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Matrix metalloproteinases in human gliomas: activation of matrix metalloproteinase-2 (MMP-2) may be correlated with membrane-type-1 matrix metalloproteinase (MT1-MMP) expression

Hur JH, Park MJ, Park IC, Yi DH, Rhee CH, Hong SI, Lee SH

To evaluate possible roles of matrix metalloproteinase (MMP)-1, -2, tissue inhibitor of metalloproteinase (TIMP)-1, -2 and membrane-type-1 matrix metalloproteinase (MT1-MMP) in invasion of human gliomas, expressions of these proteins were...
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Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma

Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ

Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial...
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Expression of Tissue Inhibitors of Metalloproteinases (TIMPs) in Hepatocellular Carcinoma

Joo YE, Seo YH, Lee WS, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

  • KMID: 759515
  • Korean J Intern Med.
  • 2000 Dec;15(3):171-178.
BACKGROUND: Matrix metalloproteinases (MMPs) have been implicated in the remodelling of extracellular matrix (ECM), including basement membrane. ECM remodelling is associated with pathological processes, including hepatic fibrosis, tumor invasion and...
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The Pattern of Differentially Expressed Genes in Biliary Atresia

Choe BH, Kim KM, Kwon S, Lee KS, Koo JH, Lee HM, Kim MK, Kim JC

Biliary atresia is a progressive obliterative cholangiopathy, but the etiology of this disorder remains uncertain. Identifying genes specifically expressed in biliary atresia and analyzing the pattern of expression may lead...
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