- Increased levels of multiple forms of dihydrofolate reductase in peripheral blood leucocytes of cancer patients receiving haematopoietic colony-stimulating factors: interim analysis
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Iqbal MP, Burney IA, Sultana F, Mehboobali N, Siddiqui T
- KMID: 1109307
- Exp Mol Med.
- 2000 Jun;32(2):84-87.
The precise mechanism whereby granulocytes proliferate when haematopoietic colony stimulating factors (CSFs) are used in neutropenic cancer patients is poorly understood. The purpose of this study was to investigate whether... -
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- Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates
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Baek EJ, Nam HW
- KMID: 662563
- Korean J Parasitol.
- 1998 Sep;36(3):191-198.
- doi: 10.3347/kjp.1998.36.3.191
The responses to antifolates of Toxoplasma gondii were investigated by measuring the dihydrofolate reductase (DHFR) activity, quantity of DHFR mRNA, and single-strand conformational polymorphism (SSCP) pattern. Pyrimethamine (PYM) and methotrexate... -
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