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Role of tissue inhibitors of metalloproteinases (TIMPs) in colorectal carcinoma

Joo YE, Seo KS, Kim J, Kim HS, Rew JS, Park CS, Kim SJ

Increased production of matrix metalloproteinases (MMPs) has been associated with increases in invasive and metastatic potential in many types of human carcinoma. Tissue inhibitors of metalloproteinase (TIMP)-1 inhibits most interstitial...
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Expression of Tissue Inhibitors of Metalloproteinases (TIMPs) in Hepatocellular Carcinoma

Joo YE, Seo YH, Lee WS, Kim HS, Choi SK, Rew JS, Park CS, Kim SJ

  • KMID: 759515
  • Korean J Intern Med.
  • 2000 Dec;15(3):171-178.
BACKGROUND: Matrix metalloproteinases (MMPs) have been implicated in the remodelling of extracellular matrix (ECM), including basement membrane. ECM remodelling is associated with pathological processes, including hepatic fibrosis, tumor invasion and...
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