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Association of Toll-Like Receptor Gene with Crohn's Disease in Koreans

Ye BD, Yang SK, Song K, Yang DH, Yoon SM, Kim KJ, Byeon JS, Myung SJ, Kim JH

BACKGROUND/AIMS: Toll-like receptors (TLRs) serve as pattern recognition receptors that recognize specific molecular patterns of pathogens and can mediate the production of proinflammatory cytokines. Recently, TLRs have been identified as...
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Association between Toll-Like Receptor 9-1237T/C Polymorphism and the Susceptibility of Inflammatory Bowel Diseases: A Meta-Analysis

Shang J, Wang X, Wang W, Pan H, Liu S, Li L, Chen L, Xia B

PURPOSE: The -1237T/C polymorphism of the Toll-like receptor 9 (TLR9) gene has been implicated in the susceptibility of inflammatory bowel diseases (IBDs), but the results remain conflicting. We further investigated...
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