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Toll-like receptor 9 dependent activation of MAPK and NF-kB is required for the CpG ODN-induced matrix metalloproteinase-9 expression

Lim EJ, Lee SH, Lee JG, Kim JR, Yun SS, Baek SH, Lee C

  • KMID: 1094665
  • Exp Mol Med.
  • 2007 Apr;39(2):239-245.
Unmethylated CpG oligodeoxynucleotides (CpG ODNs) activate immune cells to produce immune mediators. This study demonstrates that in murine macrophage RAW 264.7 cells, CpG ODN-mediated matrix metalloproteinase-9 (MMP-9) expression is regulated...
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