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Colchicine-derived compound CT20126 promotes skin allograft survival by regulating the balance of Th1 and Th2 cytokine production

Lee SJ, Namkoong S, Ha KS, Nam WD, Kwon YG, Lee H, Yoon EY, Chang DJ, Kim SO, Kim YM

  • KMID: 1094664
  • Exp Mol Med.
  • 2007 Apr;39(2):230-238.
Colchicine has been shown to regulate the expression of inflammatory gene, but this compound possesses much weaker anti-inflammatory activity. In this study, we synthesized a new colchicine derivative CT20126 and...
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