- Surrogate Endpoints in Second-Line Trials of Targeted Agents in Metastatic Colorectal Cancer: A Literature-Based Systematic Review and Meta-Analysis
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Cremolini , Antoniotti C, Pietrantonio F, Berenato R, Tampellini M, Baratelli , Salvatore , Marmorino , Borelli B, Nichetti F, Bironzo P, Sonetto C, Di Bartolomeo M, de Braud F, Loupakis F, Falcone A, Di Maio M
- KMID: 2388329
- Cancer Res Treat.
- 2017 Jul;49(3):834-845.
- doi: 10.4143/crt.2016.249
PURPOSE: The purpose of this study was to evaluate progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints of overall survival (OS) in modern clinical trials investigating the... -
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