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Delayed Cancer Diagnosis in Thyroid Nodules Initially Treated as Benign With Radiofrequency Ablation: Ultrasound Characteristics and Predictors for Cancer

Kim MK, Shin JH, Hahn SY, Kim H

Objective: Regrowth after radiofrequency ablation (RFA) of symptomatic large thyroid nodules, initially treated as benign, sometimes turns out to be malignancies. This study aimed to assess the ultrasound (US) characteristics...
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A Case of Thyroid Abscess Following Ethanol Ablation for Benign Thyroid Nodule

Cho H, Ahn D, Kwak JH, Lee GJ

Recently, non-surgical and minimally invasive treatments, including ethanol ablation (EA) and radiofrequency ablation (RFA), have been commonly used as primary treatments for benign thyroid nodules. While these techniques have been...
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Reevaluating diagnostic categories and associated malignancy risks in thyroid core needle biopsy

Jung CK

As the application of core needle biopsy (CNB) in evaluating thyroid nodules rises in clinical practice, the 2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules have officially...
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Radiofrequency ablation of benign thyroid nodules: the value of anterolateral hydrodissection

Jeong SY, Baek JH, Chung SR, Choi YJ, Chung KW, Kim TY, Lee JH

Purpose: This study aimed to evaluate the technical feasibility, efficacy, and safety of anterolateral hydrodissection (ALHD) in radiofrequency ablation (RFA) for benign thyroid nodules. Methods: Between November 2019 and April 2020,...
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Sclerotherapy with a Viscum Album Extract for the Two Patients with Cystic Thyroid Nodule

Lee JH, Lee SW, Park KN

We report two cases of successful treatment of thyroid cystic nodules using Viscum Album extract as a sclerotherapy material. Both cases showed volume reduction of more than 50%, and it...
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Artificial Intelligence Computer-Assisted Diagnosis for Thyroid Nodules: Comparison of Diagnostic Performance Using Original and Mobile Ultrasonography Images

Cho S, Lee E, Lee H, Lee HS, Yoon JH, Park VY, Rho M, Yoon J, Kwak JY

Background and Objectives: This study investigated whether an artificial intelligence computer-assisted diagnosis (AI-CAD) software recently developed in our institution named the Severance Artificial intelligence program (SERA) could show similar diagnostic...
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2023 Korean Thyroid Association Management Guidelines for Patients with Thyroid Nodules

Park YJ, Lee EK, Song YS, Kang SH, Koo BS, Kim SW, Na DG, Baek SK, Oh SW, Lee MK, Lee SW, Lee YA, Lee YS, Lee JY, Lim DJ, Joo L, Jung YS, Jung CK, Cho YY, Chung YJ, Kim WB, Yi KH, Kang HC, Park DJ

Thyroid nodules are a prevalent condition that can be detected through palpation or ultrasound. However, a small fraction of these nodules can be cancerous, and even benign nodules can cause...
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Subcategorization of intermediate suspicion thyroid nodules based on suspicious ultrasonographic findings

Kim H, Shin JH, Kim KE, Kim MK, Oh J, Hahn SY

Purpose: This study compared the malignancy risk of intermediate suspicion thyroid nodules according to the presence of suspicious ultrasonographic (US) findings. Methods: From January 2014 to December 2014, 299 consecutive intermediate...
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Risk of thyroid cancer in a lung cancer screening population of the National Lung Screening Trial according to the presence of incidental thyroid nodules detected on low-dose chest CT

Seo H, Jin KN, Park JS, Kang KM, Lee EK, Lee JY, Yoo RE, Park YJ, Kim Jh

Purpose: This study evaluated thyroid cancer risk in a lung cancer screening population according to the presence of an incidental thyroid nodule (ITN) detected on low-dose chest computed tomography (LDCT). Methods:...
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Combined fine-needle aspiration with core needle biopsy for assessing thyroid nodules: a more valuable diagnostic method?

Chen Z, Wang Jj, Guo Dm, Zhai Yx, Dai Zz, Su Hh

Purpose: This study aimed to evaluate the diagnostic value of combined fine-needle aspiration (FNA) with core needle biopsy (CNB) in thyroid nodules. Methods: FNA and CNB were performed simultaneously on 703...
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Diagnostic Performance of Ultrasound-Based Risk Stratification Systems for Thyroid Nodules: A Systematic Review and Meta-Analysis

Joo L, Lee MK, Lee JY, Ha EJ, Na DG

Background: This study investigated the diagnostic performance of biopsy criteria in four society ultrasonography risk stratification systems (RSSs) for thyroid nodules, including the 2021 Korean (K)-Thyroid Imaging Reporting and Data...
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A Comprehensive Assessment of the Harms of Fine-Needle Aspiration Biopsy for Thyroid Nodules: A Systematic Review

Park JY, Choi W, Hong AR, Yoon JH, Kim HK, Kang HC

Background: There have concerns related with the potential harms of fine-needle aspiration biopsy (FNAB). We aimed to summarize the clinical complications and evaluate the safety of FNAB. Methods: Studies related with...
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Clinical Application of the 2021 Korean Thyroid Imaging Reporting and Data System (K-TIRADS)

Na DG

In patients with thyroid nodules, ultrasonography (US) has been established as a primary diagnostic imaging method and is essential for treatment decision. The Korean Thyroid Imaging Reporting and Data System...
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Follow-up of benign thyroid nodules confirmed by ultrasound-guided core needle biopsy after inconclusive cytology on fine-needle aspiration biopsy

Hwang YJ, Koo HR, Park JS

Purpose: The goal of this study was to follow benign thyroid nodules confirmed by ultrasound (US)-guided core needle biopsy (CNB) after inconclusive cytology on fine-needle aspiration (FNA) biopsy. Methods: Sixty-two thyroid...
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Orientation of the ultrasound probe to identify the taller-than-wide sign of thyroid malignancy: a registry-based study with the Thyroid Imaging Network of Korea

Hong MJ, Lee YH, Kim Jh, Na DG, You SH, Shin JE, Kim SK, Yang KS, Korean Society of Thyroid Radiology

Purpose: Although the taller-than-wide (TTW) sign has been regarded as one of the most specific ultrasound (US) features of thyroid malignancy, uncertainty still exists regarding the US probe’s orientation when...
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Update from the 2022 World Health Organization Classification of Thyroid Tumors: A Standardized Diagnostic Approach

Jung CK, Bychkov A, Kakudo K

The fifth edition of the World Health Organization (WHO) histologic classification of thyroid neoplasms released in 2022 includes newly recognized tumor types, subtypes, and a grading system. Follicular cell-derived neoplasms...
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2021 Korean Thyroid Imaging Reporting and Data System (2021-K-TIRADS) and Imaging-Based Management of Thyroid Nodules: Korean Society of Thyroid Radiology Consensus Statement and Recommendations

Jung SL

The rate of detection of thyroid nodules and carcinomas has increased with the widespread use of ultrasonography (US), which is the primary imaging modality for the detection and risk stratification...
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Long-term follow-up of the radiofrequency ablation of benign thyroid nodules: the value of additional treatment

Kim HJ, Baek JH, Cho W, Sim JS

Purpose: This study aimed to evaluate the efficacy of additional radiofrequency ablation (RFA) treatment for benign thyroid nodules. Methods: Electronic medical records at a single institution from September 2008 to August...
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Malignancy risk of thyroid nodules with minimal cystic changes: a multicenter retrospective study

Lee YJ, Kim JY, Na DG, Kim Jh, Oh M, Kim DB, Yoon RG, Kim SK, Bak S

Purpose: The aim of this multicenter study was to investigate the malignancy risk of minimally cystic thyroid nodules (MCTNs) using cyto-histopathologic diagnoses as the reference standard. Methods: From June 2015 to...
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Benign Thyroid Enlargement Across Racial and Ethnic Groups

Young LC, Ow TJ, Lin J, Schiff BA, Smith RV, Mehta V

Purpose: The objective of this study is to determine if there is a significant correlation between race/ethnicity and total thyroid volume among patients with benign thyroid disease. Our hypothesis is that...
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