korean J Pathol.
- 1998 Sep;32(9):647-654.
Malignant cells in culture express elevated levels of transforming growth factor-beta1 (TGF-beta1) mRNA and secrete an abundant amount of the TGF-beta1 protein. An attempt was made to define the role... -
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- Effects of TGF-beta1 Ribbon Antisense on CCl4-induced Liver Fibrosis
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Doh KO
- KMID: 2071639
- Korean J Physiol Pharmacol.
- 2008 Feb;12(1):1-6.
- doi: 10.4196/kjpp.2008.12.1.1
Ribbon-type antisense oligonucleotide to TGF-beta1(TGF-beta1 RiAS) was designed and tested to prevent or resolve the fibrotic changes induced by CCl4 injection. When Hepa1c1c7 cells were transfected with TGF-beta1 RiAS, the... -
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- Expression of TGF-beta isoforms in the Human Fetal Hepatic Erythropoiesis
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Kee SW, Kim YW, Kim SS, Kim KY, Lee WB
- KMID: 2071840
- Korean J Phys Anthropol.
- 1999 Jun;12(1):23-32.
The expression patterns of transforming growth factor-betas (TGF-betas) were studied immunohis-tochemically in hepatic erythropoietic cells and hepatocytes of 3 human fetal livers from 21 to 26 gestation weeks. The results... -
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- Changes of TGF-beta1 in Rabbit Vitreous after Cryotherapy
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Lee SH, Chang MH, Lee JH
- KMID: 2205569
- J Korean Ophthalmol Soc.
- 1999 Sep;40(9):2538-2543.
The exact mechanism of regression of retinal neovasculari- zation was not proven yet, although panretinal photocoagu- lation and cryotherapy have been used in treatment of retinal neovascularization. Recent studies show... -
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- Expression of TGF-alpha, beta1, beta2 in Pterygial Mast cell
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Kim TH, Seo SW, Song JK
- KMID: 2206119
- J Korean Ophthalmol Soc.
- 2002 Jul;43(7):1261-1268.
PURPOSE: To evaluate whether TGF-alpha, beta1, beta2 are expressed in pterygial mast cell and the difference between each growth factor exists. METHODS: We prepared 10 pieces each of excised normal conjunctiva,... -
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- Expression of TGF-beta1 and TGF-betatype II Receptor in Chemically Induced Hepatocarcinogenesis of the Rat
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Park DY, Park KW, Suh KS
- KMID: 1921707
- Korean J Pathol.
- 2003 Apr;37(2):121-128.
BACKGROUND: Transforming growth factor (TGF)-beta1 inhibits hepatocyte proliferation by inducing apoptosis. Expression of TGF-beta1 is tightly associated with the TGF-betatype II receptor (TGR2) expression level, and has been regarded as... -
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- The Effects of TGF-beta1 & TGF-beta2 on the Proliferation of the Lumbar Facet Joint Capsule in Tissue Culture
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Lee KY, Yoo YH, Cho KW
- KMID: 2097644
- J Korean Soc Spine Surg.
- 1998 May;5(1):25-32.
STUDY DESIGN: This study was undertaken to document the effect of TGF-beta 1 and TGF-beta2 on the proliferation of lumbar facet joint capsule. OBJECTIVES: To study the effect of TGF-beta1 and... -
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- Expression of Transforming Growth Factor-beta1 , beta2 by Immunohistochemical Staining method: In Human Endometrium through the Menstrual Cycle
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Hwang JH, Hwang YY, Jang SJ
- KMID: 2075301
- Korean J Obstet Gynecol.
- 1997 Sep;40(9):1829-1834.
OBJECTIVES: The purpose of this study was to determine the differences of expression of TGF-betaS(TGF-beta1 and TGF-beta2) in the human proliferative endometrium, secretory endometrium, and the decidua during early pregnancy.... -
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- The Metabolic and Morphological Effects of Transforming Growth Factor (TGF)-beta1 in Bovine Retinal Pigment Epithelial Cells
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Lee JS, Lee JE, Park HJ, Oum BS
- KMID: 2206654
- J Korean Ophthalmol Soc.
- 2003 Aug;44(8):1895-1902.
PURPOSE: To evaluate the effects of transforming growth factor (TGF)-beta1 on the cellular metabolic activity and morphological changes on retinal pigment epithelial cells that influence the development of proliferative vitreoretinopathy.... -
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- Transforming Growth Factor-beta1 Promoter Polymorphism in Childhood Asthma
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Park JY, Song TW, Kim KW, Kim ES, Sohn MH, Kim KE
- KMID: 2314512
- Pediatr Allergy Respir Dis.
- 2007 Sep;17(3):226-233.
PURPOSE: The -509C/T polymorphism of the transforming growth factor (TGF)-beta1 gene has been associated with asthma and atopy. We evaluate whether TGF-beta1 promoter polymorphism (-509C/T) is associated with the asthma... -
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- Clinical Significance of Plasma TGF-beta1 in Patients with Colorectal Cancer
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Bae SY, Lim BJ, Choi SK, Shin H, Lim CK, Lee GS, Hur YS, Lee KY, Kim SJ, Ahn SI, Hong KC, Shin SH, Woo ZH
- KMID: 1647236
- Korean J Gastroenterol.
- 2002 Nov;40(5):313-319.
BACKGROUND/AIMS: Transforming growth factor-beta1 (TGF-beta1) is a polypeptide with wide-ranging effects including cellular proliferation, differentiation, immunosuppression, apoptosis, and matrix remodeling. It has been reported that TGF-beta1 is closely associated with... -
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