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Benefits and risks of therapeutic alternatives for macrolide resistant Mycoplasma pneumoniae pneumonia in children

Yang HJ

Although Mycoplasma pneumoniae pneumonia (MPP) has been generally susceptible to macrolides, the emergence of macrolide-resistant MPP (MRMP) has made its treatment challenging. MRMP rapidly spread after the 2000s, especially in...
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Pharmacological treatment options for acne

Park KY

Acne vulgaris is a very common condition affecting up of about 80% to 90% of adolescents. The patients with acne have been shown to be adversely impacted by the effect...
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Mounting resistance of uropathogens to antimicrobial agents: A retrospective study in patients with chronic bacterial prostatitis relapse

Stamatiou , Pierris N

PURPOSE: Despite recent progress in the management of chronic bacterial prostatitis (CBP), many cases relapse. Increased drug resistance patterns of responsible bacteria have been proposed as the most probable causative...
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Mechanism of resistance acquisition and treatment of macrolide-resistant Mycoplasma pneumoniae pneumonia in children

Yang HJ, Song DJ, Shim JY

Mycoplasma pneumoniae pneumonia (MPP) is one of the most common forms of community-acquired pneumonia in children and adolescents. Outbreaks of MPP occur in 3- to 7-year cycles worldwide; recent epidemics...
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Antibiotic Resistance and Novel Antibiotics for the Treatment of Urinary Tract Infections

Wagenlehner F

Surveillance data on antibiotic resistance need to be considered with respect to the origin of isolates, types of surveillance studies, and types of types of registered infections. Antibiotic resistance in...
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Increasing Incidence of High-Level Tetracycline-Resistant Neisseria gonorrhoeae due to Clonal Spread and Foreign Import

Lee H, Kim H, Kim HJ, Suh YH, Yong D, Jeong SH, Lee K, Chong Y

PURPOSE: The detection of high-level tetracycline-resistant strains of Neisseria gonorrhoeae (TRNG) can make important epidemiological contributions that are relevant to controlling infections from this pathogen. In this study, we aimed...
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Prevalence and Antimicrobial Susceptibility of Genital Mycoplasmataceae in Korean Women: Correlation between Phenotypic Test and Resistance Genes

Chang J, Yu JK, Song C, Park IY, Park YJ

BACKGROUND: While 7.6% of cultured genital Mycoplasmataceae was identified as Ureaplasma urealyticum, most of them were Ureaplasma parvum (80.3%). This is the first study differentiating between these two species. We...
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Triple Primary Origin Tumor: A Case Report

Jung YS, Kim SH, Ha SK, Kim SD, Lim DJ

Generally, among the extradural spinal tumors, metastatic spinal tumor is much more common than primary spinal tumors. Thus, in the case of a spinal tumor patient with cancer history (such...
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Tigecycline Treatment for Infections Caused by Multidrug-Resistant Pathogens

Lee MJ, Seo AY, Bae SS, Jeong DH, Yoon KH, Hwang BS, Kang SH, Oh DM, Kwon KT, Lee SW, Song DY

  • KMID: 2320054
  • Yeungnam Univ J Med.
  • 2011 Dec;28(2):133-144.
BACKGROUND: Tigecycline (TIG), a new broad-spectrum glycylcycline with anti-multidrug-resistant-(MDR)-pathogen activity, was launched in March 2009 in South Korea, but there are insufficient clinical studies on its use in the country....
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Pharmacologic Treatment of Acne

Suh DH

Acne is one of the most common skin diseases. It usually occurs during adolescence, but can persist into middle age. The most deleterious form can result in permanent scarring on...
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A Case of Generalized Hyperpigmentation Caused by Antituberculosis Drugs

Kim BS, Won TH, Seo PS, Park SD

  • KMID: 2248027
  • Korean J Dermatol.
  • 2008 Nov;46(11):1513-1516.
Hyperpigmentation caused by medication or toxic agents accounts for 10~20% of all the cases of acquired hyperpigmentations. Nonsteroidal anti-inflammatory drugs, antimalarials, amiodarone, cytotoxic drugs, tetracyclines, heavy metals and psychotropic drugs...
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A Case of Fixed Drug Eruption Caused by Acetaminophen in a Child

Hong KB, Jin YM, Kang J, Im IJ, Roh EJ, Son JS, Chung EH

  • KMID: 2314522
  • Pediatr Allergy Respir Dis.
  • 2007 Sep;17(3):314-319.
Fixed drug eruption (FDE) is an eruption, which recurs at the same site or sites on each administration of the causative drug, and heals with residual hyperpigmentation. FDE is caused...
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Effect of Antibiotics on the Survival of Human Hepatocellular Carcinoma Cells under Hypoxic Conditions

Lee YT, Han MJ, Lim SH, Park SH, Suh HS, Park JB, Kim YI, Lee J

  • KMID: 2145084
  • J Korean Surg Soc.
  • 2006 Jul;71(1):31-38.
PURPOSE: Antibiotics that kill or suppress the growth of bacteria also affect tumors directly or indirectly. The authors aimed to show whether some antibiotics can improve cancer cell survival under...
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The Trend of Antibiotic Production in Korea during 1981~2003

Kim YJ, Lee SH, Kang YN, Kim WC, Kim SI, Wie SH, Kim YR, Kang MW

  • KMID: 2054307
  • Infect Chemother.
  • 2005 Oct;37(5):271-279.
BACKGROUND: It is difficult to know the actual situation of antibiotic usage in Korea. We investigated the trend of antibiotic production every five years from 1981 to 2003 by using...
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Antimicrobial Susceptibilities of Viridans Streptococci Isolated from Blood Cultures during Recent Period

Uh Y, Hwang GY, Jang IH, Yoon KJ, Kim HY

  • KMID: 2325364
  • J Lab Med Qual Assur.
  • 2002 Dec;24(2):225-230.
BACKGROUND: Viridans group streptococci (VGS) are being increasingly reported as pathogens causing septicemia in neutropenic and other immunocompromised patients since 1980s. In the past, VGS were nearly uniformly susceptible to...
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Antimicrobial Activities of Arbekacin against Clinical Isolates of Staphylococcus aureus and Coagulase-Negative Staphylococcus Species

Wie SH, Kang JH, Huh DH, Lee DG, Kim SI, Kim YR, Choi JH, Kim JH, Yoo JH, Hur JK, Shin WS, Kang MW

  • KMID: 2248680
  • Korean J Infect Dis.
  • 2001 Aug;33(4):254-260.
BACKGROUND: Most strains of methicillin-resistant Staphylococcus aureus (MRSA) now exhibit high-level resistance to various antibiotics, such as beta-lactam antibiotics, aminoglycosides, macrolides, tetracyclines and quinolones. Recent reports describing the therapeutic failure...
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The Trend of Antibiotics Usage in Korea during 1981-1998

Kim SI, Park JM, Wie SH, Kim YR, Kang MW

  • KMID: 2147909
  • Korean J Infect Dis.
  • 2000 Dec;32(6):439-447.
BACKGROUND: With the time course, the cost and the amounts of produced antibiotics are increasing but it is difficult to get the exact data and there were limitations to know...
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A Case of Fixed Drug Eruption Due to Acetaminophen

Min EJ, Lim DH, Kim JH, Choi SW, Son BK

  • KMID: 2207508
  • J Korean Pediatr Soc.
  • 2000 Aug;43(8):1149-1152.
Fixed drug eruption normally presents as single or multiple sharply demarcated erythematous lesions that recur at the same location upon re-exposure to the offending agent. When the acute inflammation subsides, it often...
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Two cases of Creosote Induced Gastric Ulcer

Kim KY, Park JO, Shin SM

  • KMID: 2275122
  • Korean J Pediatr Gastroenterol Nutr.
  • 2000 Mar;3(1):84-88.
Secondary peptic ulceration and gastritis have been known to be associated with stress, exogenous agents, drugs or infection. Salicylate (aspirin) ingestion has been known to be associated with increased incidence...
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Fixed Drug Eruption Caused by Piroxicam

Yoon SP, Lee IH, Lee SH, Kim BS, Yoo JH, Lee SC

  • KMID: 2086041
  • Korean J Dermatol.
  • 1998 Feb;36(1):186-190.
A fixed drug eruption is a cutaneous reaction caused by various drugs, which include phenazone derivatives, barbiturates, sulfonamides, tetracyclines and phenolphthaleins. An eruption caused by piroxicam is very rare and...
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