- Teratogenicity of Antiepileptic Drugs
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Güveli BT, Rosti RÃ, GüzeltaÅŸ A, Tuna EB, Ataklı D, Sencer S, Yekeler E, Kayserili , Dirican A, Bebek N, Baykan B, GökyiÄŸit A, Gürses C
- KMID: 2367658
- Clin Psychopharmacol Neurosci.
- 2017 Feb;15(1):19-27.
- doi: 10.9758/cpn.2017.15.1.19
OBJECTIVE: Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is... -
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- Comparison of teratogenecity induced by nano- and micro-sized particles of zinc oxide in cultured mouse embryos
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Jung AY, Jung KY, Lin C, Yon JM, Lee JG, Lee BJ, Yun YW, Nam SY
- KMID: 1807802
- Korean J Vet Res.
- 2015 Jun;55(2):133-139.
- doi: 10.14405/kjvr.2015.55.2.133
The increasing uses of zinc oxide nanoparticles (nZnO) in industrial and personal care products raise possible danger of using nZnO in human. To determine whether ZnO induces size-dependent anomalies during... -
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- The Effect of X-irradiation on the Developing Incisor Tooth of the Rat
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Lee JH, Han SR, Kim SI, Cho KJ, Cho MJ, Kim WS
- KMID: 1609550
- Korean J Phys Anthropol.
- 2004 Dec;17(4):265-279.
In the development of tooth, the first sign is the localized thickening of oral ectoderm to form the tooth bud, and then through the dialogue between the bud and underlying... -
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- Optimal Drug Therapy During Pregnancy and Lactation
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Lim YC
- KMID: 2275001
- Chonnam Med J.
- 2001 Jun;37(2):85-97.
Although there are various risks of adverse drug reactions like teratogenesis, etc. in treating specific diseases during pregnancy and lactation, physicians have many difficulties to execute the optimal drug therapy... -
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- Radiation -induced Congenital Anomalies in the Rat Fetuses
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Lee WJ, Han SR, Jeong O, Kim SI, Cho MJ, Kim WS
- KMID: 1917175
- Korean J Phys Anthropol.
- 2001 Jun;14(2):159-168.
X -ray irradiation induces various congenital anomalies in the human fetuses and experimental animals. The action mechanism of teratogenesis, however, still not known completely. Furthermore, the dynamics of teratogenesis according... -
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- Neural Tube Defect of Chick Embryos by Needle Puncture and Albumen Removal
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Chung YN, Kim DH, Min KS, Lee MS
- KMID: 2188507
- J Korean Neurosurg Soc.
- 1999 Oct;28(10):1418-1428.
OBJECTIVE: The animal research of embryonic teratogenesis is widely performed and the neural tube defects are also studied through various animal models. Particularly, the experimental research on chick embryos is... -
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- Pathology of Cardiac Anomalies and Systemic Edema in the Murine Fetus with Trisomy 16
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Han YM, Yoo JH, Choi JY, Seo JW
- KMID: 2093694
- Korean Circ J.
- 1999 Jun;29(6):612-624.
- doi: 10.4070/kcj.1999.29.6.612
BACKGROUND: Trisomy 16 in mice is considered to be an animal model for Down's syndrome in human. We studied the morphologic characteristics of the heart and the edema, and their... -
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- Developmental mRNA Expression of Cellular Retinoic Acid Binding Protein l and l in Rat
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Yoo Y, Kim HS, Son CS, Tockgo YC, Jeon YH
- KMID: 2335334
- J Korean Pediatr Soc.
- 1998 Feb;41(2):154-162.
PURPOSE: Retinoic acid (RA) is well known as a potent teratogenic agent in both deficiency and excess. Cellular retinoic acid binding proteins (CRABPs) are involved in RA. We carried this... -
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- Analysis of FUDR --induced Congenital Anomalies in the Rat
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Yang EJ, Choi SP, Cho KJ, Kim SI, Kwon OY, Lee YH, Kim WS
- KMID: 2283034
- Korean J Phys Anthropol.
- 1997 Dec;10(2):191-198.
For the study on the teratogenic effects and its mechanism of FUDR on the developing rat fetuses, Sprague -Dawley rats as experimental animal and 5 -fluoro -2 '-deoxyuridine (Sigma chemicals)... -
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- The Effects of Retinoic Acid on Gastrulation of Hatched Mouse Embroyos
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Kang BM, Cheon YP, Kim NY, Kim CH, Chang YS, Mok JE
- KMID: 2271639
- Korean J Obstet Gynecol.
- 1997 Mar;40(3):518-523.
Retinoic acid(RA), formed in vivo by oxidation of retinol, is known as morphogenic signal. RA plays an active role in normal embryonic development at physiological concentration, but excess RA can... -
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- Diastematomyelia associated with clubfoot: A Case Report
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Kim YM, Han MS, Han SH
- KMID: 2461278
- J Korean Orthop Assoc.
- 1976 Sep;11(3):380-382.
- doi: 10.4055/jkoa.1976.11.3.380
Diastematomyelia, a form of spinal dysraphism, is characterized by a division of the spinal cord or canda equina resulting the form a bony or cartilaginous spur which transfixes the neural... -
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