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Telomere Length Changes in Colorectal Cancers and Polyps

Kim HR, Kim YJ, Kim HJ, Kim SK, Lee JH

Telomere Length Changes in Colorectal Cancers and Polyps Telomere shortening and telomerase activation occur frequently in cases of colorectal carcinoma. In this study, we correlated the clinicopathological parameters with the...
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A Case of 9.7 Mb Terminal Xp Deletion Including OA1 Locus Associated with Contiguous Gene Syndrome

Cho EH, Kim SY, Kim JK

Terminal or interstitial deletions of Xp (Xp22.2-->Xpter) in males have been recognized as a cause of contiguous gene syndromes showing variable association of apparently unrelated clinical manifestations such as Leri-Weill...
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Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence

Ju YJ, Lee KH, Park JE, Yi YS, Yun MY, Ham YH, Kim TJ, Choi HM, Han GJ, Lee JH, Lee J, Han JS, Lee KM, Park GH

  • KMID: 1115947
  • Exp Mol Med.
  • 2006 Dec;38(6):686-693.
The gradual loss of telomeric DNA can contribute to replicative senescence and thus, having longer telomeric DNA is generally considered to provide a longer lifespan. Maintenance and stabilization of telomeric...
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Molecular Mechanisms of Hepatitis B Virus-associated Hepatocellular Carcinoma

Park NH, Chung YH

Hepatocellular carcinoma (HCC) is one of the most common malignant diseases in the world. The hepatitis B virus (HBV) replicates non-cytopathically in hepatocytes, and most of the liver injury associated...
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